Alessandro Paiardini serves as an Assistant Professor of biochemistry and bioinformatics at University of Rome, Sapienza. He received the Ph.D. degree in biochemical sciences from the Department of Biochemical Sciences, University of Rome, in 2005. He is Member of the Italian Society of Biochemistry (SIB), and serves as reviewer of several journals in the biochemistry field. His research activity is mainly concerned with the development and application of computational tools, including homology modeling, molecular dynamics, docking and evolutionary analysis, aimed at understanding at a molecular level the structure and function relationship, ligand binding, catalytic mechanism, evolution, and folding of a series of PLP-dependent enzymes, which are targets for the development of therapeutic agents, including: SHMT (tumors and malaria), threonine aldolase, and alanine racemase (antimicrobial and antifungal targets).
Biography Updated on 24 October 2012