Patrick J. Bednarski

Articles in Scholarly Journals [Incomplete List]

  1. Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides
    Bioorganic & Medicinal Chemistry, vol. 15, no. 7, pp. 2560–2572, 2007
  2. Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data
    Anti-Cancer Drugs, vol. 18, no. 4, pp. 389–404, 2007
  3. Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data
    Anti-Cancer Drugs, vol. 17, no. 1, pp. 41–51, 2006
  4. Synthesis, reactions and structure–activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: Illudin analogs with in vitro cytotoxic activity
    Bioorganic & Medicinal Chemistry, vol. 14, no. 14, pp. 4694–4703, 2006
  5. 2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: Synthesis, in vitro cytotoxic activity, and QSAR investigations
    Bioorganic & Medicinal Chemistry, vol. 14, no. 21, pp. 7282–7292, 2006
  6. Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides
    Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 14, pp. 3663–3667, 2006
  7. Light-Activated Destruction of Cancer Cell Nuclei by Platinum Diazide Complexes
    Chemistry & Biology, vol. 13, no. 1, pp. 61–67, 2006
  8. Synthesis, structure and anticancer activity of novel 2,4-diamino-1,3,5-triazine derivatives
    European Journal of Medicinal Chemistry, vol. 41, no. 2, pp. 219–225, 2006
  9. Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines
    European Journal of Medicinal Chemistry, vol. 41, no. 5, pp. 633–639, 2006
  10. Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands
    Journal of Inorganic Biochemistry, vol. 100, no. 8, pp. 1389–1398, 2006
  11. No Correlation between GSH Levels in Human Cancer Cell Lines and the Cell Growth Inhibitory Activities of Platinum Diamine Complexes
    Archiv der Pharmazie, vol. 337, no. 12, pp. 668–671, 2004
  12. Journal of Medicinal Chemistry, vol. 47, no. 13, pp. 3438–3449, 2004
  13. Quantification of Elastase-Like Activity in 13 Human Cancer Cell Lines and in an Immortalized Human Epithelial Cell Line by RP-HPLC
    Biological Chemistry, vol. 384, no. 5, pp. 817–824, 2003
  14. Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines
    Analytical Biochemistry, vol. 320, no. 2, pp. 170–178, 2003
  15. Unusual reactivity of cytotoxic cis-dihydrazide Pt(II) complexes in aqueous solution
    Journal of Inorganic Biochemistry, vol. 96, no. 4, pp. 469–477, 2003
  16. Nucleotide Platination Induced by Visible Light
    Angewandte Chemie International Edition, vol. 38, no. 10, pp. 1460–1463, 1999
  17. Relationships between Reduction Properties and Cancer Cell Growth Inhibitory Activities ofcis-Dichloro- andcis-Diiodo-Pt(IV)-ethylenediamines
    Archiv der Pharmazie, vol. 332, no. 8, pp. 279–285, 1999
  18. Effect of thiols exported by cancer cells on the stability and growth-inhibitory activity of Pt(IV) complexes
    Journal of Cancer Research and Clinical Oncology, vol. 125, no. 12, pp. 690–696, 1999
  19. Journal of the American Chemical Society, vol. 120, no. 32, pp. 8253–8254, 1998
  20. Journal of Natural Products, vol. 60, no. 6, pp. 587–591, 1997
  21. Synthesis and X-ray Crystal Structure of trans,cis-[Pt(OAc)2I2(en)]: A Novel Type of Cisplatin Analog That Can Be Photolyzed by Visible Light to DNA-Binding and Cytotoxic Species in Vitro
    Journal of Medicinal Chemistry, vol. 39, no. 13, pp. 2499–2507, 1996
  22. Unusual reactivity of cisplatin analogs that bear o-phenylenediamine ligands: Insights for the design of more effective cytotoxic agents
    Journal of Inorganic Biochemistry, vol. 62, no. 4, pp. 281–298, 1996
  23. Chemical stability, biological activity and cellular uptake of a cisplatin analogue having a 1,2-diarylethyleneamine ligand in cultures of human breast cancer cells
    Journal of Cancer Research and Clinical Oncology, vol. 121, no. S1, pp. 31–38, 1995
  24. Reactions of a cisplatin analog bearing an estrogenic 1,2-diarylethylenediamine ligand with sulfur-containing amino acids and glutathione
    Journal of Inorganic Biochemistry, vol. 60, no. 1, pp. 1–19, 1995
  25. A Novel approach to preparing water soluble prodrug forms of cisplatin analogues bearing chelating diamines
    Journal of Pharmaceutical Sciences, vol. 84, no. 7, pp. 819–823, 1995
  26. Use of reversed-phase h.p.l.c. for determination of the hydrolysis rate constants of dichloro(1,2-diarylethylenediamine)platinum(II) complexes
    Transition Metal Chemistry, vol. 19, no. 5, pp. 513–517, 1994
  27. Synthesis and Evaluation of Sulfur-Containing Glutethimide Derivatives for Aromatase and Desmolase Inhibitory Activity
    Archiv der Pharmazie, vol. 326, no. 7, pp. 391–394, 1993
  28. High incidence of aneurysm formation following patch plasty repair of coarctation
    European Journal of Cardio-Thoracic Surgery, vol. 7, no. 4, pp. 200–205, 1993
  29. Journal of Medicinal Chemistry, vol. 35, no. 23, pp. 4479–4485, 1992
  30. Relationships between the aqueous chemistry and the in vitro cytotoxic activities of mixed-amine cisplatin analogues
    Biochemical Pharmacology, vol. 43, no. 12, pp. 2609–2620, 1992
  31. Inorganic Chemistry, vol. 30, no. 15, pp. 3015–3025, 1991
  32. Platinum compounds with estrogen receptor affinity
    Cancer Treatment Reviews, vol. 17, no. 2-3, pp. 221–231, 1990
  33. Journal of Medicinal Chemistry, vol. 32, no. 1, pp. 203–213, 1989
  34. Dissociation of 19-hydroxy-, 19-oxo-, and aromatizing-activities in human placental microsomes through the use of suicide substrates to aromatase
    Journal of Steroid Biochemistry, vol. 32, no. 2, pp. 309–316, 1989
  35. Journal of Medicinal Chemistry, vol. 28, no. 6, pp. 775–779, 1985
  36. Journal of Organic Chemistry, vol. 50, no. 15, pp. 2798–2799, 1985
  37. Journal of Medicinal Chemistry, vol. 27, no. 7, pp. 857–861, 1984