Viktor Brabec

Articles in Scholarly Journals [Incomplete List]

  1. Recognition of DNA Three-Way Junctions by Metallosupramolecular Cylinders: Gel Electrophoresis Studies
    Chemistry - A European Journal, vol. 13, no. 14, pp. 3871–3877, 2007
  2. NMR analysis of duplex d(CGCGATCGCG)2 modified by Î?- and Î?-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study
    JBIC Journal of Biological Inorganic Chemistry, vol. 12, no. 3, pp. 293–293, 2007
  3. 1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin
    Archives of Biochemistry and Biophysics, vol. 459, no. 2, pp. 264–272, 2007
  4. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)]
    Biochemical Pharmacology, vol. 73, no. 12, pp. 1887–1900, 2007
  5. Raman spectroscopy of DNA modified by intrastrand cross-links of antitumor cisplatin
    Journal of Structural Biology, vol. 159, no. 1, pp. 1–8, 2007
  6. Dual Triggering of DNA Binding and Fluorescence via Photoactivation of a Dinuclear Ruthenium(II) Arene Complex
    Inorganic Chemistry, vol. 46, no. 12, pp. 5059–5068, 2007
  7. Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin
    Nucleic Acids Research, vol. 35, no. 6, pp. 1812–1821, 2007
  8. High-Throughput Screening Identifies Novel Agents Eliciting Hypersensitivity in Fanconi Pathway-Deficient Cancer Cells
    Cancer Research, vol. 67, no. 5, pp. 2169–2177, 2007
  9. Recognition of DNA modified by trans-[PtCl2NH3(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex
    FEBS Journal, vol. 273, no. 2, pp. 301–314, 2006
  10. Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes
    FEBS Journal, vol. 273, no. 15, pp. 3467–3478, 2006
  11. Molecular Aspects of Antitumor Effects of a New Platinum(IV) Drug
    Molecular Pharmacology, vol. 70, no. 5, pp. 1708–1719, 2006
  12. Journal of Medicinal Chemistry, vol. 49, no. 15, pp. 4665–4673, 2006
  13. Journal of Medicinal Chemistry, vol. 49, no. 15, pp. 4674–4683, 2006
  14. Journal of Medicinal Chemistry, vol. 49, no. 8, pp. 2640–2651, 2006
  15. Journal of Medicinal Chemistry, vol. 49, no. 26, pp. 7792–7798, 2006
  16. Thermodynamic properties of damaged DNA and its recognition by xeroderma pigmentosum group A protein and replication protein A
    Archives of Biochemistry and Biophysics, vol. 446, no. 1, pp. 1–10, 2006
  17. Tröger's base scaffold in racemic and chiral fashion as a spacer for bisdistamycin formation. Synthesis and DNA binding study
    Tetrahedron, vol. 62, no. 36, pp. 8591–8600, 2006
  18. DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity
    Drug Resistance Updates, vol. 9, no. 3, pp. 111–122, 2006
  19. Recognition of cisplatin-damaged DNA by p53 protein: Critical role of the p53 C-terminal domain
    Biochemical and Biophysical Research Communications, vol. 339, no. 2, pp. 477–484, 2006
  20. NMR analysis of duplex d(CGCGATCGCG)2 modified by Î?- and Î?-[Ru(bpy)2(m-GHK)]Cl2 and DNA photocleavage study
    JBIC Journal of Biological Inorganic Chemistry, vol. 12, no. 3, pp. 279–292, 2006
  21. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand
    JBIC Journal of Biological Inorganic Chemistry, vol. 10, no. 7, pp. 722–731, 2005
  22. Structure and Unique Interactions with DNA of a CationicTrans-Platinum Complex with the Nonplanar Bicyclic Piperidinopiperidine Ligand
    Angewandte Chemie International Edition, vol. 44, no. 19, pp. 2885–2887, 2005
  23. Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked bytrans-diamminedichloroplatinum(II)
    Biopolymers, vol. 77, no. 4, pp. 222–229, 2005
  24. DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins
    Biochemical and Biophysical Research Communications, vol. 332, no. 4, pp. 1034–1041, 2005
