Yidong Chen
Yidong Chen received his B.S. and M.S.
degrees in electrical engineering from Fudan
University, Shanghai, China, in 1983
and 1986, respectively, and Ph.D. degree in
imaging science from Rochester Institute of
Technology, Rochester, NY, in 1995. From
1986 to 1988, he joined the Department of
Electronic Engineering of Fudan University
as an Assistant Professor. During 1988 to
1989, he was a Visiting Scholar at the Department
of Computer Engineering, Rochester Institute of Technology.
From 1995 to 1996, He joined Hewlett Packard Company
as a Research Engineer, specialized in digital halftoning and color
image processing. Since 1996, he joined microarray technology development
effort at the National Human Genome Research Institute,
National Institutes of Health, Bethesda, Md, as a Staff Scientist
for microarray image analysis and bioinformatics. Currently, he is
an Associate Investigator at Cancer Genetics Branch of the National
Human Genome Research Institute. His research interests include
bioinformatics, biostatistics in genomic research, genetic data visualization,
analysis and management, genetic network modeling,
and biomedical image processing.
Biography Updated on 18 May 2006
Articles in Scholarly Journals [Incomplete List]
- Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression ofTRMT12 in breast cancer
Genes, Chromosomes and Cancer, vol. 46, no. 7, pp. 694–707, 2007 - Sensitive and specific method for detecting G protein–coupled receptor mRNAs
Nature Methods, vol. 4, no. 1, Article ID nmeth977, 2 pages, 2007 - Gene Expression Profiling Reveals Potential Biomarkers of Human Hepatocellular Carcinoma
Clinical Cancer Research, vol. 13, no. 4, pp. 1133–1139, 2007 - Normalization Benefits Microarray-Based Classification
EURASIP Journal on Bioinformatics and Systems Biology, vol. 2006, Article ID 43056, 13 pages, 2006 - Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
Cancer Cell, vol. 10, no. 2, pp. 99–111, 2006 - Identification of molecular markers for endometriosis in blood lymphocytes by using deoxyribonucleic acid microarrays
Fertility and Sterility, vol. 85, no. 6, pp. 1676–1683, 2006 - Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)
Genome Research, vol. 16, no. 1, pp. 123–131, 2005 - Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
Oncogene, vol. 24, no. 23, Article ID 1208518, 5 pages, 2005 - Optimal robust classifiers
Pattern Recognition, vol. 38, no. 10, pp. 1520–1532, 2005 - Gene Expression Profiling of Human Sarcomas: Insights into Sarcoma Biology
Cancer Research, vol. 65, no. 20, pp. 9226–9235, 2005 - Editorial
EURASIP Journal on Applied Signal Processing, vol. 2004, no. 1, pp. 3–4, 2004 - The Local Maximum Clustering Method and Its Application in Microarray Gene Expression Data Analysis
EURASIP Journal on Applied Signal Processing, vol. 2004, no. 1, pp. 53–63, 2004 - Noise factor analysis for cDNA microarrays
Journal of Biomedical Optics, vol. 9, no. 4, p. 663, 2004 - Cancer-associated molecular signature in the tissue samples of patients with cirrhosis
Hepatology, vol. 39, no. 2, pp. 518–527, 2004 - Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer
Nature Genetics, vol. 36, no. 9, Article ID ng1408, 4 pages, 2004 - Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome
Oncogene, vol. 23, no. 12, Article ID 1207337, 10 pages, 2004 - Defective Immune Function of Primary Effusion Lymphoma Cells is Associated with Distinct KSHV Gene Expression Profiles
Leukemia & Lymphoma, vol. 45, no. 6, pp. 1223–1238, 2004 - Which is better for cDNA-microarray-based classification: ratios or direct intensities
Bioinformatics, vol. 20, no. 16, pp. 2513–2520, 2004 - Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease
Human Molecular Genetics, vol. 12, no. 17, pp. 2191–2199, 2003 - Molecular classification of familial non-BRCA1/BRCA2 breast cancer
Proceedings of the National Academy of Sciences, vol. 100, no. 5, pp. 2532–2537, 2003 - Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
