Peter Little

Articles in Scholarly Journals [Incomplete List]

  1. Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents
    Journal of Diabetes and its Complications, vol. 21, no. 2, pp. 108–117, 2007
  2. Hierarchical Bayes variable selection and microarray experiments
    Journal of Multivariate Analysis, vol. 98, no. 4, pp. 852–872, 2007
  3. Genetic dissection of gene regulation in multiple mouse tissues
    Mammalian Genome, vol. 17, no. 6, pp. 490–495, 2006
  4. Normalization procedures and detection of linkage signal in genetical-genomics experiments
    Nature Genetics, vol. 38, no. 8, Article ID ng0806-855, 1 pages, 2006
  5. Genomic anatomy of the Tyrp1 (brown) deletion complex
    Proceedings of the National Academy of Sciences, vol. 103, no. 10, pp. 3704–3709, 2006
  6. Insulin Resistance and Atherosclerosis
    Endocrine Reviews, vol. 27, no. 3, pp. 242–259, 2006
  7. Clinical Thiazolidinediones as PPARγ Ligands with the Potential for the Prevention of Cardiovascular Disease in Diabetes
    Current Diabetes Reviews, vol. 2, no. 2, pp. 227–239, 2006
  8. Androgens Stimulate Human Vascular Smooth Muscle Cell Proteoglycan Biosynthesis and Increase Lipoprotein Binding
    Endocrinology, vol. 146, no. 4, pp. 2085–2090, 2005
  9. Structure and function of the human genome
    Genome Research, vol. 15, no. 12, pp. 1759–1766, 2005
  10. Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells
    Kidney International, vol. 68, no. 6, pp. 2756–2765, 2005
  11. Diabetes induces Na/H exchange activity and hypertrophy of rat mesenteric but not basilar arteries
    Diabetes Research and Clinical Practice, vol. 70, no. 3, pp. 201–208, 2005
  12. Regulation of glycosaminoglycan structure and atherogenesis
    Cellular and Molecular Life Sciences (CMLS), vol. 61, no. 11, pp. 1296–1306, 2004
  13. Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans
    Diabetologia, vol. 47, no. 5, pp. 837–843, 2004
  14. Fenofibrate modifies human vascular smooth muscle proteoglycans and reduces lipoprotein binding
    Diabetologia, vol. 47, no. 12, pp. 2105–2113, 2004
  15. High glucose potentiates mitogenic responses of cultured ovine coronary smooth muscle cells to platelet derived growth factor and transforming growth factor-ß1
    Diabetes Research and Clinical Practice, vol. 59, no. 2, pp. 93–101, 2003
  16. GANESH: Software for Customized Annotation of Genome Regions
    Genome Research, vol. 13, no. 9, pp. 2195–2202, 2003
  17. Nature, nurture and human disease
    Nature, vol. 421, no. 6921, Article ID nature01401, 2 pages, 2003
  18. Impact of Sleep Apnea on Sympathetic Nervous System Activity in Heart Failure
    Chest, vol. 123, no. 4, pp. 1119–1126, 2003
  19. Troglitazone Stimulates Repair of the Endothelium and Inhibits Neointimal Formation in Denuded Rat Aorta
    Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 23, no. 5, pp. 762–768, 2003
  20. Inhibitory Activity of Clinical Thiazolidinedione Peroxisome Proliferator Activating Receptor-gamma Ligands Toward Internal Mammary Artery, Radial Artery, and Saphenous Vein Smooth Muscle Cell Proliferation
    Circulation, vol. 107, no. 20, pp. 2548–2550, 2003
  21. Proteoglycans Synthesized by Arterial Smooth Muscle Cells in the Presence of Transforming Growth Factor-beta1 Exhibit Increased Binding to LDLs
    Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 22, no. 1, pp. 55–60, 2002
  22. Differential effects of gemfibrozil on migration, proliferation and proteoglycan production in human vascular smooth muscle cells
    Atherosclerosis, vol. 162, no. 1, pp. 119–129, 2002
  23. Mechanical strain stimulates a mitogenic response in coronary vascular smooth muscle cells via release of basic fibroblast growth factor
    American Journal of Hypertension, vol. 14, no. 11, pp. 1128–1134, 2001
  24. The flamingo-related mouse Celsr family (Celsr1?3) genes exhibit distinct patterns of expression during embryonic development
    Mechanisms of Development, vol. 109, no. 1, pp. 91–94, 2001
  25. Troglitazone, but not rosiglitazone, inhibits Na/H exchange activity and proliferation of macrovascular endothelial cells
    Journal of Diabetes and its Complications, vol. 15, no. 3, pp. 120–127, 2001
  26. Nature Genetics, vol. 27, no. 3, pp. 229–230, 2001
  27. Disruption of a Novel Imprinted Zinc-Finger Gene, [ITAL]ZNF215,[/ITAL] in Beckwith-Wiedemann Syndrome
    The American Journal of Human Genetics, vol. 66, no. 5, pp. 1473–1484, 2000
  28. Effect of moderate alcohol upon obstructive sleep apnoea
    European Respiratory Journal, vol. 16, no. 5, pp. 909–913, 2000
  29. Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on Chromosome 9
    Mammalian Genome, vol. 11, no. 5, pp. 392–394, 2000
  30. A 500-kb Sequence-Ready Cosmid Contig and Transcript Map of theMEN1Region on 11q13
    Genomics, vol. 55, no. 1, pp. 49–56, 1999
  31. Nature, vol. 402, no. 6761, pp. 467–468, 1999
  32. A 7.5 Mb Sequence-Ready PAC Contig and Gene Expression Map of Human Chromosome 11p13-p14.1
    Genome Research, vol. 9, no. 11, pp. 1074–1086, 1999
  33. A human p57(KIP2) transgene is not activated by passage through the maternal mouse germline
    Human Molecular Genetics, vol. 8, no. 12, pp. 2211–2219, 1999
  34. Journal of Hypertension, vol. 17, no. 3, pp. 373–379, 1999
  35. Report of the Sixth International Workshop on Human Chromosome 11 Mapping 1998
    Cytogenetic and Genome Research, vol. 86, no. 3-4, pp. 168–186, 1999
  36. Mechanisms regulating the vascular smooth muscle Na/H exchanger (NHE-1) in diabetes
    Biochemistry and Cell Biology, vol. 76, no. 5, pp. 751–759, 1998
  37. Journal of Cardiovascular Pharmacology, vol. 32, no. 4, pp. 621–628, 1998
  38. Nature Genetics, vol. 19, no. 3, pp. 222–222, 1998
  39. A Sequence-Ready 3-Mb PAC Contig Covering 16 Breakpoints of the Wilms Tumor/Anirida Region of Human Chromosome 11p13
    Genomics, vol. 53, no. 2, pp. 155–163, 1998
  40. Nature, vol. 395, no. 6705, pp. 842–843, 1998
  41. MCelsr1 is an evolutionarily conserved seven-pass transmembrane receptor and is expressed during mouse embryonic development
    Mechanisms of Development, vol. 78, no. 1-2, pp. 91–95, 1998
  42. Urokinase plasminogen activator induces smooth muscle cell migration: key role of growth factor-like domain
    FEBS Letters, vol. 414, no. 2, pp. 471–474, 1997
  43. Genomic Organization and Chromosomal Localization of a Member of the MAP Kinase Phosphatase Gene Family to Human Chromosome 11p15.5 and a Pseudogene to 10q11.2
    Genomics, vol. 42, no. 2, pp. 284–294, 1997
  44. Celsr1, a Neural-Specific Gene Encoding an Unusual Seven-Pass Transmembrane Receptor, Maps to Mouse Chromosome 15 and Human Chromosome 22qter
