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Patrick J. Bednarski
Articles in Scholarly Journals [Incomplete List]
Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides
Bioorganic & Medicinal Chemistry, vol. 15, no. 7, pp. 2560–2572, 2007
Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data
Anti-Cancer Drugs, vol. 18, no. 4, pp. 389–404, 2007
Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data
Anti-Cancer Drugs, vol. 17, no. 1, pp. 41–51, 2006
Synthesis, reactions and structure–activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: Illudin analogs with in vitro cytotoxic activity
Bioorganic & Medicinal Chemistry, vol. 14, no. 14, pp. 4694–4703, 2006
2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: Synthesis, in vitro cytotoxic activity, and QSAR investigations
Bioorganic & Medicinal Chemistry, vol. 14, no. 21, pp. 7282–7292, 2006
Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides
Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 14, pp. 3663–3667, 2006
Light-Activated Destruction of Cancer Cell Nuclei by Platinum Diazide Complexes
Chemistry & Biology, vol. 13, no. 1, pp. 61–67, 2006
Synthesis, structure and anticancer activity of novel 2,4-diamino-1,3,5-triazine derivatives
European Journal of Medicinal Chemistry, vol. 41, no. 2, pp. 219–225, 2006
Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines
European Journal of Medicinal Chemistry, vol. 41, no. 5, pp. 633–639, 2006
Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands
Journal of Inorganic Biochemistry, vol. 100, no. 8, pp. 1389–1398, 2006
No Correlation between GSH Levels in Human Cancer Cell Lines and the Cell Growth Inhibitory Activities of Platinum Diamine Complexes
Archiv der Pharmazie, vol. 337, no. 12, pp. 668–671, 2004
Journal of Medicinal Chemistry, vol. 47, no. 13, pp. 3438–3449, 2004
Quantification of Elastase-Like Activity in 13 Human Cancer Cell Lines and in an Immortalized Human Epithelial Cell Line by RP-HPLC
Biological Chemistry, vol. 384, no. 5, pp. 817–824, 2003
Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines
Analytical Biochemistry, vol. 320, no. 2, pp. 170–178, 2003
Unusual reactivity of cytotoxic cis-dihydrazide Pt(II) complexes in aqueous solution
Journal of Inorganic Biochemistry, vol. 96, no. 4, pp. 469–477, 2003
Nucleotide Platination Induced by Visible Light
Angewandte Chemie International Edition, vol. 38, no. 10, pp. 1460–1463, 1999
Relationships between Reduction Properties and Cancer Cell Growth Inhibitory Activities ofcis-Dichloro- andcis-Diiodo-Pt(IV)-ethylenediamines
Archiv der Pharmazie, vol. 332, no. 8, pp. 279–285, 1999
Effect of thiols exported by cancer cells on the stability and growth-inhibitory activity of Pt(IV) complexes
Journal of Cancer Research and Clinical Oncology, vol. 125, no. 12, pp. 690–696, 1999
Journal of the American Chemical Society, vol. 120, no. 32, pp. 8253–8254, 1998
Journal of Natural Products, vol. 60, no. 6, pp. 587–591, 1997
Synthesis and X-ray Crystal Structure of trans,cis-[Pt(OAc)2I2(en)]: A Novel Type of Cisplatin Analog That Can Be Photolyzed by Visible Light to DNA-Binding and Cytotoxic Species in Vitro
Journal of Medicinal Chemistry, vol. 39, no. 13, pp. 2499–2507, 1996
Unusual reactivity of cisplatin analogs that bear o-phenylenediamine ligands: Insights for the design of more effective cytotoxic agents
Journal of Inorganic Biochemistry, vol. 62, no. 4, pp. 281–298, 1996
Chemical stability, biological activity and cellular uptake of a cisplatin analogue having a 1,2-diarylethyleneamine ligand in cultures of human breast cancer cells
Journal of Cancer Research and Clinical Oncology, vol. 121, no. S1, pp. 31–38, 1995
Reactions of a cisplatin analog bearing an estrogenic 1,2-diarylethylenediamine ligand with sulfur-containing amino acids and glutathione
Journal of Inorganic Biochemistry, vol. 60, no. 1, pp. 1–19, 1995
A Novel approach to preparing water soluble prodrug forms of cisplatin analogues bearing chelating diamines
Journal of Pharmaceutical Sciences, vol. 84, no. 7, pp. 819–823, 1995
Use of reversed-phase h.p.l.c. for determination of the hydrolysis rate constants of dichloro(1,2-diarylethylenediamine)platinum(II) complexes
Transition Metal Chemistry, vol. 19, no. 5, pp. 513–517, 1994
Synthesis and Evaluation of Sulfur-Containing Glutethimide Derivatives for Aromatase and Desmolase Inhibitory Activity
Archiv der Pharmazie, vol. 326, no. 7, pp. 391–394, 1993
High incidence of aneurysm formation following patch plasty repair of coarctation
European Journal of Cardio-Thoracic Surgery, vol. 7, no. 4, pp. 200–205, 1993
Journal of Medicinal Chemistry, vol. 35, no. 23, pp. 4479–4485, 1992
Relationships between the aqueous chemistry and the in vitro cytotoxic activities of mixed-amine cisplatin analogues
Biochemical Pharmacology, vol. 43, no. 12, pp. 2609–2620, 1992
Inorganic Chemistry, vol. 30, no. 15, pp. 3015–3025, 1991
Platinum compounds with estrogen receptor affinity
Cancer Treatment Reviews, vol. 17, no. 2-3, pp. 221–231, 1990
Journal of Medicinal Chemistry, vol. 32, no. 1, pp. 203–213, 1989
Dissociation of 19-hydroxy-, 19-oxo-, and aromatizing-activities in human placental microsomes through the use of suicide substrates to aromatase
Journal of Steroid Biochemistry, vol. 32, no. 2, pp. 309–316, 1989
Journal of Medicinal Chemistry, vol. 28, no. 6, pp. 775–779, 1985
Journal of Organic Chemistry, vol. 50, no. 15, pp. 2798–2799, 1985
Journal of Medicinal Chemistry, vol. 27, no. 7, pp. 857–861, 1984