  25. Conformation of DNA Modified by Monofunctional Ru(II) Arene Complexes: Recognition by DNA Binding Proteins and Repair. Relationship to Cytotoxicity
    Chemistry & Biology, vol. 12, no. 1, pp. 121–129, 2005
  26. Modifications of DNA by platinum complexesRelation to resistance of tumors to platinum antitumor drugs
    Drug Resistance Updates, vol. 8, no. 3, pp. 131–146, 2005
  27. Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of Antitumor trans-[PtCl2(NH3)(thiazole)]
    Nucleic Acids Research, vol. 33, no. 18, pp. 5819–5828, 2005
  28. Chiral Differentiation of DNA Adducts Formed by Enantiomeric Analogues of Antitumor Cisplatin Is Sequence-Dependent
    Biophysical Journal, vol. 88, no. 6, pp. 4159–4169, 2005
  29. Effects of Monofunctional Adducts of Platinum(II) Complexes on Thermodynamic Stability and Energetics of DNA Duplexes
    Biophysical Journal, vol. 88, no. 2, pp. 1207–1214, 2004
  30. Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin
    Nucleic Acids Research, vol. 32, no. 18, pp. 5546–5552, 2004
  31. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand
    Biochemical Pharmacology, vol. 67, no. 6, pp. 1097–1109, 2004
  32. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding
    Journal of Inorganic Biochemistry, vol. 98, no. 10, pp. 1560–1569, 2004
  33. Biochemistry, vol. 43, no. 24, pp. 7776–7786, 2004
  34. Biochemistry, vol. 42, no. 13, pp. 3996–3996, 2003
  35. Biochemistry, vol. 42, no. 20, pp. 6321–6332, 2003
  36. Biochemistry, vol. 42, no. 39, pp. 11544–11554, 2003
  37. DNA Binding by Antitumor trans-[PtCl2(NH3)(thiazole)]. Protein Recognition and Nucleotide Excision Repair of Monofunctional Adducts
    Biochemistry, vol. 42, no. 3, pp. 792–800, 2003
  38. Biochemistry, vol. 42, no. 5, pp. 1234–1244, 2003
  39. Chemical Research in Toxicology, vol. 16, no. 11, pp. 1424–1432, 2003
  40. Recognition of DNA modified by antitumor cisplatin by “latent” and “active” protein p53
    Biochemical Pharmacology, vol. 65, no. 8, pp. 1305–1316, 2003
  41. Formation of platinated GG cross-links on DNA by photoactivation of a platinum(IV) azide complex
    Journal of Biological Inorganic Chemistry, vol. 8, no. 7, pp. 741–745, 2003
  42. DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes
    Nucleic Acids Research, vol. 31, no. 22, pp. 6450–6460, 2003
  43. Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers
    Proceedings of the National Academy of Sciences, vol. 100, no. 25, pp. 14623–14628, 2003
  44. Activation of Trans Geometry in Bifunctional Mononuclear Platinum Complexes by a Piperidine Ligand: MECHANISTIC STUDIES ON ANTITUMOR ACTION
    Journal of Biological Chemistry, vol. 278, no. 48, pp. 47516–47525, 2003
  45. DNA Interstrand Cross-links of the Novel Antitumor Trinuclear Platinum Complex BBR3464. CONFORMATION, RECOGNITION BY HIGH MOBILITY GROUP DOMAIN PROTEINS, AND NUCLEOTIDE EXCISION REPAIR
    Journal of Biological Chemistry, vol. 277, no. 50, pp. 48076–48086, 2002
  46. DNA bending and unwinding due to the major 1,2-GG intrastrand cross-link formed by antitumor cis-diamminedichloroplatinum(II) are flanking-base independent
    Nucleic Acids Research, vol. 30, no. 13, pp. 2894–2898, 2002
  47. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
    Journal of Biological Inorganic Chemistry, vol. 7, no. 4-5, pp. 397–404, 2002
  48. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium
    Journal of Biological Inorganic Chemistry, vol. 7, no. 7-8, pp. 725–734, 2002
  49. Differential genotoxic effects of antitumor trans-6PtCl2(E-iminoether)29 and cisplatin in Escherichia coli
    Journal of Inorganic Biochemistry, vol. 90, no. 3-4, pp. 155–158, 2002
