Debashis Ghosh

Articles in Scholarly Journals [Incomplete List]

  1. Empirical Bayes Identication of Tumor Progression Genes from Microarray Data
    Biometrical Journal, vol. 49, no. 1, pp. 68–77, 2007
  2. Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer
    Modern Pathology, vol. 20, no. 5, Article ID 3800769, 6 pages, 2007
  3. Associations of BMI, TV-Watching Time, and Physical Activity on Respiratory Symptoms and Asthma in 5th Grade Schoolchildren in Taipei, Taiwan
    Journal of Asthma, vol. 44, no. 5, pp. 397–401, 2007
  4. Toenails as a Biomarker of Inorganic Arsenic Intake From Drinking Water and Foods
    Journal of Toxicology and Environmental Health, Part A, vol. 70, no. 2, pp. 148–158, 2007
  5. A Functional Genetic Polymorphism on Human Carbonyl Reductase 1 (CBR1 V88I) Impacts on Catalytic Activity and NADPH Binding Affinity
    Drug Metabolism and Disposition, vol. 35, no. 6, pp. 973–980, 2007
  6. Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma
    Cancer Research, vol. 67, no. 7, pp. 3461–3467, 2007
  7. Feature Selection and Molecular Classification of Cancer Using Genetic Programming
    Neoplasia, vol. 9, no. 4, pp. 292–303, 2007
  8. Molecular Concepts Analysis Links Tumors, Pathways, Mechanisms, and Drugs
    Neoplasia, vol. 9, no. 5, pp. 443–454, 2007
  9. Risk Factors for Mortality Among Patients With Diabetes: The Translating Research Into Action for Diabetes (TRIAD) Study
    Diabetes Care, vol. 30, no. 7, pp. 1736–1741, 2007
  10. Identification of New Genetic Regions More Prevalent in Nontypeable Haemophilus influenzae Otitis Media Strains than in Throat Strains
    Journal of Clinical Microbiology, vol. 44, no. 12, pp. 4316–4325, 2006
  11. A Semiparametric Binary Regression Model Involving Monotonicity Constraints
    Scandinavian Journal of Statistics, vol. 33, no. 4, pp. 673–697, 2006
  12. Semiparametric Global Cross-ratio Models for Bivariate Censored Data
    Scandinavian Journal of Statistics, vol. 33, no. 4, pp. 609–619, 2006
  13. Shrunken p-Values for Assessing Differential Expression with Applications to Genomic Data Analysis
    Biometrics, vol. 62, no. 4, pp. 1099–1106, 2006
  14. COPA--cancer outlier profile analysis
    Bioinformatics, vol. 22, no. 23, pp. 2950–2951, 2006
  15. Eigengene-based linear discriminant model for tumor classification using gene expression microarray data
    Bioinformatics, vol. 22, no. 21, pp. 2635–2642, 2006
  16. Peptide length-based prediction of peptide-MHC class II binding
    Bioinformatics, vol. 22, no. 22, pp. 2761–2767, 2006
  17. Incorporating monotonicity into the evaluation of a biomarker
    Biostatistics, vol. 8, no. 2, pp. 402–413, 2006
  18. Risk Factors for Respiratory Symptoms and Asthma in the Residential Environment of 5th Grade Schoolchildren in Taipei, Taiwan
    Journal of Asthma, vol. 43, no. 5, pp. 355–361, 2006
  19. Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: Correlation with androgen independence
    The Prostate, vol. 66, no. 13, pp. 1437–1444, 2006
  20. Semiparametric inferences for association with semi-competing risks data
    Statistics in Medicine, vol. 25, no. 12, pp. 2059–2070, 2006
  21. Modelling tumour biology–progression relationships in screening trials
    Statistics in Medicine, vol. 25, no. 11, pp. 1872–1884, 2006
  22. The false discovery rate: a variable selection perspective
    Journal of Statistical Planning and Inference, vol. 136, no. 8, pp. 2668–2684, 2006
