Andreas G. Tzakos0000-0001-6391-0288
Andreas G. Tzakos obtained his Ph.D. degree (2004) at the Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, Greece. During this period, he received numerous awards and fellowships (EMBO, FEBS, Marie Curie, NATO, Greek State Scholarship Foundation) and trained in Florence (CERM) and Utrecht (SON NMR) in multidimensional NMR techniques. In 2004, he received the Leonidas Zervas Award. After postdoctoral research as an EMBO Fellow at the MRC Laboratory of Molecular Biology (Cambridge, UK), he is currently (since 2009) a Lecturer at the Department of Chemistry, University of Ioannina, Greece. The same year, he became a member of the interscience molecular oncology lab (iMOL) of the Cancer Biobank Center of the University of Ioannina, which is a member of the European Biobanking and Biomolecular Resources Research Infrastructures. He is also a Committee Member of the NMR Center of the University of Ioannina that belongs to the Network of Horizontal Laboratory Units. He has authored more than 30 research articles in the field of (a) structural biology (NMR), (b) rational design, synthesis and biological evaluation of bioactive peptides, plant-derived natural products, and small bioactive molecules targeting pharmaceutically important receptors, (c) biocatalysis, and (d) network pharmacology. He has also filled a priority UK patent application with MRCT, LMB, Cambridge on novel, and selective AT2R analogues. His current interests include decoding the molecular mechanisms, which underlie cancer development using multidisciplinary approaches in the interfaces of chemistry, biology, and medicine. To this, we utilize modern NMR methodologies complemented by numerous biophysical (fluorescence, CD, ITC, DSC) and bioinformatic techniques to characterize the dynamic, structural, and thermodynamic properties of the studied systems as also their interactions.
Biography Updated on 4 April 2012