James Alexander

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http://spider.science.strath.ac.uk/sipbs/staff/staffDetails.php?u=j.alexander

Articles in Scholarly Journals [Incomplete List]

  1. Interleukin-18 enhances a Th2 biased response and susceptibility to Leishmania mexicana in BALB/c mice
    Microbes and Infection, vol. 10, no. 7, pp. 834–839, 2008
  2. Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors
    Immunology, vol. 125, no. 1, pp. 59–69, 2008
  3. Neutrophils Contribute to Development of a Protective Immune Response during Onset of Infection with Leishmania donovani
    Infection and Immunity, vol. 76, no. 2, pp. 532–541, 2007
  4. Deletion of IL-4Rα on CD4 T Cells Renders BALB/c Mice Resistant to Leishmania major Infection
    PLoS Pathogens, vol. 3, no. 5, p. e68, 2007
  5. Ocular toxoplasmosis: in the storm of the eye
    Parasite Immunology, vol. 28, no. 12, pp. 635–642, 2006
  6. Oral delivery of tetanus toxoid using vesicles containing bile salts (bilosomes) induces significant systemic and mucosal immunity
    Methods, vol. 38, no. 2, pp. 90–95, 2006
  7. T helper (h)1/Th2 and : paradox rather than paradigm
    Immunology Letters, vol. 99, no. 1, pp. 17–23, 2005
  8. Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection*
    Parasite Immunology, vol. 27, no. 5, pp. 171–180, 2005
  9. Toxoplasma gondii-Specific Immunoglobulin M Limits Parasite Dissemination by Preventing Host Cell Invasion
    Infection and Immunity, vol. 73, no. 12, pp. 8060–8068, 2005
  10. Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?
    Immunological Reviews, vol. 201, no. 1, pp. 206–224, 2004
  11. Intestinal pathology during acute toxoplasmosis is IL-4 dependent and unrelated to parasite burden
    Parasite Immunology, vol. 26, no. 2, pp. 75–82, 2004
  12. Cysteine peptidases as virulence factors of
    Current Opinion in Microbiology, vol. 7, no. 4, pp. 375–381, 2004
  13. Optimisation of a lipid based oral delivery system containing A/Panama influenza haemagglutinin
    Vaccine, vol. 22, no. 19, pp. 2425–2429, 2004
  14. Protection against the Early Acute Phase of Cryptosporidium parvum Infection Conferred by Interleukin-4-Induced Expression of T Helper 1 Cytokines
    The Journal of Infectious Diseases, vol. 190, no. 5, pp. 1019–1025, 2004
  15. Pinpointing IL-4-independent acquisition and IL-4-influenced maintenance of Th2 activity by CD4 T cells
    European Journal of Immunology, vol. 34, no. 3, pp. 686–694, 2004
  16. Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12
    Immunology, vol. 108, no. 2, pp. 137–143, 2003
  17. Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses
    Nature Medicine, vol. 9, no. 10, Article ID nm933, 5 pages, 2003
  18. DNA vaccination with the immunodominant tachyzoite surface antigen (SAG-1) protects against adult acquired Toxoplasma gondii infection but does not prevent maternofoetal transmission
    Vaccine, vol. 21, no. 21-22, pp. 2813–2820, 2003
  19. Expression of Multiple CPB Genes Encoding Cysteine Proteases Is Required for Leishmania mexicana Virulence In Vivo
    Infection and Immunity, vol. 71, no. 6, pp. 3190–3195, 2003
  20. Both Interleukin-4 (IL-4) and IL-4 Receptor   Signaling Contribute to the Development of Hepatic Granulomas with Optimal Antileishmanial Activity
    Infection and Immunity, vol. 71, no. 8, pp. 4804–4807, 2003
  21. An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection
    European Journal of Immunology, vol. 32, no. 10, pp. 2923–2933, 2002
  22. Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes)
    Vaccine, vol. 19, no. 20-22, pp. 2965–2974, 2001
  23. Counter-Protective Role for Interleukin-5 during Acute Toxoplasma gondii Infection
    Infection and Immunity, vol. 69, no. 2, pp. 1044–1052, 2001
  24. Immunological Studies of Chronic Ocular Toxoplasmosis: Up-Regulation of Major Histocompatibility Complex Class I and Transforming Growth Factor beta and a Protective Role for Interleukin-6
    Infection and Immunity, vol. 69, no. 4, pp. 2589–2595, 2001
  25. Sex-Associated Hormones and Immunity to Protozoan Parasites
    Clinical Microbiology Reviews, vol. 14, no. 3, pp. 476–488, 2001
  26. The CD40/CD40 Ligand Interaction Is Required for Resistance to Toxoplasmic Encephalitis
    Infection and Immunity, vol. 68, no. 3, pp. 1312–1318, 2000
  27. Presence of Phosphorylcholine on a Filarial Nematode Protein Influences Immunoglobulin G Subclass Response to the Molecule by an Interleukin-10-Dependent Mechanism
    Infection and Immunity, vol. 68, no. 9, pp. 5466–5468, 2000