  23. Finding cancer subtypes in microarray data using random projections
    Neurocomputing, vol. 69, no. 16-18, pp. 2258–2267, 2006
  24. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
    Cancer Cell, vol. 8, no. 5, pp. 393–406, 2005
  25. Structural Basis of Antigen Mimicry in a Clinically Relevant Melanoma Antigen System
    Journal of Biological Chemistry, vol. 280, no. 50, pp. 41546–41552, 2005
  26. Autoantibody Signatures in Prostate Cancer
    New England Journal of Medicine, vol. 353, no. 12, pp. 1224–1235, 2005
  27. Probabilistic model of the human protein-protein interaction network
    Nature Biotechnology, vol. 23, no. 8, Article ID nbt1103, 8 pages, 2005
  28. Mining for regulatory programs in the cancer transcriptome
    Nature Genetics, vol. 37, no. 6, Article ID ng1578, 4 pages, 2005
  29. Measurement scale does moderate the association between the serotonin transporter gene and trait anxiety: comments on Munafo et al
    Molecular Psychiatry, vol. 10, no. 10, Article ID 4001708, 1 pages, 2005
  30. Biochemistry, vol. 44, no. 19, pp. 7095–7106, 2005
  31. Bayesian classification of tumours by using gene expression data
    Journal of the Royal Statistical Society: Series B (Statistical Methodology), vol. 67, no. 2, pp. 219–234, 2005
  32. Classification and Selection of Biomarkers in Genomic Data Using LASSO
    Journal of Biomedicine and Biotechnology, vol. 2005, no. 2, pp. 147–154, 2005
  33. A model-based scan statistic for identifying extreme chromosomal regions of gene expression in human tumors
    Bioinformatics, vol. 21, no. 12, pp. 2867–2874, 2005
  34. Identification of GATA3 as a Breast Cancer Prognostic Marker by Global Gene Expression Meta-analysis
    Cancer Research, vol. 65, no. 24, pp. 11259–11264, 2005
  35.  -Methylacyl-CoA Racemase Protein Expression Is Associated with the Degree of Differentiation in Breast Cancer Using Quantitative Image Analysis
    Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 6, pp. 1418–1423, 2005
  36. Decreased  -Methylacyl CoA Racemase Expression in Localized Prostate Cancer is Associated with an Increased Rate of Biochemical Recurrence and Cancer-Specific Death
    Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 6, pp. 1424–1432, 2005
  37. Linkage Disequilibrium: Ancient History Drives the New Genetics
    Human Heredity, vol. 59, no. 2, pp. 118–124, 2005
  38. BMC Bioinformatics, vol. 6, no. 1, p. 26, 2005
  39. BMC Genomics, vol. 5, no. 1, p. 94, 2004
  40. BMC Microbiology, vol. 4, no. 1, p. 1, 2004
  41. Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases: Lessons from a Rapid Autopsy Program
    Cancer Research, vol. 64, no. 24, pp. 9209–9216, 2004
  42. FUNCTIONAL SIGNIFICANCE OF A NATURAL ALLELIC VARIANT OF HUMAN CARBONYL REDUCTASE 3 (CBR3)
    Drug Metabolism and Disposition, vol. 33, no. 2, pp. 254–257, 2004
  43. Humoral Immune Response to  -Methylacyl-CoA Racemase and Prostate Cancer
    CancerSpectrum Knowledge Environment, vol. 96, no. 11, pp. 834–843, 2004
  44. Mutations in X-linked ichthyosis disrupt the active site structure of estrone/DHEA sulfatase
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol. 1739, no. 1, pp. 1–4, 2004
  45. Accelerated Rates Regression Models for Recurrent Failure Time Data
    Lifetime Data Analysis, vol. 10, no. 3, pp. 247–261, 2004
  46. Identification of Shared Components and Sparse Networks in Gene Expression Time-Course Data
    The Journal of VLSI Signal Processing-Systems for Signal, Image, and Video Technology, vol. 38, no. 3, pp. 277–286, 2004
