Gary S. Shaw

Gary S. Shaw received his B.S. degree with honor in biochemistry and chemistry from McMaster University in Hamilton, Ontario, Canada. He completed his Ph.D. degree in physical organic chemistry at McMaster in 1988 under the direction of Dr. R. F. Childs. Following this, Dr. Shaw was an Alberta Heritage Foundation for Medical Research Postdoctoral Fellow with Dr. B. D. Sykes in the Department of Biochemistry at the University of Alberta. Dr. Shaw joined the faculty at the University of Western Ontario in London, Ontario, Canada, in 1992. He is currently a Professor of biochemistry and Canada Research Chair in structural neurobiology. His research interests include the structure and function of calcium-binding proteins and the mechanisms of ubiquitylation.

Biography Updated on 31 January 2008

Personal Home Page

http://www.biochem.uwo.ca/fac/shaw/

Articles in Scholarly Journals [Incomplete List]

  1. Amide Exchange Shows Calcium-Induced Conformational Changes Are Transmitted to the Dimer Interface of S100B
    Biochemistry, vol. 46, no. 25, pp. 7478–7487, 2007
  2. From the Cover: Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease
    Proceedings of the National Academy of Sciences, vol. 104, no. 9, pp. 3095–3100, 2007
  3. The solution structure of the protein ydhA from Escherichia coli
    Journal of Biomolecular NMR, vol. 35, no. 4, pp. 295–300, 2006
  4. Calcium-dependent and -independent interactions of the S100 protein family
    Biochemical Journal, vol. 396, no. 2, p. 201, 2006
  5. Biochemistry, vol. 45, no. 49, pp. 14695–14705, 2006
  6. Biochemistry, vol. 45, no. 9, pp. 3005–3013, 2006
  7. Solution structure of the Escherichia coli protein ydhR: A putative mono-oxygenase
    Protein Science, vol. 14, no. 12, pp. 3115–3120, 2005
  8. Ubiquitin Manipulation by an E2 Conjugating Enzyme Using a Novel Covalent Intermediate
    Journal of Biological Chemistry, vol. 280, no. 36, pp. 31732–31738, 2005
  9. Solution Structure of the Flexible Class II Ubiquitin-conjugating Enzyme Ubc1 Provides Insights for Polyubiquitin Chain Assembly
    Journal of Biological Chemistry, vol. 279, no. 45, pp. 47139–47147, 2004
  10. Human S100B Protein Interacts with the Escherichia coli Division Protein FtsZ in a Calcium-sensitive Manner
    Journal of Biological Chemistry, vol. 279, no. 18, pp. 18806–18813, 2004
  11. Biochemistry, vol. 43, no. 29, pp. 9361–9371, 2004
  12. A Novel S100 Target Conformation Is Revealed by the Solution Structure of the Ca2+-S100B-TRTK-12 Complex
    Journal of Biological Chemistry, vol. 278, no. 8, pp. 6251–6257, 2003
  13. Unmasking the Annexin I Interaction from the Structure of Apo-S100A11
    Structure, vol. 11, no. 7, pp. 887–897, 2003
  14. Journal of Biomolecular NMR, vol. 26, no. 2, pp. 147–155, 2003
  15. Journal of Biomolecular NMR, vol. 23, no. 3, pp. 255–256, 2002
  16. Biochemistry, vol. 41, no. 17, pp. 5421–5428, 2002
  17. Journal of Biomolecular NMR, vol. 22, no. 2, pp. 191–192, 2002
  18. Folding and stability of the b subunit of the F1F0 ATP synthase
    Protein Science, vol. 11, no. 5, pp. 1227–1238, 2002
  19. Biochemistry, vol. 41, no. 11, pp. 3637–3646, 2002
  20. Structure of a Conjugating Enzyme-Ubiquitin Thiolester Intermediate Reveals a Novel Role for the Ubiquitin Tail
    Structure, vol. 9, no. 10, pp. 897–904, 2001
  21. Sequence specific analysis of the heterogeneous glycan chain from peanut peroxidase by 1H-NMR spectroscopy
    Phytochemistry, vol. 53, no. 1, pp. 135–144, 2000
  22. Journal of Biomolecular NMR, vol. 16, no. 4, pp. 351–352, 2000
  23. Journal of Biomolecular NMR, vol. 18, no. 4, pp. 319–327, 2000
  24. The solution structure of the C-terminal domain of the Mu B transposition protein
    The EMBO Journal, vol. 19, no. 21, pp. 5625–5634, 2000
  25. Specificity and Zn2+ Enhancement of the S100B Binding Epitope TRTK-12
    Journal of Biological Chemistry, vol. 274, no. 3, pp. 1502–1508, 1999
  26. The Dimerization Domain of the b Subunit of the Escherichia coli F1F0-ATPase
    Journal of Biological Chemistry, vol. 274, no. 43, pp. 31094–31101, 1999
  27. A change-in-hand mechanism for S100 signalling
    Biochemistry and Cell Biology, vol. 76, no. 2-3, pp. 324–333, 1998
  28. A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form
    Structure, vol. 6, no. 2, pp. 211–222, 1998
  29. Solution and solid state conformation of the human EGF receptor transmembrane region
    Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1371, no. 2, pp. 241–253, 1998
  30. Journal of Biomolecular NMR, vol. 10, no. 1, pp. 77–88, 1997
  31. Biochemistry, vol. 35, no. 23, pp. 7429–7438, 1996
  32. Biochemistry, vol. 35, no. 27, pp. 8805–8814, 1996
  33. Anatomy of a Flexer?DNA Complex inside a Higher-Order Transposition Intermediate
    Cell, vol. 85, no. 5, pp. 761–771, 1996
  34. Biochemistry, vol. 35, no. 38, pp. 12591–12601, 1996
  35. Metal ion binding by proteins Current Opinion in Structural Biology 1992, 2:57…-60
    Current Opinion in Structural Biology, vol. 2, no. 1, pp. 57–60, 1992
  36. Biochemistry, vol. 31, no. 40, pp. 9572–9580, 1992
  37. Biochemistry, vol. 30, no. 34, pp. 8339–8347, 1991
  38. Journal of the American Chemical Society, vol. 113, no. 15, pp. 5557–5563, 1991
  39. Journal of the American Chemical Society, vol. 111, no. 14, pp. 5424–5429, 1989
  40. Journal of the American Chemical Society, vol. 110, no. 10, pp. 3013–3017, 1988
  41. Journal of the American Chemical Society, vol. 109, no. 18, pp. 5362–5366, 1987
  42. Structure, energetics and homoaromaticity
    Pure and Applied Chemistry, vol. 58, no. 1, pp. 111–128, 1986