    Genomics, vol. 45, no. 1, pp. 97–104, 1997
  45. Characterization of a KRAB Family Zinc Finger Gene,ZNF195,Mapping to Chromosome Band 11p15.5
    Genomics, vol. 45, no. 2, pp. 451–455, 1997
  46. The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts
    Human Molecular Genetics, vol. 6, no. 6, pp. 859–867, 1997
  47. Genome analysis
    Nature, vol. 382, no. 6590, Article ID 382408a0, 1 pages, 1996
  48. Woman's meat, a man's poison
    Nature, vol. 382, no. 6591, Article ID 382494a0, 1 pages, 1996
  49. Mapping the human Y chromosome by fingerprinting cosmid clones.
    Genome Research, vol. 6, no. 4, pp. 235–248, 1996
  50. VASCULAR LOCALIZATION OF THE 11?-HYDROXYSTEROID DEHYDROGENASE TYPE II ENZYME
    Clinical and Experimental Pharmacology and Physiology, vol. 23, no. 6-7, pp. 549–551, 1996
  51. Physical Analysis of the Region Deleted in thetw18Allele of the Mousetcl-4Complementation Group
    Genomics, vol. 36, no. 1, pp. 39–46, 1996
  52. Positional cloning of genes involved in the Beckwith-Wiedemann syndrome, hemihypertrophy, and associated childhood tumors
    Medical and Pediatric Oncology, vol. 27, no. 5, pp. 490–494, 1996
  53. Cloning of candidate genes involved in the Beckwith-Wiedemann syndrome and childhood tumors
    Medical and Pediatric Oncology, vol. 27, no. 5, pp. 495–497, 1996
  54. Human NicotinamideN-Methyltransferase Gene: Molecular Cloning, Structural Characterization and Chromosomal Localization
    Genomics, vol. 29, no. 3, pp. 555–561, 1995
  55. Intracellular pH in vascular smooth muscle: regulation by sodium-hydrogen exchange and multiple sodium dependent HCO3- mechanisms
    Cardiovascular Research, vol. 29, no. 2, pp. 239–246, 1995
  56. Navigational progress
    Nature, vol. 377, no. 6547, Article ID 377286a0, 1 pages, 1995
  57. A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11: distal p13 to proximal p15.1
    Genomics, vol. 25, no. 2, pp. 447–461, 1995
  58. Multiple Genetic Loci within 11p15 Defined by Beckwith-Wiedemann Syndrome Rearrangement Breakpoints and Subchromosomal Transferable Fragments
    Proceedings of the National Academy of Sciences, vol. 92, no. 26, pp. 12456–12460, 1995
  59. Genetic and Physiological Association of Diabetes Susceptibility with Raised Na+/H+ Exchange Activity
    Proceedings of the National Academy of Sciences, vol. 91, no. 13, pp. 5898–5902, 1994
  60. Transforming Growth Factor-ß1 Regulates the Expression of Ryanodine-Sensitive Ca2+ Oscillations in Cardiac Myocytes
    Biochemical and Biophysical Research Communications, vol. 204, no. 2, pp. 678–684, 1994
  61. An Integrated Physical Map of 210 Markers Assigned to the Short Arm of Human Chromosome 11
    Genomics, vol. 21, no. 3, pp. 538–550, 1994
  62. Leu143 in the Putative Fourth Membrane Spanning Domain Is Critical for Amiloride Inhibition of an Epithelial Na+/H+ Exchanger Isoform (NHE-2)
    Biochemical and Biophysical Research Communications, vol. 193, no. 2, pp. 532–539, 1993
  63. Dihydropyridine Ca2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells
    European Journal of Pharmacology: Molecular Pharmacology, vol. 244, no. 3, pp. 269–275, 1993
  64. The end of the beginning
    Nature, vol. 362, no. 6419, Article ID 362408a0, 1 pages, 1993
  65. Small and perfectly formed
    Nature, vol. 366, no. 6452, Article ID 366204a0, 1 pages, 1993
  66. The worm turns and delivers
    Nature, vol. 356, no. 6364, Article ID 356014a0, 1 pages, 1992
  67. Mapping the way ahead
    Nature, vol. 359, no. 6394, Article ID 359367a0, 1 pages, 1992
  68. High-resolution localization of 69 potential human zinc finger protein genes: A number are clustered
    Genomics, vol. 12, no. 2, pp. 254–263, 1992
  69. Report of the Second Chromosome 11 Workshop
    Genomics, vol. 12, no. 3, pp. 620–625, 1992
  70. Endothelin-1 and endothelin-3 stimulate calcium mobilization by different mechanisms in vascular smooth muscle