  47. Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
    Proceedings of the National Academy of Sciences, vol. 101, no. 25, pp. 9309–9314, 2004
  48. Altered Expression of Genes of the Bmp/Smad and Wnt/Calcium Signaling Pathways in the Cone-only Nrl-/- Mouse Retina, Revealed by Gene Profiling Using Custom cDNA Microarrays
    Journal of Biological Chemistry, vol. 279, no. 40, pp. 42211–42220, 2004
  49. Mixture models for assessing differential expression in complex tissues using microarray data
    Bioinformatics, vol. 20, no. 11, pp. 1663–1669, 2004
  50. Suppression of human cytochrome P450 aromatase activity by monoclonal and recombinant antibody fragments and identification of a stable antigenic complex
    The Journal of Steroid Biochemistry and Molecular Biology, vol. 88, no. 3, pp. 235–245, 2004
  51. 3a/ß,20ß-Hydroxysteroid dehydrogenase (porcine testicular carbonyl reductase) also has a cysteine residue that is involved in binding of cofactor NADPH
    The Journal of Steroid Biochemistry and Molecular Biology, vol. 88, no. 4-5, pp. 393–398, 2004
  52. Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits
    American Journal of Medical Genetics, vol. 127B, no. 1, pp. 85–89, 2004
  53. Covariate adjustment in the analysis of microarray data from clinical studies
    Functional & Integrative Genomics, vol. 5, no. 1, pp. 18–27, 2004
  54. Nonparametric methods for analyzing replication origins in genomewide data
    Functional & Integrative Genomics, vol. 5, no. 1, pp. 28–31, 2004
  55. Statistical issues and methods for meta-analysis of microarray data: a case study in prostate cancer
    Functional & Integrative Genomics, vol. 3, no. 4, pp. 180–188, 2003
  56. Impact of diabetes on cognitive function among older Latinos A population-based cohort study
    Journal of Clinical Epidemiology, vol. 56, no. 7, pp. 686–693, 2003
  57. Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association
    Journal of Biological Chemistry, vol. 278, no. 25, pp. 22989–22997, 2003
  58. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    Proceedings of the National Academy of Sciences, vol. 100, no. 20, pp. 11606–11611, 2003
  59. Impact of Antidiabetic Medications on Physical and Cognitive Functioning of Older Mexican Americans with Diabetes Mellitus A Population-based Cohort Study
    Annals of Epidemiology, vol. 13, no. 5, pp. 369–376, 2003
  60. Goodness-of-Fit Methods for Additive-Risk Models in Tumorigenicity Experiments
    Biometrics, vol. 59, no. 3, pp. 721–726, 2003
  61. Semiparametric Analysis of Recurrent Events Data in the Presence of Dependent Censoring
    Biometrics, vol. 59, no. 4, pp. 877–885, 2003
  62. Penalized Discriminant Methods for the Classification of Tumors from Gene Expression Data
    Biometrics, vol. 59, no. 4, pp. 992–1000, 2003
  63. BMC Bioinformatics, vol. 4, no. 1, p. 36, 2003
  64. Diabetes as a Predictor of Change in Functional Status Among Older Mexican Americans: A population-based cohort study
    Diabetes Care, vol. 26, no. 2, pp. 314–319, 2003
  65. The polycomb group protein EZH2 is involved in progression of prostate cancer
    Nature, vol. 419, no. 6907, Article ID nature01075, 5 pages, 2002
  66. Mixture modelling of gene expression data from microarray experiments
    Bioinformatics, vol. 18, no. 2, pp. 275–286, 2002
  67. Resampling methods for variance estimation of singular value decomposition analyses from microarray experiments
