Jack A. Taylor

Jack A. Taylor received a B.A. degree from Carleton College, an M.D. degree from the University of Wisconsin, and a Ph.D. degree in epidemiology from the School of Public Health at the University of North Carolina at Chapel Hill. Professor Taylor is licensed in North Carolina, and holds board certifications in public health and general preventive medicine. He holds Adjunct Professorships from the Department of Epidemiology, Department of Medicine, and the Lineberger Comprehensive Cancer Center, the University of North Carolina at Chapel Hill, as well as from the Department of Medicine at Duke University. He serves as a Senior Researcher in the U.S. Public Health Service at the National Institute of Environmental Health Sciences (NIEHS), and holds a joint appointment at the Laboratory of Molecular Carcinogenesis at NIEHS.

Biography Updated on 3 September 2008

Personal Home Page

http://www.niehs.nih.gov/research/atniehs/labs/lmc/molecular/index.cfm

Articles in Scholarly Journals [Incomplete List]

  1. Folate and one-carbon metabolism gene polymorphisms and their associations with oral facial clefts
    American Journal of Medical Genetics Part A, vol. 146A, no. 4, pp. 440–449, 2008
  2. XRCC1 and DNA polymerase ß in cellular protection against cytotoxic DNA single-strand breaks
    Cell Research, vol. 18, no. 1, Article ID cr20087, 15 pages, 2008
  3. Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data
    European Journal of Human Genetics, vol. 15, no. 10, Article ID 5201875, 7 pages, 2007
  4. Detection of Pre-Invasive Lung Cancer: Technical Aspects of the LIFE Project
    Toxicologic Pathology, vol. 35, no. 1, pp. 65–74, 2007
  5. TAGster: efficient selection of LD tag SNPs in single or multiple populations
    Bioinformatics, vol. 23, no. 23, pp. 3254–3255, 2007
  6. Assessing human germ-cell mutagenesis in the Postgenome Era: A celebration of the legacy of William Lawson (Bill) Russell
    Environmental and Molecular Mutagenesis, vol. 48, no. 2, pp. 71–95, 2007
  7. Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells
    Cancer Letters, vol. 246, no. 1-2, pp. 24–33, 2007
  8. Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 616, no. 1-2, pp. 60–69, 2007
  9. Folic acid supplements and risk of facial clefts: national population based case-control study
    BMJ, vol. 334, no. 7591, pp. 464–464, 2007
  10. Val153Met Polymorphism of Catechol-O-Methyltransferase and Prevalence of Uterine Leiomyomata
    Reproductive Sciences, vol. 14, no. 2, pp. 117–120, 2007
  11. Lycopene Intake and Prostate Cancer Risk: Effect Modification by Plasma Antioxidants and the XRCC1 Genotype
    Nutrition and Cancer, vol. 55, no. 1, pp. 13–20, 2006
  12. How Well Do HapMap Haplotypes Identify Common Haplotypes of Genes? A Comparison with Haplotypes of 334 Genes Resequenced in the Environmental Genome Project
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 1, pp. 133–137, 2006
  13. DNA repair gene polymorphisms and probability of p53 mutation in bladder cancer
    Molecular Carcinogenesis, vol. 45, no. 9, pp. 715–719, 2006
  14. APE1 genotype and risk of bladder cancer: Evidence for effect modification by smoking
    International Journal of Cancer, vol. 118, no. 12, pp. 3170–3173, 2006
  15. Approximate Bayesian inference for quantiles
    Journal of Nonparametric Statistics, vol. 17, no. 3, pp. 385–400, 2005
  16. Chromosomal abnormalities in bronchial epithelium from smokers, nonsmokers, and lung cancer patients
    Cancer Genetics and Cytogenetics, vol. 159, no. 2, pp. 137–142, 2005
  17. Lead Exposure as a Risk Factor for Amyotrophic Lateral Sclerosis
    Neurodegenerative Diseases, vol. 2, no. 3-4, pp. 195–201, 2005
  18. No Association Between SOD2 or NQO1 Genotypes and Risk of Bladder Cancer
    Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 3, pp. 753–754, 2005
  19. Application of the GA/KNN method to SELDI proteomics data
    Bioinformatics, vol. 20, no. 10, pp. 1638–1640, 2004
  20. VEGF Promoter Haplotype and Amyotrophic Lateral Sclerosis (ALS)
    Journal of Neurogenetics, vol. 18, no. 2, pp. 429–434, 2004
