Todd E. Gillis
Todd E. Gillis received his B.S. and M.S. degrees from the University of Guelph and his Ph.D. degree from Simon Fraser University. He then worked at the Department of Bioengineering in the School of Medicine at the University of Washington as an NSERC Postdoctoral Fellow. He joined the Department of Integrative Biology at the University of Guelph in 2005. The work in the Gillis laboratory is focused on the vertebrate heart and the mechanisms that regulate its function. The underlying theme of this work is the evolution of protein structure and function and the role this plays in determining the physiological scope of organisms. This work integrates the use of (i) quantitative PCR and proteomic approaches (2D DIGE) to study how gene and protein expression change in the heart in response to environmental stressors, (ii) recombinant protein studies to characterize how changes in sequence of the cardiac regulatory proteins influence their function, and (iii) muscle mechanic studies to determine how changes in protein function alter muscle activation.
Biography Updated on 6 February 2012