    Biochemical and Biophysical Research Communications, vol. 183, no. 2, pp. 694–700, 1992
  71. Generating 'cloned DNA maps'
    Trends in Biotechnology, vol. 10, pp. 33–35, 1992
  72. Complementary questions
    Nature, vol. 352, no. 6330, Article ID 352020a0, 1 pages, 1991
  73. IONIC MECHANISMS REGULATING SODIUM ENTRY INTO VASCULAR SMOOTH MUSCLE
    Clinical and Experimental Pharmacology and Physiology, vol. 18, no. 2, pp. 117–120, 1991
  74. MULTIPLE GROWTH ABNORMALITIES IN VASCULAR SMOOTH MUSCLE FROM SPONTANEOUSLY HYPERTENSIVE RATS
    Clinical and Experimental Pharmacology and Physiology, vol. 18, no. 5, pp. 319–322, 1991
  75. MECHANISMS INVOLVED IN THE STIMULATION OF ALDOSTERONE PRODUCTION BY ANGIOTENSIN II, VASOPRESSIN AND ENDOTHELIN
    Clinical and Experimental Pharmacology and Physiology, vol. 17, no. 4, pp. 263–267, 1990
  76. SODIUM-DEPENDENT, ETHYLISOPROPYLAMILORIDE-SENSITIVE MECHANISMS REGULATE INTRACELLULAR pH IN HUMAN VASCULAR SMOOTH MUSCLE
    Clinical and Experimental Pharmacology and Physiology, vol. 17, no. 4, pp. 297–301, 1990
  77. Clone maps made simple
    Nature, vol. 346, no. 6285, Article ID 346611b0, 1 pages, 1990
  78. Gene mapping and the human genome mapping project
    Current Opinion in Cell Biology, vol. 2, no. 3, pp. 478–484, 1990
  79. Drug treatment in hypertension ? metabolic side effects of drugs
    European Journal of Clinical Pharmacology, vol. 38, no. 4, pp. 407–408, 1990
  80. Synthèse et évaluation pharmacologique d'analogues mercapto et thioacétylés des cannabidiol et ?8-tetrahydrocannabinol
    European Journal of Medicinal Chemistry, vol. 24, no. 3, pp. 293–297, 1989
  81. Stereochemical effects of 11-OH-?8-THC-dimethylheptyl in mice and dogs
    Pharmacology Biochemistry and Behavior, vol. 32, no. 3, pp. 661–666, 1989
  82. Smart 2, a cosmid vector with a phage lambda origin for both systematic chromosome walking and P-element-mediated gene transfer in Drosophila
    Gene, vol. 64, no. 1, pp. 173–177, 1988
  83. Two homologous oncogenes, HST1 and INT2, are closely located in human genome
    Biochemical and Biophysical Research Communications, vol. 157, no. 2, pp. 828–835, 1988
  84. SPONTANEOUS OSCILLATIONS IN CYTOPLASMIC FREE CALCIUM CONCENTRATION IN VASCULAR SMOOTH MUSCLE: A POTENTIAL MECHANISM ASSOCIATED WITH MYOGENIC TONE
    Clinical and Experimental Pharmacology and Physiology, vol. 15, no. 4, pp. 281–284, 1988
  85. Absence of Methylation of a CpG-Rich Region at the 5' End of the MIC2 Gene on the Active X, the Inactive X, and the Y Chromosome
    Proceedings of the National Academy of Sciences, vol. 85, no. 15, pp. 5605–5609, 1988
  86. Correction: Genomic Sequence of hst, a Transforming Gene Encoding a Protein Homologous to Fibroblast Growth Factors and he int-s-encoded Protein
    Proceedings of the National Academy of Sciences, vol. 85, no. 6, pp. 1967–1967, 1988
  87. Genomic Sequence of hst, a Transforming Gene Encoding a Protein Homologous to Fibroblast Growth Factors and the int-2-Encoded Protein
    Proceedings of the National Academy of Sciences, vol. 84, no. 20, pp. 7305–7309, 1987
  88. REGULATION OF SODIUM INFLUX AND SODIUM, POTASSIUM PUMP ACTIVITY BY A SODIUM-HYDROGEN ANTIPORT IN RAT VASCULAR SMOOTH MUSCLE
    Clinical and Experimental Pharmacology and Physiology, vol. 14, no. 3, pp. 191–195, 1987
  89. Lorist2, a cosmid with transcriptional terminators insulating vector genes from interference by promoters within the insert: effect on DNA yield and cloned insert frequency
    Gene, vol. 53, no. 2-3, pp. 275–281, 1987
  90. The effect of MDMA (“Ecstasy”) and its optical isomers on schedule-controlled responding in mice
    Pharmacology Biochemistry and Behavior, vol. 26, no. 2, pp. 425–426, 1987
  91. Tissue disposition of 63H9sarin and its metabolites in mice
    Toxicology and Applied Pharmacology, vol. 83, no. 3, pp. 412–419, 1986
  92. A cosmid vector for systematic chromosome walking
    Gene, vol. 49, no. 1, pp. 9–22, 1986
