Laurence S. Romsted
Laurence S. Romsted received an A. B. degree from DePauw University, Greencastle, IN, USA a Ph.D. degree from Indiana University, and a Postdoctoral degree from the University of California at Santa Barbara. He serves as a Professor of chemistry, Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey. His research applies physical organic and bioorganic approaches to problems in association colloid chemistry and emulsions. He studies amphiphile aggregate effects on chemical reactivity and use chemical reactions to better understand aggregate structures. UV/Visible, Fluorescence, FTIR, and NMR spectroscopies and HPLC are used in concert with chemical reactivity studies to obtain information on delicate balance of forces that control the formation and stabilities of aggregates and the association of ions and molecules to their surfaces. His group developed the chemical trapping method based on the heterolytic chemistry of an arenediazonium ion probe to determine, simultaneously, the concentrations of water and a variety of other weakly basic nucleophiles at aggregate interfaces including, alcohols, counterions, peptide bonds, urea, and surfactant head groups. New protocols for the method are being developed to determine polypeptide topologies at aggregate interfaces. Recent work demonstrates that the formation of rod-like aggregates is accompanied by specific ion pairing and dehydration of the interfacial region of the aggregates which permits tighter packing of the amphiphiles and formation of rod-like structures. The results should enhance understanding of the relations between the structure and composition and the ion binding properties of biomembranes. The probe is also being used to estimate antioxidant distributions between the oil, interfacial, and aqueous regions of opaque emulsions.
Biography Updated on 27 October 2010