David J. Sweatt

Articles in Scholarly Journals [Incomplete List]

  1. An Atomic Switch for Memory
    Cell, vol. 129, no. 1, pp. 23–24, 2007
  2. Covalent Modification of DNA Regulates Memory Formation
    Neuron, vol. 53, no. 6, pp. 857–869, 2007
  3. Behavioural neuroscience: Down memory lane
    Nature, vol. 447, no. 7141, Article ID nature05716, 1 pages, 2007
  4. Developmental Regulation of Eed Complex Composition Governs a Switch in Global Histone Modification in Brain
    Journal of Biological Chemistry, vol. 282, no. 13, pp. 9962–9972, 2007
  5. Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior
    Human Molecular Genetics, vol. 15, no. 21, pp. 3241–3250, 2006
  6. ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning
    Learning & Memory, vol. 13, no. 3, pp. 322–328, 2006
  7. Amnesia or retrieval deficit? Implications of a molecular approach to the question of reconsolidation
    Learning & Memory, vol. 13, no. 5, pp. 498–505, 2006
  8. Evidence That DNA (Cytosine-5) Methyltransferase Regulates Synaptic Plasticity in the Hippocampus
    Journal of Biological Chemistry, vol. 281, no. 23, pp. 15763–15773, 2006
  9. Kinase Suppressor of Ras1 Compartmentalizes Hippocampal Signal Transduction and Subserves Synaptic Plasticity and Memory Formation
    Neuron, vol. 50, no. 5, pp. 765–779, 2006
  10. Memory
    Cellular and Molecular Life Sciences, vol. 63, no. 9, pp. 1009–1016, 2006
  11. Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome
    Journal of Neuroscience, vol. 26, no. 1, pp. 319–327, 2006
  12. Deletion of Kv4.2 Gene Eliminates Dendritic A-Type K+ Current and Enhances Induction of Long-Term Potentiation in Hippocampal CA1 Pyramidal Neurons
    Journal of Neuroscience, vol. 26, no. 47, pp. 12143–12151, 2006
  13.  1-Integrins Are Required for Hippocampal AMPA Receptor-Dependent Synaptic Transmission, Synaptic Plasticity, and Working Memory
    Journal of Neuroscience, vol. 26, no. 1, pp. 223–232, 2006
  14. Regulation of Nuclear Factor  B in the Hippocampus by Group I Metabotropic Glutamate Receptors
    Journal of Neuroscience, vol. 26, no. 18, pp. 4870–4879, 2006
  15. Functional Dissection of Reelin Signaling by Site-Directed Disruption of Disabled-1 Adaptor Binding to Apolipoprotein E Receptor 2: Distinct Roles in Development and Synaptic Plasticity
    Journal of Neuroscience, vol. 26, no. 7, pp. 2041–2052, 2006
  16. ERK/MAPK regulates the Kv4.2 potassium channel by direct phosphorylation of the pore-forming subunit
    AJP: Cell Physiology, vol. 290, no. 3, pp. C852–C861, 2005
  17. Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulated protein kinase
    Neuroscience, vol. 133, no. 4, pp. 969–981, 2005
  18. Modulation of Synaptic Plasticity and Memory by Reelin Involves Differential Splicing of the Lipoprotein Receptor Apoer2
    Neuron, vol. 47, no. 4, pp. 567–579, 2005
  19. Erratum: Craving cocaine pERKs up the amygdala
    Nature Neuroscience, vol. 8, no. 6, Article ID nn0605-835c, 1 pages, 2005
  20. Epigenetic mechanisms in memory formation
    Nature Reviews Neuroscience, vol. 6, no. 2, Article ID nrn1604, 10 pages, 2005
  21. Translating prions at the synapse
    Nature Cell Biology, vol. 6, no. 3, Article ID ncb0304-184b, 3 pages, 2004
  22. Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis
    Neuroscience, vol. 126, no. 2, pp. 305–312, 2004
  23. Neuronal MEK is important for normal fear conditioning in mice
    Journal of Neuroscience Research, vol. 75, no. 6, pp. 760–770, 2004
  24. Mitogen-activated protein kinases in synaptic plasticity and memory
    Current Opinion in Neurobiology, vol. 14, no. 3, pp. 311–317, 2004
  25. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
    Human Molecular Genetics, vol. 13, no. 21, pp. 2679–2689, 2004
