Pawan Kumar obtained his M.S. and Ph.D. degrees from the prestigious All India Institute of Medical Sciences (AIIMS), New Delhi, India. After completing his Ph.D. degree, Kumar went to the United States in 1997 and completed four years of postdoctoral training at the University of Illinois and Northwestern University, Chicago, IL, USA. Kumar works as an Assistant Professor at the Department of Otolaryngology–Head and Neck Surgery, Ohio State University, Columbus, OH, USA. He came to the Ohio State University Medical Center after working for 5 years at the University of Michigan, Ann Arbor, MI, USA. The focus of his laboratory has been to elucidate the molecular determinants of aggressive and metastatic head and neck cancer. His lab has recently shown that an inflammatory chemokine, IL-6, plays an important role in cancer metastasis by inducing epithelial mesenchymal transition (EMT). In another study, his lab demonstrated that survivin is one of the key molecules that modulate chemoresistance in head and neck cancer patients and that treatment with a novel survivin inhibitor YM155 could enhance the effectiveness of chemotherapy in these patients. Kumar’s laboratory has a number of exciting projects currently going on and they are designed to examine the role of tumor microenvironment in mediating tumor metastasis, investigate the mechanisms that contribute to chemoresistance/radioresistance in tumor cells and tumor associated endothelial cells, and examine the role of microRNAs in head and neck cancer. Kumar has been rewarded for his outstanding work with a number of awards including the NII Young Scientist Award, the Burroughs Wellcome Fellowship, and the Gramm Travel Fellowship. He has published more than 40 articles in scientific journals, conference proceedings, and book chapters.
Biography Updated on 21 December 2013