Personal Home Page

http://www.kumc.edu/pharmacology/wan.html

Articles in Scholarly Journals [Incomplete List]

1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4 , and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
   Drug Metabolism and Disposition, vol. 35, no. 9, pp. 1700–1710, 2007
2. Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X Receptor Alpha
   PPAR Research, vol. 2006, Article ID 96341, 6 pages, 2006
3. Acetaminophen Metabolism Does Not Contribute to Gender Difference in Its Hepatotoxicity in Mouse
   Toxicological Sciences, vol. 92, no. 1, pp. 33–41, 2006
4. Retinoids Activate the RXR/SXR-Mediated Pathway and Induce the Endogenous CYP3A4 Activity in Huh7 Human Hepatoma Cells
   Toxicological Sciences, vol. 92, no. 1, pp. 51–60, 2006
5. Polymorphisms of Genes Encoding Phase I Enzymes in Mexican Americans - An Ethnic Comparison Study
   Current Pharmacogenomics, vol. 4, no. 4, pp. 345–353, 2006
6. The Role of Retinoid X Receptor   in Regulating Alcohol Metabolism
   Journal of Pharmacology and Experimental Therapeutics, vol. 319, no. 1, pp. 360–368, 2006
7. Comparison of Alcohol Drinking Behaviors and Associated Problems Between Benders and Nonbenders in Mexican Americans Who Drink Excessively
   Addictive Disorders & Their Treatment, vol. 5, no. 3, pp. 121–127, 2006
8. BMC Genetics, vol. 7, no. 1, p. 29, 2006
9. Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: A cross-ethnic comparative study
   Clinical Pharmacology & Therapeutics, vol. 80, no. 1, pp. 33–40, 2006
10. The effect of ethanol, ethanol metabolizing enzyme inhibitors, and Vitamin E on regulating glutathione, glutathione S-transferase, and S-adenosylmethionine in mouse primary hepatocyte
    Hepatology Research, vol. 35, no. 1, pp. 53–61, 2006
11. Identification of CYP2D6 impaired functional alleles in Mexican Americans
    European Journal of Clinical Pharmacology, vol. 61, no. 11, pp. 797–802, 2005
12. Evolution of the DRD2 gene haplotype and its association with alcoholism in Mexican Americans
    Alcohol, vol. 36, no. 2, pp. 117–125, 2005
13. 9-cis-Retinoic Acid Inhibits Androgen Receptor Activity through Activation of Retinoid X Receptor
    Molecular Endocrinology, vol. 19, no. 5, pp. 1200–1212, 2005
14. RXRalpha Regulates the Expression of Glutathione S-Transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver
    Molecular Pharmacology, 2005
15. Animal Models of Xenobiotic Receptors
    Current Drug Metabolism, vol. 6, no. 4, pp. 341–355, 2005
16. Characteristics and Drinking Patterns in Alcohol Abusing Mexican American Men
    Addictive Disorders & Their Treatment, vol. 3, no. 1, pp. 14–17, 2004
17. ADH1B*1, ADH1C*2, DRD2 (???141C Ins), and 5-HTTLPR Are Associated With Alcoholism in Mexican American Men Living in Los Angeles
    Alcoholism: Clinical & Experimental Research, vol. 28, no. 8, pp. 1145–1152, 2004
18. Retinoid X Receptor ? Regulates Glutathione Homeostasis and Xenobiotic Detoxification Processes in Mouse Liver
    Molecular Pharmacology, vol. 65, no. 3, pp. 550–557, 2004
19. Polymorphisms of CYP2C19 and CYP2D6 in Israeli Ethnic Groups
    American Journal of PharmacoGenomics, vol. 4, no. 6, pp. 395–401, 2004
20. Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABAA receptor ß3 subunit genes and alcoholism in Mexican-Americans
    Alcohol, vol. 32, no. 1, pp. 45–52, 2004
21. RXRa mRNA expression is associated with cell proliferation and cell cycle regulation in Hep3B cell
    Experimental and Molecular Pathology, vol. 76, no. 1, pp. 24–28, 2004
22. Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment
    Biological Psychiatry, vol. 54, no. 9, pp. 879–883, 2003
23. The ADH3*2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
    Experimental and Molecular Pathology, vol. 74, no. 2, pp. 183–189, 2003
24. RXRa-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity
    Experimental and Molecular Pathology, vol. 75, no. 3, pp. 194–200, 2003
25. Cytochrome P450 Genes Are Differentially Expressed in Female and Male Hepatocyte Retinoid X Receptor alpha-Deficient Mice
    Endocrinology, vol. 144, no. 6, pp. 2311–2318, 2003
26. Hepatocyte Retinoid X Receptor-alpha-Deficient Mice Have Reduced Food Intake, Increased Body Weight, and Improved Glucose Tolerance
