Fred F. Kadlubar
Personal Home Page
http://www.acrc.uams.edu/directory/bio.asp?id=124
Articles in Scholarly Journals [Incomplete List]
- Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells
The Prostate, vol. 68, no. 4, pp. 408–417, 2008 - Reply to the letter to the Editor: “N-Acetyltransferases and the susceptibility to benzidine-induced bladder carcinogenesis”
International Journal of Cancer, vol. 121, no. 7, pp. 1637–1639, 2007 - A variant of the Cockayne syndrome B geneERCC6 confers risk of lung cancer
Human Mutation, vol. 29, no. 1, pp. 113–122, 2007 - Sulfotransferase 4A1
The International Journal of Biochemistry & Cell Biology, 2007 - The UGT2B17 gene deletion polymorphism and risk of prostate cancerA case–control study in Caucasians
Cancer Detection and Prevention, vol. 31, no. 4, pp. 310–315, 2007 - Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells?
Archives of Biochemistry and Biophysics, vol. 464, no. 2, pp. 169–175, 2007 - Processed meat intake, CYP2A6 activity and risk of colorectal adenoma
Carcinogenesis, vol. 28, no. 6, pp. 1210–1216, 2007 - DNA supercoiling suppresses real-time PCR: a new approach to the quantification of mitochondrial DNA damage and repair
Nucleic Acids Research, vol. 35, no. 4, pp. 1377–1388, 2007 - Cystine-Glutamate Transporter SLC7A11 Mediates Resistance to Geldanamycin but Not to 17-(Allylamino)-17-demethoxygeldanamycin
Molecular Pharmacology, vol. 72, no. 6, pp. 1637–1646, 2007 - Hormone-Metabolizing Genotypes: An Alternate Interpretation
Cancer Epidemiology Biomarkers & Prevention, vol. 16, no. 9, pp. 1911–1911, 2007 - Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
Pharmacogenetics and Genomics, vol. 16, no. 5, pp. 359–367, 2006 - Associations between Catalase Phenotype and Genotype: Modification by Epidemiologic Factors
Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 6, pp. 1217–1222, 2006 - Deletion Polymorphism of UDP-Glucuronosyltransferase 2B17 and Risk of Prostate Cancer in African American and Caucasian Men
Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 8, pp. 1473–1478, 2006 - Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition
Proceedings of the National Academy of Sciences, vol. 103, no. 24, pp. 9256–9261, 2006 - CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl
International Journal of Cancer, vol. 119, no. 11, pp. 2520–2526, 2006 - Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
Breast Cancer Research and Treatment, vol. 91, no. 3, pp. 249–258, 2005 - NAT2 slow acetylation and bladder cancer in workers exposed to benzidine
International Journal of Cancer, vol. 118, no. 1, pp. 161–168, 2005 - Expression of cytochromes P450 and glutathioneS-transferases in human prostate, and the potential for activation of heterocyclic amine carcinogensvia acetyl-coA-, PAPS- and ATP-dependent pathways
International Journal of Cancer, vol. 117, no. 1, pp. 8–13, 2005 - Identification of Functional Genetic Variants in and Their Association With Risk of Esophageal Cancer
Gastroenterology, vol. 129, no. 2, pp. 565–576, 2005 - Human Alpha Class Glutathione S‐Transferases: Genetic Polymorphism, Expression, and Susceptibility to Disease
Methods in Enzymology, vol. 401, pp. 9–42, 2005 - Chemical Research in Toxicology, vol. 18, no. 4, pp. 692–699, 2005
- Sex differences in cytochrome P450 1B1, an estrogen-metabolizing enzyme, in the rhesus monkey telencephalon
Journal of Chemical Neuroanatomy, vol. 29, no. 1, pp. 71–80, 2005 - Dietary Intake of Heterocyclic Amines and Benzo(a)Pyrene: Associations with Pancreatic Cancer
Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 9, pp. 2261–2265, 2005 - CYP3A43 Pro340Ala Polymorphism and Prostate Cancer Risk in African Americans and Caucasians
Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 5, pp. 1257–1261, 2005 - Common genetic polymorphisms in the 5???-flanking Region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity
Pharmacogenetics and Genomics, vol. 15, no. 7, pp. 465–473, 2005 - A Modified Host Cell Reactivation Assay to Measure DNA Repair Capacity for Removing 4-Aminobiphenyl Adducts: A Pilot Study of Bladder Cancer
Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 7, pp. 1832–1836, 2005 - Human glutathione S-transferase A2 polymorphisms
Pharmacogenetics, vol. 14, no. 1, pp. 35–44, 2004 - Mitochondrial Mutagenesis and Oxidative Stress in Human Prostate Cancer
Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis & Ecotoxicology Reviews, vol. 22, no. 1, pp. 1–12, 2004 - Association of SULT1A1 Phenotype and Genotype with Prostate Cancer Risk in African-Americans and Caucasians
Cancer Epidemiology Biomarkers & Prevention, vol. 13, no. 2, pp. 270–276, 2004 - Examination of Human Tissue Cytosols for Expression of Sulfotransferase Isoform 1A2 (SULT1A2) Using a SULT1A2-Specific Antibody
Molecular Pharmacology, vol. 67, no. 2, pp. 394–399, 2004 - Chemical Research in Toxicology, vol. 17, no. 12, pp. 1659–1666, 2004
- Chemical Research in Toxicology, vol. 17, no. 4, pp. 529–536, 2004
- Lack of association between Caucasian lung cancer risk and O6-methylguanine-DNA methyltransferase-codon 178 genetic polymorphism
Lung Cancer, vol. 44, no. 3, pp. 281–286, 2004 - Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepaticN-acetyltransferase and glutathioneS-transferase activities
Environmental and Molecular Mutagenesis, vol. 44, no. 4, pp. 265–276, 2004 - Increased transcriptional activity of theCYP3A4*1B promoter variant
Environmental and Molecular Mutagenesis, vol. 42, no. 4, pp. 299–305, 2003 - Association between a glutathioneS-transferase A1 promoter polymorphism and survival after breast cancer treatment
International Journal of Cancer, vol. 103, no. 6, pp. 810–814, 2003 - Variation in cyclooxygenase expression levels within the colorectum
Molecular Carcinogenesis, vol. 37, no. 1, pp. 25–31, 2003 - Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP–DNA adduct formation
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 523-524, pp. 193–200, 2003 - Chemical Research in Toxicology, vol. 16, no. 1, pp. 66–73, 2003
- Chemical Research in Toxicology, vol. 16, no. 9, pp. 1162–1173, 2003
- Chemical Research in Toxicology, vol. 16, no. 3, pp. 432–432, 2003
- Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis
Carcinogenesis, vol. 24, no. 9, pp. 1481–1487, 2003 - Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2
Carcinogenesis, vol. 24, no. 3, pp. 583–587, 2003 - Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke
Carcinogenesis, vol. 24, no. 4, pp. 719–725, 2003 - A new clue to glaucoma pathogenesis
The American Journal of Medicine, vol. 114, no. 8, pp. 697–698, 2003 - Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas
Pharmacogenetics, vol. 12, no. 2, pp. 145–150, 2002 - Basic or applied, it's the interaction that counts
Nature, vol. 417, no. 6885, Article ID 417117a, 1 pages, 2002 - Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
Lung Cancer, vol. 38, no. 1, pp. 15–21, 2002 - Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer
Toxicology, vol. 181-182, pp. 83–87, 2002 - Meat intake and cooking techniques: associations with pancreatic cancer
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 506-507, pp. 225–231, 2002 - Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F1 neonatal mouse
Cancer Letters, vol. 185, no. 1, pp. 13–19, 2002 - Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals
Archives of Biochemistry and Biophysics, vol. 403, no. 2, pp. 270–276, 2002 - Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 506-507, pp. 175–185, 2002 - Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells
Environmental and Molecular Mutagenesis, vol. 39, no. 2-3, pp. 134–142, 2002 - Carcinogen-DNA adducts in human breast epithelial cells