    Functional & Integrative Genomics, vol. 2, no. 3, pp. 92–97, 2002
  68. alpha-Methylacyl Coenzyme A Racemase as a Tissue Biomarker for Prostate Cancer
    JAMA: The Journal of the American Medical Association, vol. 287, no. 13, pp. 1662–1670, 2002
  69. Purification, characterization and crystallization of human placental estrone/dehydroepiandrosterone sulfatase, a membrane-bound enzyme of the endoplasmic reticulum
    The Journal of Steroid Biochemistry and Molecular Biology, vol. 78, no. 5, pp. 441–450, 2001
  70. Molecular mechanisms of estrogen recognition and 17-keto reduction by human 17ß-hydroxysteroid dehydrogenase 1
    Chemico-Biological Interactions, vol. 130-132, no. 1-3, pp. 637–650, 2001
  71. Multiple Conformations of Catalytic Serine and Histidine in Acetylxylan Esterase at 0.90 A
    Journal of Biological Chemistry, vol. 276, no. 14, pp. 11159–11166, 2001
  72. Porcine Carbonyl Reductase. STRUCTURAL BASIS FOR A FUNCTIONAL MONOMER IN SHORT CHAIN DEHYDROGENASES/REDUCTASES
    Journal of Biological Chemistry, vol. 276, no. 21, pp. 18457–18463, 2001
  73. Nature, vol. 412, no. 6849, pp. 822–826, 2001
  74. Structure of the insecticidal bacterial d-endotoxin Cry3Bb1 of Bacillus thuringiensis
    Acta Crystallographica Section D Biological Crystallography, vol. 57, no. 8, pp. 1101–1109, 2001
  75. Journal of Mammary Gland Biology and Neoplasia, vol. 5, no. 3, pp. 259–270, 2000
  76. Structure of an activity suppressing Fab fragment to cytochrome P450 aromatase: insights into the antibody–antigen interactions
    Molecular Immunology, vol. 36, no. 7, pp. 423–432, 1999
  77. cis- and trans-2,3,3a,4,5,9b-Hexahydro-1H-benz[e]indoles: synthesis and evaluation of dopamine D2 and D3 receptor binding affinity
    European Journal of Medicinal Chemistry, vol. 34, no. 6, pp. 487–503, 1999
  78. Structure of the ternary complex of human 17beta -hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+
    Proceedings of the National Academy of Sciences, vol. 96, no. 3, pp. 840–845, 1999
  79. Structure of Ustilago maydis Killer Toxin KP6 alpha -Subunit. A MULTIMERIC ASSEMBLY WITH A CENTRAL PORE
    Journal of Biological Chemistry, vol. 274, no. 29, pp. 20425–20431, 1999
  80. Statistical methods for analyzing repeated measures
    Journal of Pharmacological and Toxicological Methods, vol. 42, no. 3, pp. 157–162, 1999
  81. Journal of Organic Chemistry, vol. 64, no. 4, pp. 1407–1409, 1999
  82. Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 Å resolution
    Acta Crystallographica Section D Biological Crystallography, vol. 55, no. 1, pp. 93–102, 1999
  83. Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase
    Acta Crystallographica Section D Biological Crystallography, vol. 55, no. 4, pp. 779–784, 1999
  84. Equilin
    Acta Crystallographica Section C Crystal Structure Communications, vol. 55, no. 3, pp. 425–427, 1999
  85. Characterization of Molecular and Catalytic Properties of Intact and Truncated Human 17 -Hydroxysteroid Dehydrogenase Type 2 Enzymes: Intracellular Localization of the Wild-Type Enzyme in the Endoplasmic Reticulum
    Endocrinology, vol. 140, no. 7, pp. 3334–3341, 1999
  86. Acetyl xylan esterase II from Penicillium purpurogenum is similar to an esterase from Trichoderma reesei but lacks a cellulose binding domain
    FEBS Letters, vol. 423, no. 1, pp. 35–38, 1998
  87. Structure and function of steroid dehydrogenases involved in hypertension, fertility, and cancer
    Steroids, vol. 62, no. 1, pp. 95–100, 1997
