Nils Cordes is currently the Head of Radiobiology and Leader of the Molecular and Cellular Radiobiology research group at the National Center for Radiation Research in Oncology-OncoRay at the Dresden University of Technology, Dresden, Germany. Cordes graduated from the University of Erlangen-N ürnberg, Germany, in 1998, and was trained in radiation oncology and radiobiology at the Universities of Erlangen-Nürnberg, Tübingen, and Munich. In 1998, he has obtained his M.D. degree. From 2000 to 2005, Cordes was a Scientist at the Bundeswehr Institute of Radiobiology, Munich, Germany. He was appointed as a Group Leader for Biological and Molecular Targeting at the OncoRay before he became a Professor of Molecular and Cellular Radiobiology at the Dresden University of Technology in 2010. Cordes has published extensively in the area of radiobiology and the impact of cell-matrix and cell-cell interactions for radio- and chemo-resistance of tumors. His main research interests are integrins and how these receptors confer therapy resistance in human cancers, especially head and neck, lung, brain, and pancreas. The work of Cordes pinpointed (i) the importance of cell-matrix interactions for tumor cell survival, (ii) the need for more complex in vitro methodology mimicking physiological growth conditions, and (iii) the mechanistic connection between chromatin organization, integrin-regulated cell morphology, and radiogenic double-strand break induction/repair and cell survival.
Biography Updated on 16 August 2012