    Endocrinology, vol. 144, no. 2, pp. 605–611, 2003
27. INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 (MRP3) IN VIVO IS INDEPENDENT OF CONSTITUTIVE ANDROSTANE RECEPTOR
    Drug Metabolism and Disposition, vol. 31, no. 11, pp. 1315–1319, 2003
28. INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND ALDH2 GENES IN A MEXICAN-AMERICAN POPULATION LIVING IN THE LOS ANGELES AREA
    Alcohol and Alcoholism, vol. 38, no. 1, pp. 93–94, 2003
29. The role of hepatocyte RXRa in xenobiotic-sensing nuclear receptor-mediated pathways
    European Journal of Pharmaceutical Sciences, vol. 15, no. 1, pp. 89–96, 2002
30. Regulation of peroxisome proliferator activated receptor a-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice
    Hepatology Research, vol. 19, no. 2, pp. 117–130, 2001
31. CYP2D6 polymorphism in a Mexican American population
    Clinical Pharmacology & Therapeutics, vol. 70, no. 6, pp. 552–560, 2001
32. Mallory Bodies Formed in Proteasome-Depleted Hepatocytes: An Immunohistochemical Study
    Experimental and Molecular Pathology, vol. 70, no. 1, pp. 7–18, 2001
33. Dexamethasone Enhances Mallory Body Formation in Drug-Primed Mouse Liver
    Experimental and Molecular Pathology, vol. 69, no. 3, pp. 202–210, 2000
34. Identification of Retinoic Acid-Responsive Elements on the HNF1a and HNF4a Genes
    Biochemical and Biophysical Research Communications, vol. 276, no. 3, pp. 837–842, 2000
35. Peroxisome proliferator activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptoralpha deficient mice
    Journal of Biological Chemistry, 2000
36. Fatty acyl-CoAs inhibit retinoic acid-induced apoptosis in Hep3B cells
    Cancer Letters, vol. 154, no. 1, pp. 19–27, 2000
37. Hepatocyte nuclear factor 1 mediates the cell density associated induction of the a-fetoprotein gene
    Hepatology Research, vol. 16, no. 3, pp. 195–210, 2000
38. Hepatocyte-Specific Mutation Establishes Retinoid X Receptor alpha as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver
    Molecular and Cellular Biology, vol. 20, no. 12, pp. 4436–4444, 2000
39. Mouse model of hepatocellular hyperplastic nodule formation characterization of mRNA expression
    Hepatology Research, vol. 15, no. 2, pp. 110–123, 1999
40. Role of CYP2E1 in the pathogenesis of alcoholic liver disease:modifications by cAMP and Ubiquitin-proteasome pathway (update October 1999)
    Frontiers in Bioscience, vol. 4, no. 1-3, p. a16, 1999
41. Pathogenesis of mallory body formation: studies using the drug-primed mouse model
    Hepatology Research, vol. 13, no. 1, pp. 42–54, 1998
42. Retinoic Acid Mediates Down-regulation of the alpha -Fetoprotein Gene through Decreased Expression of Hepatocyte Nuclear Factors
    Journal of Biological Chemistry, vol. 273, no. 45, pp. 30024–30032, 1998
43. Differentiation and antiproliferation effects of retinoic acid receptor ß in hepatoma cells
    Cancer Letters, vol. 124, no. 2, pp. 205–211, 1998
44. Retinoic Acid Differentially Regulates Retinoic Acid Receptor-Mediated Pathways in the HEP3B Cell Line
    Experimental Cell Research, vol. 238, no. 1, pp. 241–247, 1998
45. Mallory body formation by ethanol feeding in drug-primed mice
    Hepatology, vol. 27, no. 1, pp. 116–122, 1998
46. Inhibition of PPARa/RXRa-mediated direct hyperplasia pathways during griseofulvin-induced hepatocarcinogenesis
    Journal of Cellular Biochemistry, vol. 69, no. 2, pp. 189–200, 1998
47. A Transcript Map Encompassing the Multiple Endocrine Neoplasia Type-1 (MEN1) Locus on Chromosome 11q13
    Genomics, vol. 42, no. 3, pp. 405–412, 1997
48. Pancreatic endocrine tumors with loss of heterozygosity at the multiple endocrine neoplasia type I locus
    The American Journal of Surgery, vol. 173, no. 6, pp. 518–520, 1997
49. A 1.5-Megabase Physical Map Encompassing the Multiple Endocrine Neoplasia Type-1 (MEN1) Locus on Chromosome 11q13
    Genomics, vol. 38, no. 2, pp. 166–173, 1996
50. Different Response to Retinoic Acid of Two Teratocarcinoma Cell Lines
    Experimental Cell Research, vol. 219, no. 2, pp. 392–398, 1995
51. The Expression of Retinoid X Receptor Genes Is Regulated by All-trans-and 9-cis-Retinoic Acid in F9 Teratocarcinoma Cells
    Experimental Cell Research, vol. 210, no. 1, pp. 56–61, 1994
