Eng-Ang Ling works as a Professor at the Department of Anatomy, National University of Singapore (NUS). He gained his B.S. degree from Taiwan; a Ph.D. degree from Cambridge; a D.S. degree from Singapore. From 1998 and 2008, he worked as the Head of the Department of Anatomy, NUS. His research interest is on the origin, development, and roles of microglial cells in neuroinflammation. A major research finding was the experimental demonstration that amoeboid microglia in the developing brain are derived from blood monocytes; another finding was the transformation of amoeboid microglia into ramified microglia that persist through the adulthood. His current research interests are on expression and trans-regulation of Notch-1 and NFkB signaling in activated microglia as well as the expression of Kv1.1/1. 2, COX 1/2, NG2, and sphingosine kinase 1 in activated microglia in neurodegeneration in the brain and retina. He has more than 35 years of teaching experience in histology and gross (regional) anatomy.
Biography Updated on 23 December 2009