  21. Analytical and statistical methods to evaluate microsatellite allelic imbalance in small amounts of DNA
    Laboratory Investigation, vol. 84, no. 5, Article ID 3700076, 8 pages, 2004
  22. Mini-and microsatellite mutations in children from Chernobyl accident cleanup workers
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 559, no. 1-2, pp. 143–151, 2004
  23. Variants of developmental genes (TGFA, TGFB3, andMSX1) and their associations with orofacial clefts: A case-parent triad analysis
    Genetic Epidemiology, vol. 24, no. 3, pp. 230–239, 2003
  24. Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: Assessing gene-environment interactions in case-parent triads
    Genetic Epidemiology, vol. 25, no. 4, pp. 367–374, 2003
  25. Cadmium is a mutagen that acts by inhibiting mismatch repair
    Nature Genetics, vol. 34, no. 3, Article ID ng1172, 3 pages, 2003
  26. Exploring the Effects of Methylenetetrahydrofolate Reductase Gene Variants C677T and A1298C on the Risk of Orofacial Clefts in 261 Norwegian Case-Parent Triads
    American Journal of Epidemiology, vol. 157, no. 12, pp. 1083–1091, 2003
  27. Bayesian Latent Variable Models for Median Regression on Multiple Outcomes
    Biometrics, vol. 59, no. 2, pp. 296–304, 2003
  28. Pooled Analysis and Meta-analysis of Glutathione S-Transferase M1 and Bladder Cancer: A HuGE Review
    American Journal of Epidemiology, vol. 156, no. 2, pp. 95–109, 2002
  29. Potential for Selection Bias with Tumor Tissue Retrieval in Molecular Epidemiology Studies
    Annals of Epidemiology, vol. 12, no. 1, pp. 1–6, 2002
  30. Mucin phenotype and microsatellite instability in early multiple gastric cancers
    International Journal of Cancer, vol. 100, no. 4, pp. 419–424, 2002
  31. A Novel Host Cell Reactivation Assay to Assess Homologous Recombination Capacity in Human Cancer Cell Lines
    Biochemical and Biophysical Research Communications, vol. 281, no. 1, pp. 212–219, 2001
  32. Role of matrix metalloproteinase-9 in progression of mouse skin carcinogenesis
    Molecular Carcinogenesis, vol. 31, no. 2, pp. 74–82, 2001
  33. Vitamin D receptor polymorphisms and prostate cancer
    Molecular Carcinogenesis, vol. 27, no. 1, pp. 18–23, 2000
  34. Nature Genetics, vol. 21, no. 4, pp. 362–362, 1999
  35. Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2)
    Carcinogenesis, vol. 20, no. 9, pp. 1727–1731, 1999
  36. Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease [published erratum appears in Toxicol Sci 1999 Oct;51(2):317]
    Toxicological Sciences, vol. 47, no. 2, pp. 135–143, 1999
  37. Avoided and avoidable risks of cancer
    Carcinogenesis, vol. 18, no. 1, pp. 97–105, 1997
  38. Genetic Analysis of Complex Diseases
    Science, vol. 275, no. 5304, pp. 1327–1330, 1997
  39. Molecular Mechanisms of Lung Cancer: Interaction of Environmental and Genetic Factors
    Chest, vol. 109, no. 3 Supplement, pp. 14S–19S, 1996
  40. Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect
    The Lancet, vol. 347, no. 8997, pp. 295–297, 1996
  41. Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer
    Molecular Carcinogenesis, vol. 17, no. 3, pp. 160–162, 1996
  42. Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies
    Statistics in Medicine, vol. 13, no. 2, pp. 153–162, 1994
  43. 53 mutation hotspot in radon-associated lung cancer
    The Lancet, vol. 343, no. 8906, pp. 1158–1159, 1994
  44. p53 mutation hotspot in radon-associated lung cancer
    The Lancet, vol. 343, no. 8889, pp. 86–87, 1994
  45. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese
    Pharmacogenetics, vol. 4, no. 4, pp. 185–192, 1994
  46. L-myc Proto-oncogene alleles and susceptibility to hepatocellular carcinoma
    International Journal of Cancer, vol. 54, no. 6, pp. 927–930, 1993
  47. Expression of CYP1A1 and CYP1A2 genes in human liver
    Pharmacogenetics, vol. 3, no. 5, pp. 239–249, 1993
  48. Statistical methods for assessing environmental effects on human genetic disorders
    Environmetrics, vol. 3, no. 4, pp. 369–384, 1992
  49. Evidence for clustering of amyotrophic lateral sclerosis in wisconsin
    Journal of Clinical Epidemiology, vol. 42, no. 6, pp. 569–575, 1989