Hans Knecht from Zurich Medical School, Zurich, Switzerland, and performed fellowships in haematopathology with Karl Lennert and in Clinical Haematology with Maxime Seligmann. Since 2005 he is Professor of Medicine at the University of Sherbrooke, Québec, Canada, and Acting Director of the Haematology Laboratory. He is an attending physician at the haematology department, academic teacher, clinical investigator, and member of two grant-reviewing committees. From 2000 to 2005, Knecht was the Director of the Swiss Paraplegic Research with construction of an advanced reseach institute. Over the past 20 years, Knecht laboratory for translational research built up a strong reputation in lymphoma biology, in particular prelymphomatous states, angioimmunoblastic T-cell lymphoma, Hodgkin's disease, and the disease promoting activities of the Epstein-Barr virus encoded LMP1 (latent membrane 1) oncoprotein. Currently the laboratory focuses on the molecular events leading to the transition from the mononuclear Hodgkin to the multinuclear Reed-Sternberg cell. In collaboration with the Mai laboratory at MICB of the University of Manitoba, Winnipeg, MB, Canada, the Wellinger Laboratory, and the Department of Pahology at the University of Sherbrooke, Knecht laboratory discovered a major impact of the 3D nuclear telomere organization on this transformation. Research of 3D telomere dynamics in primary progressive or relapsing diseasse is under way. Knecht laboratoy has published over 100 manuscripts in first rated haematology and onclogy journals.
Biography Updated on 19 December 2010