Mouldy Sioud

Articles in Scholarly Journals [Incomplete List]

  1. Design of bifunctional siRNAs: Combining immunostimulation and gene-silencing in one single siRNA molecule
    Biochemical and Biophysical Research Communications, vol. 352, no. 3, pp. 642–649, 2007
  2. Gene Expression Analysis in Blood Cells in Response to Unmodified and 2'-Modified siRNAs Reveals TLR-dependent and Independent Effects
    Journal of Molecular Biology, vol. 365, no. 1, pp. 90–108, 2007
  3. Colon Cancer Cell-Derived Tumor Necrosis Factor-  Mediates the Tumor Growth-Promoting Response in Macrophages by Up-regulating the Colony-Stimulating Factor-1 Pathway
    Cancer Research, vol. 67, no. 3, pp. 1038–1045, 2007
  4. Molecular Basis for the Immunostimulatory Potency of Small Interfering RNAs
    Journal of Biomedicine and Biotechnology, vol. 2006, Article ID 23429, 4 pages, 2006
  5. RNA Interference
    Journal of Biomedicine and Biotechnology, vol. 2006, Article ID 89018, 2 pages, 2006
  6. RNAi Therapy: Antibodies guide the way
    Gene Therapy, vol. 13, no. 3, Article ID 3302634, 1 pages, 2006
  7. Signaling through Toll-like Receptor 7/8 Induces the Differentiation of Human Bone Marrow CD34+ Progenitor Cells along the Myeloid Lineage
    Journal of Molecular Biology, vol. 364, no. 5, pp. 945–954, 2006
  8. Innate sensing of self and non-self RNAs by Toll-like receptors
    Trends in Molecular Medicine, vol. 12, no. 4, pp. 167–176, 2006
  9. RNA interference below the immune radar
    Nature Biotechnology, vol. 24, no. 5, Article ID nbt0506-521, 1 pages, 2006
  10. Transcriptional targeting of small interfering RNAs into cancer cells
    Biochemical and Biophysical Research Communications, vol. 350, no. 4, pp. 854–859, 2006
  11. Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2'-hydroxyl uridines in immune responses
    European Journal of Immunology, vol. 36, no. 5, pp. 1222–1230, 2006
  12. Induction of Inflammatory Cytokines and Interferon Responses by Double-stranded and Single-stranded siRNAs is Sequence-dependent and Requires Endosomal Localization
    Journal of Molecular Biology, vol. 348, no. 5, pp. 1079–1090, 2005
  13. On the delivery of small interfering RNAs into mammalian cells
    Expert Opinion on Drug Delivery, vol. 2, no. 4, pp. 639–651, 2005
  14. Ribozymes, DNAzymes and Small Interfering RNAs as Therapeutics
    Current Drug Targets, vol. 6, no. 6, pp. 647–653, 2005
  15. Therapeutic potential of small interfering RNAs
    Drugs of the Future, vol. 29, no. 7, p. 741, 2004
  16. Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
    Oncogene, vol. 24, no. 7, Article ID 1208267, 14 pages, 2004
  17. Systematic identification of sense-antisense transcripts in mammalian cells
    Nature Biotechnology, vol. 22, no. 1, Article ID nbt925, 4 pages, 2004
  18. Colony-Stimulating Factor-1 Blockade by Antisense Oligonucleotides and Small Interfering RNAs Suppresses Growth of Human Mammary Tumor Xenografts in Mice
    Cancer Research, vol. 64, no. 15, pp. 5378–5384, 2004
  19. Therapeutic siRNAs
    Trends in Pharmacological Sciences, vol. 25, no. 1, pp. 22–28, 2004
  20. Gene Silencing by Systemic Delivery of Synthetic siRNAs in Adult Mice
    Journal of Molecular Biology, vol. 327, no. 4, pp. 761–766, 2003
  21. Cationic liposome-mediated delivery of siRNAs in adult mice
    Biochemical and Biophysical Research Communications, vol. 312, no. 4, pp. 1220–1225, 2003
  22. Selective targeting of cancer cells using synthetic peptides
    Drug Resistance Updates, vol. 6, no. 6, pp. 363–371, 2003
  23. Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
    European Journal of Immunology, vol. 33, no. 1, pp. 38–45, 2003
  24. Probing the Specificity of Human Myeloma Proteins with a Random Peptide Phage Library
    Scandinavian Journal of Immunology, vol. 57, no. 6, pp. 583–590, 2003
  25. Combination of Endostatin and a Protein Kinase Ca DNA Enzyme Improves the Survival of Rats with Malignant Glioma
    Neoplasia, vol. 4, no. 6, pp. 474–479, 2002
  26. Gene silencing in mammalian cells by preformed small RNA duplexes
    Biochemical and Biophysical Research Communications, vol. 295, no. 3, pp. 744–748, 2002
  27. Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
    European Journal of Immunology, vol. 31, no. 3, pp. 716–725, 2001
  28. An Anti-leukemic Single Chain Fv Antibody Selected from a Synthetic Human Phage Antibody Library
    Biochemical and Biophysical Research Communications, vol. 280, no. 2, pp. 548–552, 2001
  29. BMC Cell Biology, vol. 2, no. 1, p. 13, 2001
  30. Nucleic Acid Enzymes as a Novel Generation of Anti-gene Agents
    Current Molecular Medicine, vol. 1, no. 5, pp. 575–588, 2001
  31. Differential Expression of Bcl-2 Homologs in Human CD34+ Hematopoietic Progenitor Cells Induced to Differentiate into Erythroid or Granulocytic Cells