  26. Regulation of Histone Acetylation during Memory Formation in the Hippocampus
    Journal of Biological Chemistry, vol. 279, no. 39, pp. 40545–40559, 2004
  27. Structure and Function of Kv4-Family Transient Potassium Channels
    Physiological Reviews, vol. 84, no. 3, pp. 803–833, 2004
  28. Calcium-Calmodulin-Dependent Kinase II Modulates Kv4.2 Channel Expression and Upregulates Neuronal A-Type Potassium Currents
    Journal of Neuroscience, vol. 24, no. 14, pp. 3643–3654, 2004
  29. MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time
    Journal of Neurochemistry, vol. 91, no. 2, pp. 349–361, 2004
  30. Protein Kinase C Overactivity Impairs Prefrontal Cortical Regulation of Working Memory
    Science, vol. 306, no. 5697, pp. 882–884, 2004
  31. Neuronal LRP1 Functionally Associates with Postsynaptic Proteins and Is Required for Normal Motor Function in Mice
    Molecular and Cellular Biology, vol. 24, no. 20, pp. 8872–8883, 2004
  32. Receptor Clustering Is Involved in Reelin Signaling
    Molecular and Cellular Biology, vol. 24, no. 3, pp. 1378–1386, 2004
  33. Generation and Characterization of LANP/pp32 Null Mice
    Molecular and Cellular Biology, vol. 24, no. 8, pp. 3140–3149, 2004
  34. Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1
    Molecular and Cellular Biology, vol. 24, no. 9, pp. 3782–3793, 2004
  35. A Bioinformatics Analysis of Memory Consolidation Reveals Involvement of the Transcription Factor c-Rel
    Journal of Neuroscience, vol. 24, no. 16, pp. 3933–3943, 2004
  36. Mouse Genetic Approaches to Investigating Calcium/Calmodulin-Dependent Protein Kinase II Function in Plasticity and Cognition
    Journal of Neuroscience, vol. 24, no. 39, pp. 8410–8415, 2004
  37. Reelin and Cyclin-Dependent Kinase 5-Dependent Signals Cooperate in Regulating Neuronal Migration and Synaptic Transmission
    Journal of Neuroscience, vol. 24, no. 8, pp. 1897–1906, 2004
  38. Genetics of Childhood Disorders: LI. Learning and Memory, Part 4: Human Cognitive Disorders and the ras/ERK/CREB Pathway
    Journal of the American Academy of Child & Adolescent Psychiatry, vol. 42, no. 6, pp. 741–744, 2003
  39. Genetics of Childhood Disorders: LII. Learning and Memory, Part 5: Human Cognitive Disorders and the ras/ERK/CREB Pathway
    Journal of the American Academy of Child & Adolescent Psychiatry, vol. 42, no. 7, pp. 873–876, 2003
  40. A Role for ERK MAP Kinase in Physiologic Temporal Integration in Hippocampal Area CA1
    Learning & Memory, vol. 10, no. 1, pp. 26–39, 2003
  41. Postsynaptic contributions to hippocampal network hyperexcitability induced by chronic activity blockade in vivo
    European Journal of Neuroscience, vol. 18, no. 7, pp. 1861–1872, 2003
  42. Mitochondrial Regulation of Synaptic Plasticity in the Hippocampus
    Journal of Biological Chemistry, vol. 278, no. 20, pp. 17727–17734, 2003
  43. A Fundamental Role for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels
    Journal of Biological Chemistry, vol. 278, no. 38, pp. 36445–36454, 2003
  44. Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory
    Molecular and Cellular Neuroscience, vol. 23, no. 1, pp. 1–12, 2003
  45. Pet-1 ETS Gene Plays a Critical Role in 5-HT Neuron Development and Is Required for Normal Anxiety-like and Aggressive Behavior
    Neuron, vol. 37, no. 2, pp. 233–247, 2003
  46. SCA7 Knockin Mice Model Human SCA7 and Reveal Gradual Accumulation of Mutant Ataxin-7 in Neurons and Abnormalities in Short-Term Plasticity
    Neuron, vol. 37, no. 3, pp. 383–401, 2003
  47. Rap1 Couples cAMP Signaling to a Distinct Pool of p42/44MAPK Regulating Excitability, Synaptic Plasticity, Learning, and Memory
    Neuron, vol. 39, no. 2, pp. 309–325, 2003
  48. Molecular Neurobiology of Human Cognition