  88. The preferential dopamine D3 receptor agonist cis-8-OH-PBZI induces limbic Fos expression in rat brain
    European Journal of Pharmacology, vol. 339, no. 2-3, pp. 261–270, 1997
  89. Characterization of Structural and Functional Properties of Human 17 -Hydroxysteroid Dehydrogenase Type 1 Using Recombinant Enzymes and Site-Directed Mutagenesis
    Molecular Endocrinology, vol. 11, no. 1, pp. 77–86, 1997
  90. Origin of Substrate Specificity of Human and Rat 17 -Hydroxysteroid Dehydrogenase Type 1, Using Chimeric Enzymes and Site-Directed Substitutions
    Endocrinology, vol. 138, no. 8, pp. 3532–3539, 1997
  91. The fascinating complexities of steroid-binding enzymes
    Current Opinion in Structural Biology, vol. 6, no. 6, pp. 813–823, 1996
  92. Characterization of crystals ofPenicillium purpurogenum acetyl xylan esterase from high-resolution X-ray diffraction
    Proteins: Structure, Function, and Genetics, vol. 24, no. 4, pp. 523–524, 1996
  93. Fructose-1,6-bisphosphatase. Primary structure of the rabbit liver enzyme. 'Intermediate' variability of an oligomeric protein
    FEBS Letters, vol. 389, no. 3, pp. 249–252, 1996
  94. 8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: A Potent Full Dopamine D1 Agonist Containing a Rigid β-Phenyldopamine Pharmacophore
    Journal of Medicinal Chemistry, vol. 39, no. 2, pp. 549–555, 1996
  95. An Improved Method for the Preparation of Cyclic Conjugated Nitroolefins
    Synthesis, vol. 1996, no. 02, pp. 195–197, 1996
  96. Structure of uncomplexed and linoleate-bound Candida cylindracea cholesterol esterase
    Structure, vol. 3, no. 3, pp. 279–288, 1995
  97. Structure of human estrogenic 17?-hydroxysteroid dehydrogenase at 2.20 ? resolution
    Structure, vol. 3, no. 5, pp. 503–513, 1995
  98. Synthesis and evaluation of -1-methyl-3--propyl-2,3,3a,4,5,9b-hexahydro-1-benz[]indoles for dopamine D and D receptor binding affinity
    European Journal of Medicinal Chemistry, vol. 30, no. 12, pp. 943–948, 1995
  99. Monomeric and dimeric forms of cholesterol esterase from Candida cylindracea Primary structure, identity in peptide patterns, and additional microheterogeneity
    FEBS Letters, vol. 337, no. 2, pp. 123–127, 1994
  100. The refined three-dimensional structure of 3?,20?-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
    Structure, vol. 2, no. 7, pp. 629–640, 1994
  101. Mechanism of inhibition of 3?,20?-hydroxysteroid dehydrogenaseby a licorice-derived steroidal inhibitor
    Structure, vol. 2, no. 10, pp. 973–980, 1994
  102. Three-dimensional model of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase and relationships to the NADP+-dependent enzyme (carbonyl reductase)
    FEBS Letters, vol. 322, no. 2, pp. 139–142, 1993
  103. Crystallization and preliminary x-ray diffraction studies of a mammalian steroid dehydrogenase
    The Journal of Steroid Biochemistry and Molecular Biology, vol. 46, no. 1, pp. 103–104, 1993
  104. Crystallization and Preliminary X-ray Diffraction Analysis of the Complex of Human Placental 17ß-Hydroxysteroid Dehydrogenase with NADP+
    Journal of Molecular Biology, vol. 234, no. 1, pp. 242–244, 1993
  105. Three-Dimensional Structur of Holo 3 , 20 -Hydroxysteroid Dehydrogenase: A Member of a Short-Chain Dehydrogenase Family
    Proceedings of the National Academy of Sciences, vol. 88, no. 22, pp. 10064–10068, 1991
  106. Crystallization of prostatic binding protein
    Journal of Steroid Biochemistry, vol. 31, no. 4, pp. 365–370, 1988