Arifa S. Khan
Arifa S. Khan is a Senior Investigator and Chief of Molecular Retrovirology Unit, Center for Biologics Evaluation and Research (CBER). He received his Ph.D. degree in microbiology from The George Washington University, Washington DC, USA, in 1979 on research mentored by Dr. John Stephenson, NCI, related to identification of feline leukemia/sarcoma retrovirus gag-polyproteins and their role in tumorigenesis. He joined the CBER in 1991, where he has established a research program that continues to address emerging public health issues related to retrovirus safety in biological products. His laboratory’s research efforts are directed toward developing novel assays for detection of endogenous retroviruses and latent DNA viruses in vaccine cell substrates and evaluating the risk of retrovirus infections using the rhesus macaque model. His extensive experience and expertise in endogenous murine leukemia retroviruses has facilitated developing an algorithm for chemical induction and detection of latent viruses and to address public health concerns related to XMRV and other retrovirus transmissions and infections in humans. His regulatory responsibilities in CBER include review of investigational new drugs and biological license applications for a variety of candidate vaccines and contributing to development of FDA, ICH, PHS, and WHO guidance documents related to cell substrates, vaccines, therapeutics, and xenotransplantation.
Biography Updated on 2 December 2010