Yuzhuo Wang obtained his B.S. degree from Nankai University, received the Ph.D. degree from the University of Hong Kong in 1997, and held a postdoctoral fellow position at the University of California, San Francisco, Calif, USA (1997–2000). He has a dual appointment as a Senior Scientist at the Vancouver Prostate Centre and the BC Cancer Agency, Canada. Dr. Wang is also the Leader of the Living Tumor Laboratory and an Associate Professor at the University of British Columbia. In addition to proposing novel hypotheses on “prostate stem cells” and “epithelial-immune cell transition (EIT)”, Dr. Wang is recognized for his pioneering work in the field of prostate cancer modeling, he was the first to establish tissue recombination model of hormonal prostatic carcinogenesis. He also developed the first model of hormonal carcinogenesis in a human prostatic epithelium. Dr. Wang is responsible for a novel method for establishing transplantable, patient-derived xenograft models that closely resemble patients’ malignancies. So far, the group has developed over 150 transplantable tumor lines in the Living Tumor Laboratory. More importantly, such xenograft models have been effectively applied in a number of translational research areas, such as (i) preclinical drug efficacy studies in anticancer therapeutics development, (ii) discovery and validation of potential biomarkers and/or therapeutic targets, and (iii) personalized cancer therapy. Dr. Wang has received a number of awards for his academic achievements, such as the Translation Research Award from Roche, the Overseas Chinese Scholars Award, and the Innovative Scholar Award from the International Cancer Alliance for Research and Education.
Biography Updated on 14 April 2011