    Stem Cells, vol. 18, no. 4, pp. 261–272, 2000
  32. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy
    AIDS, vol. 14, no. 9, pp. F83–F93, 2000
  33. Therapeutic RNA and DNA enzymes
    Biochemical Pharmacology, vol. 60, no. 8, pp. 1023–1026, 2000
  34. Design of nuclease resistant protein kinase ca DNA enzymes with potential therapeutic application
    Journal of Molecular Biology, vol. 296, no. 3, pp. 937–947, 2000
  35. Protein Kinase Ca Isoform Regulates the Activation of the MAP Kinase ERK1/2 in Human Glioma Cells: Involvement in Cell Survival and Gene Expression
    Molecular Cell Biology Research Communications, vol. 4, no. 2, pp. 106–110, 2000
  36. Substitution of the 2'-Hydroxyl Group at Position 2.1 by an Amino Group Interferes with Mg2+ Binding and Efficient Cleavage by Hammerhead Ribozyme
    Biochemical and Biophysical Research Communications, vol. 262, no. 2, pp. 461–466, 1999
  37. High Cleavage Activity and Stability of Hammerhead Ribozymes with a Uniform 2'-Amino Pyrimidine Modification
    Biochemical and Biophysical Research Communications, vol. 250, no. 1, pp. 171–174, 1998
  38. A nuclease-resistant protein kinase Ca ribozyme blocks glioma cell growth
    Nature Biotechnology, vol. 16, no. 6, Article ID nbt0698-556, 5 pages, 1998
  39. A Minimised Hammerhead Ribozyme with Activity against Interleukin-2 in Human Cells,
    Biochemical and Biophysical Research Communications, vol. 231, no. 2, pp. 397–402, 1997
  40. Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates
    Nucleic Acids Research, vol. 25, no. 2, pp. 333–338, 1997
  41. Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-a production by peritoneal cellsin vitro andin vivo
    European Journal of Immunology, vol. 26, no. 5, pp. 1026–1031, 1996
  42. Enhancement of Hammerhead Ribozyme Catalysis by Glyceraldehyde-3-phosphate Dehydrogenase
    Journal of Molecular Biology, vol. 257, no. 4, pp. 775–789, 1996
  43. Selection of Ligands for Polyclonal Antibodies from Random Peptide Libraries: Potential Identification of (Auto)Antigens That May Trigger B and T Cell Responses in Autoimmune Diseases
    Clinical Immunology and Immunopathology, vol. 79, no. 2, pp. 105–114, 1996
  44. Structural Characterization of Peptides That Bind Synovial Fluid Antibodies from RA Patients: A Novel Strategy for Identification of Disease-Related Epitopes Using a Random Peptide Library
    Clinical Immunology and Immunopathology, vol. 75, no. 1, pp. 45–50, 1995
  45. Freshly Isolated Tumour-Infiltrating T-Lymphocytes have a High Cytotoxic Potential, as Measured by their Ability to Induce Apoptosis in the Target Cell
    Scandinavian Journal of Immunology, vol. 41, no. 1, pp. 42–48, 1995
  46. Three New Cross-Reacting Idiotopes as Markers for the Products of Two Distinct Human VH3 Genes Expressed in the Early Repertoire
    Scandinavian Journal of Immunology, vol. 40, no. 6, pp. 681–690, 1994
  47. Interaction Between Tumour Necrosis Factor a Ribozyme and Cellular Proteins Involvement in Ribozyme Stability and Activity
    Journal of Molecular Biology, vol. 242, no. 5, pp. 619–629, 1994
  48. Selective activation of resting human ?d T lymphocytes by interleukin-2
    European Journal of Immunology, vol. 23, no. 9, pp. 2092–2099, 1993
  49. Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
    European Journal of Immunology, vol. 23, no. 12, pp. 3189–3193, 1993
  50. Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid
    European Journal of Immunology, vol. 22, no. 5, pp. 1315–1322, 1992
  51. Limited heterogeneity of T cell receptor variable region gene usage in juvenile rheumatoid arthritis synovial T cells
    European Journal of Immunology, vol. 22, no. 9, pp. 2413–2418, 1992
  52. Preformed ribozyme destroys tumour necrosis factor mRNA in human cells
    Journal of Molecular Biology, vol. 223, no. 4, pp. 831–835, 1992
  53. Spontaneous In Vivo Gene Transcription of Interleukin-2, Interleukin-3, Interleukin-4, Interleukin-6, Interferon-Gamma, Interleukin-2 Receptor (CD25) and Proto-Oncogene c-myc by Rheumatoid Synovial T Lymphocytes
    Scandinavian Journal of Immunology, vol. 36, no. 6, pp. 865–874, 1992
  54. Immune Responses to 6 and 30-kDa Mycobacterial Antigens in Rheumatoid Patients, and Vbeta Usage by Specific Synovial T-Cell Lines and Fresh T Cells
    Scandinavian Journal of Immunology, vol. 34, no. 6, pp. 803–812, 1991
  55. T cell receptor d diversity of freshly isolated T lymphocytes in rheumatoid synovitis
    European Journal of Immunology, vol. 21, no. 1, pp. 239–241, 1991
  56. The Vdelta Gene Usage by Freshly Isolated T Lymphocytes from Synovial Fluids in Rheumatoid Synovitis: a Preliminary Report
    Scandinavian Journal of Immunology, vol. 31, no. 4, pp. 415–421, 1990