Professor Sherry Voytik-Harbin holds an Honors BS degree in Chemistry from Indiana University as well as a MS degree in Electrical Engineering and PhD in Veterinary Physiology and Pharmacology from Purdue University. At present, she holds an Associate Professor rank at Purdue University with appointments within the Weldon School of Biomedical Engineering and Department of Basic Medical Sciences. Voytik-Harbin has an extensive history of translational research related to tissue-derived extracellular matrices and now more recently engineered three-dimensional collagen matrices. Her laboratory has focused on defining how non-traditional collagen polymer building blocks, specified by their intermolecular cross-link composition, impact the molecular packing of collagen and can be used to reproducibly control relevant fibril-level design features of collagen-based matrices. In turn, the cross-link chemistries and the fibril microstructures work together to dictate functional matrix-level physical properties including matrix stiffness, fluid transport, and proteolytic degradation, which are known to guide cell fate (lineage specific differentiation of stem cells) and tissue morphogenesis (lumenized vessel network formation) in vitro and in vivo.
Biography Updated on 13 August 2012