52. Putative tumor-suppressor gene on chromosome 11 is important in sporadic endocrine tumor formation,
    The American Journal of Surgery, vol. 167, no. 1, pp. 180–185, 1994
53. Expression of the peroxisome proliferator-activated receptor gene is decreased in experimental alcoholic liver disease
    Life Sciences, vol. 56, no. 5, pp. 307–317, 1994
54. Effects of toxic levels of lead on gene regulation in the male axis: increase in messenger ribonucleic acids and intracellular stores of gonadotrophs within the central nervous system [published erratum appears in Biol Reprod 1994 May;50(5):1203]
    Biology of Reproduction, vol. 50, no. 4, pp. 802–811, 1994
55. Enhanced ovarian inhibin subunit gene expression in aging rats is due to chronic anovulation
    Biology of Reproduction, vol. 49, no. 6, pp. 1208–1214, 1993
56. Inhibin subunit gene expression and distribution in the ovaries of immature, young adult, middle-aged, and old female rats
    Endocrinology, vol. 132, no. 1, pp. 319–326, 1993
57. Retinoic acid and its receptors
    The American Journal of Surgery, vol. 166, no. 1, pp. 50–53, 1993
58. Expression of estrogen receptor gene in mouse oocyte and during embryogenesis
    Molecular Reproduction and Development, vol. 33, no. 4, pp. 407–412, 1992
59. The effects of retinoic acid on the expression of a-fetoprotein and albumin genes in rat hepatoma cell lines
    Differentiation, vol. 50, no. 2, pp. 107–111, 1992
60. Retinoic acid regulates gene expression of retinoic acid receptors a,ß and ? in F9 mouse teratocarcinoma cells
    Differentiation, vol. 51, no. 3, pp. 219–224, 1992
61. Differential Expression of Retinoic Acid Receptor mRNA during Mouse Embryogenesis
    Development, Growth and Differentiation, vol. 34, no. 6, pp. 685–691, 1992
62. Expression of the ?-fetoprotein gene in adult rat liver
    Archives of Biochemistry and Biophysics, vol. 270, no. 1, pp. 267–276, 1989
63. Induction of major histocompatibility class I antigens by interferons in undifferentiated F9 cells
    Journal of Cellular Physiology, vol. 130, no. 2, pp. 276–283, 1987
64. Mouse Major Histocompatibility Class I Gene Expression Begins at Midsomite Stage and is Inducible in Earlier-Stage Embryos by Interferon
    Proceedings of the National Academy of Sciences, vol. 82, no. 8, pp. 2427–2431, 1985
65. Immunohistochemical Localization of Keratins in Skin and Internal Organs of Mouse Fetus During Development
    Annals of the New York Academy of Sciences, vol. 455, no. 1 Intermediate , pp. 724–725, 1985
66. Monoclonal antibodies to laminin reveal the heterogeneity of basement membranes in the developing and adult mouse tissues
    The Journal of Cell Biology, vol. 98, no. 3, pp. 971–979, 1984
67. Fluorescein-Conjugated Bandeiraea simplicifolia Lectin as a Marker of Endodermal, Yolk Sac, and Trophoblastic Differentiation in the Mouse Embryo
    Differentiation, vol. 24, no. 1-3, pp. 55–59, 1983
68. Immediate and delayed effects of vincristine administered during early postimplantation stages of murine embryogenesis
    Journal of Experimental Zoology, vol. 227, no. 1, pp. 49–55, 1983
69. Immunohistochemical localization of entactin and laminin in mouse embryos and fetuses*1
    Developmental Biology, vol. 100, no. 2, pp. 496–505, 1983
70. Distribution of Bandeiraea simplicifolia lectin binding sites in the genital organs of female and male mice
    Histochemistry, vol. 77, no. 2, pp. 233–241, 1983
71. Pregnancy-Related changes in the mouse oviduct and uterus revealed by differential binding of fluoresceinated lectins
    Histochemistry, vol. 79, no. 3, pp. 365–375, 1983
72. Mouse egg cylinders developed in vitro may form benign and malignant teratoid tumors
    Experientia, vol. 38, no. 1, pp. 128–129, 1982
73. Twinning and conjoined placentation in mice
    Journal of Experimental Zoology, vol. 221, no. 1, pp. 81–86, 1982
74. Development of early somitic mouse embryos in static culture in vitro
    Journal of Experimental Zoology, vol. 220, no. 2, pp. 219–225, 1982
75. Rat serum promotes the in vitro development of mouse blastocysts during early somitic stages of embryogenesis
    Journal of Experimental Zoology, vol. 217, no. 3, pp. 451–453, 1981