  28. Protective immunity to erythrocytic Plasmodium chabaudi AS infection involves IFNγ-mediated responses and a cellular infiltrate to the liver
    Parasitology, vol. 121, no. 5, pp. 473–482, 2000
  29. Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis
    European Journal of Immunology, vol. 30, no. 10, pp. 2935–2943, 2000
  30. Regulation of macrophage IL-12 synthesis byLeishmania phosphoglycans
    European Journal of Immunology, vol. 29, no. 1, pp. 235–244, 1999
  31. Neither interleukin-6 nor signalling via tumour necrosis factor receptor-1 contribute to the adjuvant activity of Alum and Freund's adjuvant
    Immunology, vol. 93, no. 1, pp. 41–48, 1998
  32. A protective role for IL-6 during early infection with Toxoplasma gondii
    Parasite Immunology, vol. 20, no. 5, pp. 231–239, 1998
  33. Sex-determined resistance against Leishmania mexicana is associated with the preferential induction of a Th1-like response and IFN-gamma production by female but not male DBA/2 mice
    Immunology and Cell Biology, vol. 76, no. 2, pp. 159–166, 1998
  34. The role of IL-4 in adult acquired and congenital toxoplasmosis
    International Journal for Parasitology, vol. 28, no. 1, pp. 113–120, 1998
  35. Mechanisms of innate resistance to Toxoplasma gondii infection
    Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 352, no. 1359, pp. 1355–1359, 1997
  36. Immune responses in mice induced by HSV-1 glycoproteins presented with ISCOMs or NISV delivery systems
    Vaccine, vol. 14, no. 17-18, pp. 1581–1589, 1996
  37. Lipid vesicle-entrapped influenza A antigen modulates the influenza A-specific human antibody response in immune reconstituted SCID-human mice
    European Journal of Immunology, vol. 26, no. 7, pp. 1664–1667, 1996
  38. In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production
    European Journal of Immunology, vol. 26, no. 9, pp. 2062–2066, 1996
  39. Comparison of the phosphofructokinase and pyruvate kinase activities of Cryptosporidium parvum, Eimeria tenella and Toxoplasma gondii
    Molecular and Biochemical Parasitology, vol. 76, no. 1-2, pp. 23–29, 1996
  40. Sex steroids, pregnancy-associated hormones and immunity to parasitic infection
    Parasitology Today, vol. 12, no. 10, pp. 382–388, 1996
  41. Accurate determination of adjuvant-associated protein or peptide by ninhydrin assay
    Vaccine, vol. 13, no. 15, pp. 1441–1444, 1995
  42. Antibody responses toToxoplasma gondii antigen in human peripheral blood lymphocyte-reconstituted severe-combined immunodeficient mice reproduce the immunological status of the lymphocyte donor
    European Journal of Immunology, vol. 25, no. 5, pp. 1426–1430, 1995
  43. Congenital toxoplasmosis in the Balb/c mouse: prevention of vertical disease transmission and fetal death by vaccination
    Vaccine, vol. 12, no. 15, pp. 1389–1394, 1994
  44. Studies on the adjuvant activity of non-ionic surfactant vesicles: adjuvant-driven IgG2a production independent of MHC control
    Vaccine, vol. 12, no. 7, pp. 613–619, 1994
  45. Temporal differences in the expression of mRNA for IL-10 and IFN-γ in the brains and spleens of C57BL/10 mice infected with Toxoplasma gondii
    Parasite Immunology, vol. 16, no. 6, pp. 305–314, 1994
  46. Influence of genes within the MHC on mortality and brain cyst development in mice infected with Toxoplasma gondii: kinetics of immune regulation in BALB H-2 congenic mice
    Parasite Immunology, vol. 15, no. 6, pp. 317–324, 1993
  47. Cytokine control of Leishmania infection in the BALB/c mouse: enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent
    Parasite Immunology, vol. 14, no. 1, pp. 37–48, 1992
  48. Detection of cytokine mRNA in the brains of mice with toxoplasmic encephalitis
    Parasite Immunology, vol. 14, no. 4, pp. 405–413, 1992
  49. Demonstration of Leishmania specific cell mediated and humoral immunity in asymptomatic dogs
    Parasite Immunology, vol. 14, no. 5, pp. 531–539, 1992
  50. Kinetics of cytokine mRNA production in the brains of mice with progressive toxoplasmic encephalitis
    European Journal of Immunology, vol. 22, no. 9, pp. 2317–2322, 1992
  51. The induction of protective immunity toLeishmania major in the BALB/c mouse by interleukin 4 treatment
    European Journal of Immunology, vol. 19, no. 4, pp. 779–782, 1989
  52. A direct comparison of sodium stibogluconate treatment in two animal models of human visceral leishmaniasis, mouse and hamster
    International Journal of Pharmaceutics, vol. 53, no. 2, pp. 129–137, 1989
  53. Visceral leishmaniasis: Resistance to reinfection in the liver following chemotherapy in the BALB/c mouse
    Experimental Parasitology, vol. 68, no. 4, pp. 375–381, 1989