Luigina Romani received her Ph.D. and M.D. degrees from the University of Perugia, Italy, where she was also trained in tumour immunology and transplant immunology. She carried out her postdoctoral training at the National Institute of Health, Bethesda, Md, USA, and she is currently a Professor of Pathology and a Faculty Member of the University of Perugia School of Medicine. She pioneered studies on the role of T cells first (early 80’s) and then of the different T-cell subsets (early 90’s) in experimental fungal infections. She introduced several novel scientific and translatable concepts which have become popular in the field of medical mycology. Examples are the concept of protective tolerance, the basis of immunotherapy, the use of dendritic cells to develop fungal vaccine, the pathogenetic role of inflammation in infection, the discovery of tryptophan metabolites as potential antifungal strategies, and, more recently, the use of functional genomic to predict individual risk for fungal infections in transplanted patients. She has been recognized as a Fellow of the American Academy of Microbiology and elected to the American National Academy of Sciences.
Biography Updated on 17 September 2012