Sven Horke was born in 1971. He studied biology at the University of Hamburg, Germany. At that time, his focus was on biochemistry and he performed his Diploma thesis at the University Medical Center Hamburg-Eppendorf, dealing with RNA-protein interaction in a neurobiological setting. For his Ph.D. starting in 2000 and a one-year postdoc time afterwards, he joined a lab in the Department of General Virology at the Heinrich-Pette-Institute for Experimental Virology and Immunology, Hamburg, Germany. Again he worked on RNA-protein interactions, this time with a Hepatitis B virus background. Afterwards, in 2004 he moved to the University Medical Center of the Johannes Gutenberg University Mainz, Germany and started a new research group dealing with cell and redox signalling pathways with a special focus on human paraoxonase enzymes. Given the relevance of these enzymes in various biological processes, his research now covers aspects of redox signalling, cell death pathways, inflammatory responses, atherosclerosis, and host defence. For his success, he received the research awards of the Robert-Müller Foundation in 2008 and that of the Boehringer-Ingelheim Foundation in 2011. Furthermore, he served among the scientific board of the 4th International Conference on Paraoxonases and published several papers on paraoxonase enzymes and cellular stress pathways.
Biography Updated on 12 July 2011