    Neuron, vol. 33, no. 6, pp. 845–848, 2002
  49. A Long CAG Repeat in the Mouse Sca1 Locus Replicates SCA1 Features and Reveals the Impact of Protein Solubility on Selective Neurodegeneration
    Neuron, vol. 34, no. 6, pp. 905–919, 2002
  50. beta -Amyloid Peptide Activates alpha 7 Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes
    Journal of Biological Chemistry, vol. 277, no. 28, pp. 25056–25061, 2002
  51. Accelerated Plaque Accumulation, Associative Learning Deficits, and Up-regulation of alpha 7 Nicotinic Receptor Protein in Transgenic Mice Co-expressing Mutant Human Presenilin 1 and Amyloid Precursor Proteins
    Journal of Biological Chemistry, vol. 277, no. 25, pp. 22768–22780, 2002
  52. The Role of Mitochondrial Porins and the Permeability Transition Pore in Learning and Synaptic Plasticity
    Journal of Biological Chemistry, vol. 277, no. 21, pp. 18891–18897, 2002
  53. Glutamate Uptake in Synaptic Plasticity: From Mollusc to Mammal
    Current Molecular Medicine, vol. 2, no. 7, pp. 593–603, 2002
  54. MOLECULAR PSYCHOLOGY: Roles for the ERK MAP Kinase Cascade in Memory
    Annual Review of Pharmacology and Toxicology, vol. 42, no. 1, pp. 135–163, 2002
  55. Molecular Genetics of Human Cognition
    Molecular Interventions, vol. 2, no. 6, pp. 376–391, 2002
  56. ROLES OF SERINE/THREONINE PHOSPHATASES IN HIPPOCAMPAL SYNAPTIC PLASTICITY
    Nature Reviews Neuroscience, vol. 2, no. 7, Article ID 35081514, 13 pages, 2001
  57. Leitmotifs in the biochemistry of LTP induction: amplification, integration and coordination
    Journal of Neurochemistry, vol. 77, no. 4, pp. 961–971, 2001
  58. Mice Lacking the ERK1 Isoform of MAP Kinase Are Unimpaired in Emotional Learning
    Learning & Memory, vol. 8, no. 1, pp. 11–19, 2001
  59. Protein Kinase Inhibition by omega -3 Fatty Acids
    Journal of Biological Chemistry, vol. 276, no. 14, pp. 10888–10896, 2001
  60. Protooncogenes Subserve Memory Formation in the Adult CNS
    Neuron, vol. 31, no. 5, pp. 671–674, 2001
  61. Memory mechanisms: The yin and yang of protein phosphorylation
    Current Biology, vol. 11, no. 10, pp. R391–R394, 2001
  62. Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro
    Molecular Psychiatry, vol. 6, no. 2, pp. 246–248, 2001
  63. Input-Specific Immunolocalization of Differentially Phosphorylated Kv4.2 in the Mouse Brain
    Learning & Memory, vol. 7, no. 5, pp. 321–332, 2000
  64. The A-Type Potassium Channel Kv4.2 Is a Substrate for the Mitogen-Activated Protein Kinase ERK
    Journal of Neurochemistry, vol. 75, no. 6, pp. 2277–2287, 2000
  65. Kv4.2 Phosphorylation by Cyclic AMP-dependent Protein Kinase
    Journal of Biological Chemistry, vol. 275, no. 8, pp. 5337–5346, 2000
  66. Regulation of Myelin Basic Protein Phosphorylation by Mitogen-Activated Protein Kinase During Increased Action Potential Firing in the Hippocampus
    Journal of Neurochemistry, vol. 73, no. 3, pp. 1090–1097, 1999
  67. Toward a Molecular Explanation for Long-Term Potentiation
    Learning & Memory, vol. 6, no. 5, pp. 399–416, 1999
  68. A Necessity for MAP Kinase Activation in Mammalian Spatial Learning
    Learning & Memory, vol. 6, no. 5, pp. 478–490, 1999
  69. A Role for Superoxide in Protein Kinase C Activation and Induction of Long-term Potentiation
    Journal of Biological Chemistry, vol. 273, no. 8, pp. 4516–4522, 1998
  70. Nature Neuroscience, vol. 1, no. 7, pp. 602–609, 1998
  71. Mutation of the Angelman Ubiquitin Ligase in Mice Causes Increased Cytoplasmic p53 and Deficits of Contextual Learning and Long-Term Potentiation
    Neuron, vol. 21, no. 4, pp. 799–811, 1998
  72. Enhanced phosphorylation of the postsynaptic protein kinase C substrate RC3/neurogranin during long-term potentiation
