Rona Ruth Ramsay

Articles in Scholarly Journals [Incomplete List]

  1. Variations in activity and inhibition with pH: the protonated amine is the substrate for monoamine oxidase, but uncharged inhibitors bind better
    Journal of Neural Transmission, vol. 114, no. 6, pp. 707–712, 2007
  2. Interactions of imidazoline ligands with the active site of purified monoamine oxidase A
    FEBS Journal, vol. 274, no. 6, pp. 1567–1575, 2007
  3. Journal of Medicinal Chemistry, vol. 48, no. 2, pp. 499–506, 2005
  4. Orientation of oxazolidinones in the active site of monoamine oxidase
    Biochemical Pharmacology, vol. 70, no. 3, pp. 407–416, 2005
  5. Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines
    Bioorganic & Medicinal Chemistry, vol. 13, no. 10, pp. 3487–3495, 2005
  6. The G553M Mutant of Peroxisomal Carnitine Octanoyltransferase Catalyses Acetyl Transfer and Acetyl-CoA Hydrolysis
    Monatshefte für Chemie - Chemical Monthly, vol. 136, no. 8, pp. 1341–1347, 2005
  7. Conformational changes in monoamine oxidase A in response to ligand binding or reduction
    Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1672, no. 1, pp. 60–66, 2004
  8. Carnitine acyltransferases and their influence on CoA pools in health and disease
    Molecular Aspects of Medicine, vol. 25, no. 5-6, pp. 475–493, 2004
  9. A Stable Tyrosyl Radical in Monoamine Oxidase A
    Journal of Biological Chemistry, vol. 280, no. 6, pp. 4627–4631, 2004
  10. Interactions of D-amphetamine with the active site of monoamine oxidase-A
    Inflammopharmacology, vol. 11, no. 2, pp. 127–133, 2003
  11. Monoamine Oxidases: to Inhibit or Not to Inhibit
    Mini Reviews in Medicinal Chemistry, vol. 3, no. 2, pp. 129–136, 2003
  12. A snapshot of carnitine acetyltransferase
    Trends in Biochemical Sciences, vol. 28, no. 7, pp. 343–346, 2003
  13. Monoamine oxidase A inhibitory potency and flavin perturbation are influenced by different aspects of pirlindole inhibitor structure
    Biochemical Pharmacology, 2003
  14. Inhibitors alter the spectrum and redox properties of monoamine oxidase A
    Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, vol. 1601, no. 2, pp. 178–184, 2002
  15. Molecular enzymology of carnitine transfer and transport
    Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol. 1546, no. 1, pp. 21–43, 2001
  16. The Role of the Carnitine System in Peroxisomal Fatty Acid Oxidation
    The American Journal of the Medical Sciences, vol. 318, no. 1, p. 28, 1999
  17. Monoamine Oxidase Contains a Redox-active Disulfide
    Journal of Biological Chemistry, vol. 273, no. 23, pp. 14074–14076, 1998
  18. Characteristics of -carnitine transport by lactating rat mammary tissue
    Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol. 1393, no. 1, pp. 49–56, 1998
  19. Inhibition of Monoamine Oxidase A by ß-Carboline Derivatives
    Archives of Biochemistry and Biophysics, vol. 337, no. 1, pp. 137–142, 1997
  20. Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds
    Journal of Biochemical Toxicology, vol. 11, no. 1, pp. 33–43, 1996
  21. Inhibitor Probes of the Quinone Binding Sites of Mammalian Complex II and Escherichia coli Fumarate Reductase
    Journal of Biological Chemistry, vol. 271, no. 35, pp. 21020–21024, 1996
  22. Syntheses, Structures, and Enzymic Evaluations of Conformationally Constrained, Analog Inhibitors of Carnitine Acetyltransferase: (2R,6R)-, (2S,6S)-, (2R,6S)-, and (2S,6R)-6-(Carboxylatomethyl)-2-(hydroxymethyl)-2,4,4-trimethylmorpholinium
    The Journal of Organic Chemistry, vol. 60, no. 21, pp. 6688–6695, 1995
  23. Dramatic Species Differences in the Susceptibility of Monoamine Oxidase B to a Group of Powerful Inhibitors
    Biochemical and Biophysical Research Communications, vol. 206, no. 2, pp. 556–562, 1995
  24. Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol. 1271, no. 1, pp. 211–219, 1995
  25. Evaluation of (2S,4S)/(2R,4R) and (2S,4R)/(2R,4S) 6,6-N,N-dimethyl-2-methyl-2-oxo-1,3-dioxa-4-hexadecyl-6,aza-2-phosphacyclooctane bromide as inhibitors for protein kinase C, carnitine octanoyltransferase, and carnitine palmitoyltransferase
    Bioorganic & Medicinal Chemistry Letters, vol. 4, no. 7, pp. 883–886, 1994
  26. The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase
    Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol. 1187, no. 2, pp. 198–202, 1994