  50. Recognition of Major DNA Adducts of Enantiomeric Cisplatin Analogs by HMG Box Proteins and Nucleotide Excision Repair of These Adducts
    Chemistry & Biology, vol. 9, no. 5, pp. 629–638, 2002
  51. Molecular aspects of resistance to antitumor platinum drugs
    Drug Resistance Updates, vol. 5, no. 3-4, pp. 147–161, 2002
  52. Biochemistry, vol. 41, no. 36, pp. 10994–10999, 2002
  53. Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(III) in cell-free media
    Journal of Biological Inorganic Chemistry, vol. 6, no. 4, pp. 435–445, 2001
  54. Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex
    Nucleic Acids Research, vol. 29, no. 10, pp. 2034–2040, 2001
  55. Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair
    The EMBO Journal, vol. 20, no. 13, pp. 3554–3564, 2001
  56. Thermal and Thermodynamic Properties of Duplex DNA Containing Site-specific Interstrand Cross-link of Antitumor Cisplatin or Its Clinically Ineffective Trans Isomer
    Journal of Biological Chemistry, vol. 276, no. 13, pp. 9655–9661, 2001
  57. Different Recognition of DNA Modified by Antitumor Cisplatin and Its Clinically Ineffective trans Isomer by Tumor Suppressor Protein p53
    Journal of Biological Chemistry, vol. 276, no. 19, pp. 16064–16069, 2001
  58. Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464
    Journal of Biological Chemistry, vol. 276, no. 25, pp. 22191–22199, 2001
  59. Sequence Specificity, Conformation, and Recognition by HMG1 Protein of Major DNA Interstrand Cross-links of Antitumor Dinuclear Platinum Complexes
    Journal of Biological Chemistry, vol. 275, no. 21, pp. 15789–15798, 2000
  60. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups
    Journal of Biological Inorganic Chemistry, vol. 5, no. 3, pp. 364–368, 2000
  61. Biochemistry, vol. 39, no. 41, pp. 12639–12649, 2000
  62. DNA sensor for the determination of antitumor platinum compounds
    Electrochimica Acta, vol. 45, no. 18, pp. 2929–2932, 2000
  63. Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl2(Me2SO4)4Ru] in cell-free media
    Biochemical Pharmacology, vol. 60, no. 12, pp. 1761–1771, 2000
  64. Sequence-dependent conformational changes in DNA induced by polynuclear platinum complexes
    Journal of Inorganic Biochemistry, vol. 77, no. 1-2, pp. 43–46, 1999
  65. DNA interactions of cisplatin tethered to the DNA minor groove binder distamycin
    European Journal of Biochemistry, vol. 266, no. 2, pp. 392–402, 1999
  66. Biochemistry, vol. 38, no. 21, pp. 6781–6790, 1999
  67. Biochemistry, vol. 38, no. 34, pp. 10997–11005, 1999
  68. DNA interactions of antitumor trans-[PtCl2(NH3)(quinoline)]
    European Journal of Biochemistry, vol. 254, no. 3, pp. 547–557, 1998
  69. Biochemistry, vol. 35, no. 51, pp. 16705–16713, 1996
  70. The effect of ionic strength on melting of DNA modified by platinum(II) complexes
    Biophysical Chemistry, vol. 60, no. 3, pp. 135–142, 1996
  71. DNA adducts of antitumor trans-[PtCl2 (E-imino ether)2]
    Nucleic Acids Research, vol. 24, no. 2, pp. 336–341, 1996
  72. Superhelical torsion controls DNA interstrand cross-linking by antitumor cis- diamminedichloroplatinum(II)
    Nucleic Acids Research, vol. 24, no. 20, pp. 3918–3925, 1996
  73. Biochemistry, vol. 34, no. 38, pp. 12379–12387, 1995
  74. Biochemistry, vol. 33, no. 6, pp. 1316–1322, 1994
  75. Restriction-enzyme cleavage of DNA modified by platinum(II) complexes
    European Journal of Biochemistry, vol. 216, no. 1, pp. 183–187, 1993
  76. DNA Interstrand Cross-Links of Trans-Diamminedichloroplatinum(II) are Preferentially Formed Between Guanine and Complementary Cytosine Residues
