Jean-Claude Lavoie has received a Ph.D. degree in 1998 from the University of Montreal, Canada. He acts as an Associate Professor at the Department of Pediatrics with an affiliation with the Department of Nutrition of the same university. His laboratory is located in the Research Centre of the Sainte-Justine Hospital in Montreal. Lavoie is particularly interested in the presence of oxidative stress in newborn infants, especially in premature newborns who have immature antioxidant defenses. These infants receive an important oxidant load by the oxygen supplement and by their parenteral nutrition. This mode of nutrition, which is essential for growth, is contaminated by several oxidant molecules such as peroxides and aldehydes. These molecules are implied in several pathological complications associated with prematurity such as Broncho pulmonary dysplasia and hepatic cholestasis. Lavoie is committed in the understanding of the links between this oxidant load, the neonatal antioxidant defense, and these pathologies as well as in the long-term impact of neonatal exposure to oxidant molecules on lipid and glucose metabolism in adulthood. His areas of expertise include neonatal oxidative stress, parenteral nutrition, prematurity, newborn, type-2 diabetes, metabolic syndrome, pulmonary diseases, generation and action of reactive species, glutathione and thiol redox biology, oxidation of macromolecules and biomarkers, nutrition, and health and nutraceuticals.
Biography Updated on 29 August 2012