  93. Relationship between the pharmacological effects and the biodisposition of 63H9diisopropylfluorophosphate in mice after inhalation
    Toxicology and Applied Pharmacology, vol. 79, no. 3, pp. 502–510, 1985
  94. Temperature-dependent disposition of 614C9benzo(a)pyrene in the spiny lobster, Panulirus argus
    Toxicology and Applied Pharmacology, vol. 77, no. 2, pp. 325–333, 1985
  95. Relationship between the biodisposition of 63H9soman and its pharmacological effects in mice
    Toxicology and Applied Pharmacology, vol. 80, no. 3, pp. 409–420, 1985
  96. KIDNEY BROKERAGE
    The Lancet, vol. 325, no. 8419, p. 53, 1985
  97. A Cosmid Vector That Facilitates Restriction Enzyme Mapping
    Proceedings of the National Academy of Sciences, vol. 82, no. 10, pp. 3159–3163, 1985
  98. Sequencing techniques: A close look at the genome
    Nature, vol. 310, no. 5976, Article ID 310369a0, 1 pages, 1984
  99. Desensitization of the alpha1 adrenoceptor system in vascular smooth muscle
    Biochemical Pharmacology, vol. 33, no. 7, pp. 1143–1145, 1984
  100. 3-Methylcholanthrene does not induce in vitro xenobiotic metabolism in spiny lobster hepatopancreas, or affect in vivo disposition of benzo6a9pyrene
    Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol. 78, no. 1, pp. 241–245, 1984
  101. The effects of endogenous phospholipase A2 activation on beta adrenoceptor function in cardiac cells
    Journal of Molecular and Cellular Cardiology, vol. 15, no. 11, pp. 759–767, 1983
  102. Some observations and implications of hepatitis B markers in Saudi Arabia
    Journal of Infection, vol. 7, pp. 79–79, 1983
  103. Journal of Medicinal Chemistry, vol. 25, no. 6, pp. 622–626, 1982
  104. Journal of Medicinal Chemistry, vol. 25, no. 8, pp. 887–892, 1982
  105. Inhibitors of hepatic mixed function oxidases—V. Inhibition of aminopyrine N-demethylation and enhancement of aniline hydroxylation by benzoxazole derivatives
    Biochemical Pharmacology, vol. 31, no. 9, pp. 1795–1798, 1982
  106. Globin pseudogenes
    Cell, vol. 28, no. 4, pp. 683–684, 1982
  107. Polyhalogenated biphenyls and phenobarbital: Evaluation as inducers of drug metabolizing enzymes in the sheepshead, Archosargus probatocephalus
    Chemico-Biological Interactions, vol. 36, no. 2, pp. 229–248, 1981
  108. Model for antenatal diagnosis of ß-thalassaemia and other monogenic disorders by molecular analysis of linked DNA polymorphisms
    Nature, vol. 285, no. 5761, Article ID 285144a0, 3 pages, 1980
  109. THE STRUCTURE OF THE HUMAN ?-GLOBIN GENE LOCUS AND ITS RELATION TO THE ?/?-GLOBIN GENE LOCUS
    Annals of the New York Academy of Sciences, vol. 344, no. 1 Fourth Cooley, pp. 73–75, 1980
  110. Significance of bacterial and white cell counts in midstream urines.
    Journal of Clinical Pathology, vol. 33, no. 1, pp. 58–60, 1980
  111. Structure of the Human Ggamma -Agamma -delta -  -Globin Gene Locus
    Proceedings of the National Academy of Sciences, vol. 76, no. 10, pp. 4827–4831, 1979
  112. Structure of the human fetal globin gene locus
    Nature, vol. 278, no. 5701, Article ID 278227a0, 4 pages, 1979
  113. Polymorphisms of human ?-globin genes in Mediterranean populations
    Nature, vol. 282, no. 5736, Article ID 282316a0, 2 pages, 1979
  114. Restriction enzyme analysis of the ?-globin gene in DNA from ?U-thalassaemic subjects from Ferrara
    Biochemical and Biophysical Research Communications, vol. 91, no. 2, pp. 548–553, 1979
  115. Isolation and partial sequence of recombinant plasmids containing human a-, ß- and ?-globin cDNA fragments
    Nature, vol. 273, no. 5664, Article ID 273640a0, 3 pages, 1978
  116. Inhibitors of hepatic mixed function oxidases—II Some benzimidazole, benzoxazole and benzothiazole derivatives
    Biochemical Pharmacology, vol. 25, no. 24, pp. 2747–2750, 1976
  117. ACUTE PYELONEPHRITIS INCIDENCE OF REINFECTION IN 100 PATIENTS
    The Lancet, vol. 288, no. 7476, pp. 1277–1278, 1966