Nature Medicine, vol. 9, no. 4, Article ID nm843, 7 pages, 2003 - Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice
EMBO Reports, vol. 4, no. 6, Article ID embor862, 6 pages, 2003 - Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis
The Prostate, vol. 51, no. 3, pp. 189–200, 2002 - Mutation of melanosome protein RAB38 in chocolate mice
Proceedings of the National Academy of Sciences, vol. 99, no. 7, pp. 4471–4476, 2002 - Inference from Clustering with Application to Gene-Expression Microarrays
Journal of Computational Biology, vol. 9, no. 1, pp. 105–126, 2002 - Assessing the significance of consistently mis-regulated genes in cancer associated gene expression matrices
Bioinformatics, vol. 18, no. 3, pp. 389–394, 2002 - Ratio statistics of gene expression levels and applications to microarray data analysis
Bioinformatics, vol. 18, no. 9, pp. 1207–1215, 2002 - Amine-modified random primers to label probes for DNA microarrays
Nature Biotechnology, vol. 20, no. 7, Article ID nb0702-738, 4 pages, 2002 - Simulation of cDNA microarrays via a parameterized random signal model
Journal of Biomedical Optics, vol. 7, no. 3, p. 507, 2002 - Journal of Biological Systems, vol. 10, no. 4, p. 337, 2002
- Transcription Program of Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus)
Journal of Virology, vol. 75, no. 10, pp. 4843–4853, 2001 - Gene-Expression Profiles in Hereditary Breast Cancer
New England Journal of Medicine, vol. 344, no. 8, pp. 539–548, 2001 - Robust optimal granulometric bandpass filters
Signal Processing, vol. 81, no. 7, pp. 1357–1372, 2001 - Multivariate Measurement of Gene Expression Relationships
Genomics, vol. 67, no. 2, pp. 201–209, 2000 - Positional Cloning Utilizing Genomic DNA Microarrays: The Niemann–Pick Type C Gene as a Model System
Molecular Genetics and Metabolism, vol. 70, no. 1, pp. 10–18, 2000 - Identification of Tumor-Suppressor Genes Using Human Melanoma Cell Lines UACC903, UACC903(+6), and SRS3 by Comparison of Expression Profiles
Molecular Carcinogenesis, vol. 28, no. 2, pp. 119–127, 2000 - cDNA microarray technology and its applications
Biotechnology Advances, vol. 18, no. 1, pp. 35–46, 2000 - Nature, vol. 406, no. 6795, pp. 536–540, 2000
- Detecting Activation of Ribosomal Protein S6 Kinase by Complementary DNA and Tissue Microarray Analysis
Journal of the National Cancer Institute, vol. 92, no. 15, pp. 1252–1259, 2000 - General nonlinear framework for the analysis of gene interaction via multivariate expression arrays
Journal of Biomedical Optics, vol. 5, no. 4, p. 411, 2000 - Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis
Proceedings of the National Academy of Sciences, vol. 96, no. 16, pp. 9277–9280, 1999 - Hormone Therapy Failure in Human Prostate Cancer: Analysis by Complementary DNA and Tissue Microarrays
Journal of the National Cancer Institute, vol. 91, no. 20, pp. 1758–1764, 1999 - Expression profiling using cDNA microarrays
Nature Genetics, vol. 21, Article ID 4434, 4 pages, 1999 - Expression profiling in cancer using cDNA microarrays
Electrophoresis, vol. 20, no. 2, pp. 223–229, 1999 - Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses
Oncogene, vol. 18, no. 24, pp. 3666–3672, 1999 - Logical structural filters
Optical Engineering, vol. 37, no. 6, p. 1668, 1998 - Optimal and adaptive reconstructive granulometric bandpass filters
Signal Processing, vol. 61, no. 1, pp. 65–81, 1997 - Bayesian morphological peak estimation and its application to chromosome counting via fluorescence In situ hybridization
Pattern Recognition, vol. 29, no. 6, pp. 987–996, 1996 - Adaptive reconstructive tau-openings: convergence and the steady-state distribution
Journal of Electronic Imaging, vol. 5, no. 3, p. 266, 1996 - Gray-scale morphological granulometric texture classification
Optical Engineering, vol. 33, no. 8, p. 2713, 1994 - Estimation of optimal morphological t-opening parameters based on independent observation of signal and noise pattern spectra
Signal Processing, vol. 29, no. 3, pp. 265–281, 1992