    Brain Research, vol. 749, no. 2, pp. 181–187, 1997
  73. A Requirement for the Mitogen-activated Protein Kinase Cascade in Hippocampal Long Term Potentiation
    Journal of Biological Chemistry, vol. 272, no. 31, pp. 19103–19106, 1997
  74. A biochemist's view of long-term potentiation.
    Learning & Memory, vol. 3, no. 1, pp. 1–24, 1996
  75. Mechanism of Protein Kinase C Activation During the Induction and Maintenance of Long-Term Potentiation Probed Using a Selective Peptide Substrate
    Proceedings of the National Academy of Sciences, vol. 90, no. 18, pp. 8337–8341, 1993
  76. NMDA Receptor Activation Increases Cyclic AMP in Area CA1 of the Hippocampus via Calcium/Calmodulin Stimulation of Adenylyl Cyclase
    Journal of Neurochemistry, vol. 61, no. 5, pp. 1933–1942, 1993
  77. Amygdala Kindling Alters Protein Kinase C Activity in Dentate Gyrus
    Journal of Neurochemistry, vol. 59, no. 5, pp. 1761–1769, 1992
  78. Increased Phosphorylation of a 17-kDa Protein Kinase C Substrate (P17) in Long-Term Potentiation
    Journal of Neurochemistry, vol. 58, no. 4, pp. 1576–1579, 1992
  79. Long-Term sensitization training in Aplysia leads to an increase in calreticulin, a major presynaptic calcium-binding protein
    Neuron, vol. 9, no. 6, pp. 1013–1024, 1992
  80. Oxidation-induced persistent activation of protein kinase C in hippocampal homogenates*1
    Biochemical and Biophysical Research Communications, vol. 187, no. 3, pp. 1439–1445, 1992
  81. N-Methyl-D-Aspartate Receptor Activation Increases cAMP Levels and Voltage-Gated Ca2+ Channel Activity in Area CA1 of Hippocampus
    Proceedings of the National Academy of Sciences, vol. 88, no. 15, pp. 6467–6471, 1991
  82. Protein Synthesis During Acquisition of Long-Term Facilitation is Needed for the Persistent Loss of Regulatory Subunits of the Aplysia cAMP- Dependent Protein Kinase
    Proceedings of the National Academy of Sciences, vol. 87, no. 10, pp. 3788–3791, 1990
  83. 5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in aplysia sensory neurons
    Neuron, vol. 2, no. 6, pp. 1577–1586, 1989
  84. Development of a database of amino acid sequences for proteins identified and isolated on two-dimensional polyacrylamide gels
    Electrophoresis, vol. 10, no. 2, pp. 152–157, 1989
  85. Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation ofAplysia sensory neurons
    Nature, vol. 339, no. 6219, Article ID 339051a0, 3 pages, 1989
  86. FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
    Nature, vol. 342, no. 6247, Article ID 342275a0, 3 pages, 1989
  87. Sequencing proteins from acrylamide gels
    Nature, vol. 336, no. 6198, Article ID 336499a0, 1 pages, 1988
  88. Sequencing of Proteins from Two-Dimensional Gels by Using in situ Digestion and Transfer of Peptides to Polyvinylidene Difluoride Membranes: Application to Proteins Associated with Sensitization in Aplysia
    Proceedings of the National Academy of Sciences, vol. 85, no. 18, pp. 7008–7012, 1988
  89. Epidermal growth factor (EGF) stimulates inositol trisphosphate formation in cells which overexpress the EGF receptor
    Biochemical and Biophysical Research Communications, vol. 142, no. 3, pp. 688–695, 1987