Silvia Siso served as a Veterinary Pathologist by 12-year training. Her main research interest is to gain understanding into the pathophysiology of animal infectious diseases, focusing on those diseases that involve the central and peripheral nervous systems. She did her Ph.D. degree (1998- 2002, Barcelona, Spain) in comparative neuropathology. After her early postdoctoral experience (2002-2004, Bern, Switzerland), she gained more interest in investigating the spatial and temporal molecular neuropathology underlying neurological disorders of domestic animals. At present, her topics of interest include zoonoses that can be studied mainly in sheep and rodents. Her current research in prion disorders aims to understand (i) host genetics and host-pathogen interaction for strain viability and stability in animal prion diseases, (ii) mechanisms of neuroinvasion, CNS spread, and extra-CNS drainage of infectivity in infectious diseases, and (iii) elicit the neuroimmunomodulatory responses evolving from degenerative diseases of the CNS that contribute to neuronal loss and clinical onset of disease. Technical skills include stereomicroscope dissection, histological staining methods, immunohistochemistry, and biochemical techniques.
Biography Updated on 30 November 2010