  27. Biochemistry, vol. 32, no. 20, pp. 5490–5490, 1993
  28. Oxidation of tetrahydrostilbazole by monoamine oxidase A demonstrates the effect of alternate pathways in the kinetic mechanism
    Biochemistry, vol. 32, no. 35, pp. 9025–9030, 1993
  29. Biochemistry, vol. 32, no. 9, pp. 2137–2143, 1993
  30. The Carnitine Acyltransferases and Their Role in Modulating Acyl-CoA Pools
    Archives of Biochemistry and Biophysics, vol. 302, no. 2, pp. 307–314, 1993
  31. Journal of Medicinal Chemistry, vol. 36, no. 2, pp. 237–242, 1993
  32. Reactivation of NADH Dehydrogenase (Complex I) Inhibited by 1-Methyl-4-(4'-Alkylphenyl)pyridinium Analogues: A Clue to the Nature of the Inhibition Site
    Journal of Neurochemistry, vol. 61, no. 4, pp. 1546–1548, 1993
  33. Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoraductase by rotenone, piericidin A, and MPP
    Biochemical and Biophysical Research Communications, vol. 189, no. 1, pp. 47–52, 1992
  34. Journal of Organic Chemistry, vol. 57, no. 12, pp. 3426–3431, 1992
  35. Biochemistry, vol. 30, no. 18, pp. 4624–4629, 1991
  36. Interaction of 1-Methyl-4-Phenylpyridinium Ion (MPP+) and Its Analogs with the Rotenone/Piericidin Binding Site of NADH Dehydrogenase
    Journal of Neurochemistry, vol. 56, no. 4, pp. 1184–1190, 1991
  37. A new class of powerful inhibitors of monoamine oxidase A
    Biochemical and Biophysical Research Communications, vol. 172, no. 3, pp. 1338–1341, 1990
  38. Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone
    Biochemical and Biophysical Research Communications, vol. 169, no. 1, pp. 123–128, 1990
  39. Mechanism of the neurotoxicity of MPTP An update
    FEBS Letters, vol. 274, no. 1-2, pp. 1–8, 1990
  40. Enhancement by tetraphenylboron of the interaction of the 1-methyl-4-phenylpyridinium ion (MPP+) with mitochondria
    Biochemical and Biophysical Research Communications, vol. 159, no. 3, pp. 983–990, 1989
  41. effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria
    Archives of Biochemistry and Biophysics, vol. 273, no. 2, pp. 449–457, 1989
  42. Oxidation of Analogs of l-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Monoamine Oxidases A and B and the Inhibition of Monoamine Oxidases by the Oxidation Products
    Journal of Neurochemistry, vol. 53, no. 6, pp. 1837–1842, 1989
  43. Structural Dependence of the Inhibition of Mitochondrial Respiration and of NADH Oxidase by 1-methyl-4-phenylpyridinium (MPP+) Analogs and their Energized Accumulation by Mitochondria
    Proceedings of the National Academy of Sciences, vol. 86, no. 23, pp. 9168–9172, 1989
  44. Mechanism of the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP)+, the toxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    Toxicology, vol. 49, no. 1, pp. 17–23, 1988
  45. A case of carnitine palmitoyltransferase II deficiency in human skeletal muscle
    FEBS Letters, vol. 241, no. 1-2, pp. 126–130, 1988
  46. Inhibition of NADH oxidation by pyridine derivatives
    Biochemical and Biophysical Research Communications, vol. 146, no. 1, pp. 53–60, 1987
  47. The inhibition site of MPP, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase
    Archives of Biochemistry and Biophysics, vol. 259, no. 2, pp. 645–649, 1987
  48. Biochemistry, vol. 26, no. 11, pp. 3045–3050, 1987
  49. Biochemical Events in the Development of Parkinsonism Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine
    Journal of Neurochemistry, vol. 49, no. 1, pp. 1–8, 1987
  50. Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+
    Biochemical and Biophysical Research Communications, vol. 134, no. 2, pp. 743–748, 1986
  51. Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism
    Biochemical and Biophysical Research Communications, vol. 135, no. 1, pp. 269–275, 1986
  52. Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP
    Life Sciences, vol. 39, no. 7, pp. 581–588, 1986
  53. Biochemistry, vol. 20, no. 26, pp. 7476–7482, 1981
  54. Reaction Site of Carboxanilides and of Thenoyltrifluoroacetone in Complex II
    Proceedings of the National Academy of Sciences, vol. 78, no. 2, pp. 825–828, 1981
  55. The Effects of Temperature and Some Inhibitors an the Carnitine Exchange System of Heart Mitochondria
    European Journal of Biochemistry, vol. 69, no. 1, pp. 299–303, 1976