    Proceedings of the National Academy of Sciences, vol. 90, no. 11, pp. 5345–5349, 1993
  77. Biochemistry, vol. 31, no. 49, pp. 12397–12402, 1992
  78. Reinterpretation of fluorescence of terbium ion-DNA complexes
    Biophysical Chemistry, vol. 33, no. 1, pp. 55–61, 1989
  79. Electrochemical analysis of antitumour platinum drugs and their complexes with DNA
    Bioelectrochemistry and Bioenergetics, vol. 19, no. 1, pp. 145–160, 1988
  80. The effect of platinum derivatives on interfacial properties of DNA
    Biophysical Chemistry, vol. 28, no. 3, pp. 191–197, 1987
  81. DNA modified by platinum derivatives cannot adopt the A-form
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 867, no. 1-2, pp. 31–35, 1986
  82. The Effect of Combined Treatment with Platinum Complexes and Ionizing Radiation on DNA in Vitro
    International Journal of Radiation Biology, vol. 50, no. 6, pp. 995–1007, 1986
  83. Raman scattering from nucleic acids adsorbed at a silver electrode
    Biophysical Chemistry, vol. 23, no. 1-2, pp. 63–70, 1985
  84. Platinum determination in -dichlorodiammineplatinum(II)-DNA complexes by differential pulse polarography
    Analytical Biochemistry, vol. 142, no. 1, pp. 16–23, 1984
  85. Polarographic activity of the antitumor drug cis-dichlorodiammineplatinum (II). The effect of hydrolysis and trans-isomerization of the drug
    Experientia, vol. 40, no. 5, pp. 446–451, 1984
  86. Conformational changes in DNA induced by its adsorption at negatively charged surfaces The effects of base composition in DNA and the chemical nature of the adsorbent
    Bioelectrochemistry and Bioenergetics, vol. 11, no. 2-3, pp. 245–255, 1983
  87. 433 — Nucleic acid analysis by voltammetry at carbon electrodes1
    Bioelectrochemistry and Bioenergetics, vol. 8, no. 4, pp. 437–449, 1981
  88. Interaction of nucleic acids with electrically charged surfaces VII. The effect of ionic strength of neutral medium on the conformation of dna adsorbed on the mercury electrode
    Biophysical Chemistry, vol. 11, no. 1, pp. 1–7, 1980
  89. An electrochemical analysis of changes in properties of DNA caused by ionizing and ultraviolet radiations
    Radiation and Environmental Biophysics, vol. 17, no. 2, pp. 129–141, 1980
  90. Study of thermal and acid denaturation of DNA by means of voltammetry at graphite electrodes
    Biopolymers, vol. 18, no. 10, pp. 2397–2404, 1979
  91. Temperature dependence of the interfacial behavior of uracil derivatives
    Biophysical Chemistry, vol. 8, no. 2, pp. 151–162, 1978
  92. Potential and structure controlled interfacial behavior of uracil derivatives
    Biophysical Chemistry, vol. 7, no. 4, pp. 253–268, 1978
  93. 231 - Adsorption of Mixtures of Complementary and Non-Complementary Nucleic Acid Bases at the Mercury-Solution Interface
    Bioelectrochemistry and Bioenergetics, vol. 5, no. 4, pp. 635–649, 1978
  94. Interaction of nucleic acids with electrically charged surfaces II. Conformational changes in double-helical polynucleotides
    Biophysical Chemistry, vol. 4, no. 1, pp. 79–92, 1976
  95. Interaction of nucleic acids with electrically charged surfaces VI. A comparative study on the electrochemical behaviour of native and denatured dnas at graphite electrodes
    Biophysical Chemistry, vol. 9, no. 4, pp. 289–297, 1975
  96. Adsorption of single-stranded and double-helical polynucleotides on the mercury electrode
    Biopolymers, vol. 11, no. 12, pp. 2577–2589, 1972
  97. The relation between the polarographic behaviour of DNA and its conformation in solution
    Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, vol. 262, no. 2, pp. 125–134, 1972