Environmental and Molecular Mutagenesis, vol. 39, no. 2-3, pp. 184–192, 2002 - Frequency ofCYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population
International Journal of Cancer, vol. 95, no. 2, pp. 96–101, 2001 - Concluding remarks: symposium on Genetic Susceptibility to Environmental Toxicants
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 482, no. 1-2, pp. 111–113, 2001 - Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 482, no. 1-2, pp. 57–69, 2001 - The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 482, no. 1-2, pp. 3–10, 2001 - Specific site methylation in the 5'-flanking region of CYP1A2 Interindividual differences in human livers
Life Sciences, vol. 69, no. 7, pp. 839–845, 2001 - In Vitro Human Tissue Models in Risk Assessment: Report of a Consensus-Building Workshop
Toxicological Sciences, vol. 59, no. 1, pp. 17–36, 2001 - Carcinogen substrate specificity of human COX-1 and COX-2
Carcinogenesis, vol. 22, no. 1, pp. 5–10, 2001 - Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression
Pharmacogenetics, vol. 11, no. 8, pp. 663–669, 2001 - METABOLIC ACTIVATION CAPACITY OF NEONATAL MICE IN RELATION TO THE NEONATAL MOUSE TUMORIGENICITY BIOASSAY1*
Drug Metabolism Reviews, vol. 32, no. 2, pp. 241–266, 2000 - Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline
Carcinogenesis, vol. 21, no. 6, pp. 1213–1219, 2000 - In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline
Carcinogenesis, vol. 21, no. 7, pp. 1347–1354, 2000 - Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls
Pharmacogenetics, vol. 10, no. 9, pp. 761–766, 2000 - Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol
Pharmacogenetics, vol. 10, no. 9, pp. 789–797, 2000 - Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide
Cancer Letters, vol. 156, no. 2, pp. 167–175, 2000 - Cancer Therapy and Polymorphisms of Cytochromes P450
Clinical Chemistry and Laboratory Medicine, vol. 38, no. 9, pp. 883–887, 2000 - Effect of Waterborne Potassium Permanganate Exposure on Manganese Content in Liver and Axial Muscle of Channel Catfish
Journal of Aquatic Animal Health, vol. 11, no. 3, p. 305, 1999 - Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method
Pharmacogenetics, vol. 9, no. 3, pp. 327–332, 1999 - Chemopreventive Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells In Vitro
Nutrition and Cancer, vol. 35, no. 1, pp. 80–86, 1999 - Chemical Research in Toxicology, vol. 12, no. 10, pp. 906–916, 1999
- Cell Biology and Toxicology, vol. 15, no. 6, pp. 389–394, 1999
- Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative
Cancer Letters, vol. 143, no. 2, pp. 167–171, 1999 - Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved
Carcinogenesis, vol. 20, no. 6, pp. 1107–1114, 1999 - Analyses of bronchial bulky DNA adduct levels and CYP2C9, GSTP1 and NQO1 genotypes in a Hungarian study population with pulmonary diseases
Carcinogenesis, vol. 20, no. 6, pp. 991–995, 1999 - CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice
Carcinogenesis, vol. 20, no. 9, pp. 1825–1830, 1999 - Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 424, no. 1-2, pp. 263–274, 1999 - The effects of phytoestrogens on human pancreatic tumor cells in vitro
Cancer Letters, vol. 142, no. 1, pp. 111–119, 1999 - An FDA Review of Sulfamethazine Toxicity
Regulatory Toxicology and Pharmacology, vol. 30, no. 3, pp. 217–222, 1999 - Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines
Chemico-Biological Interactions, vol. 109, no. 1-3, pp. 237–248, 1998 - Letter to the editor
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 405, no. 1, pp. 111–112, 1998 - Comparison of DNA adduct levels associated with oxidative stress in human pancreas
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 405, no. 2, pp. 125–133, 1998 - Bioactivation of the cooked food mutagen N-hydroxy-2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine by estrogen sulfotransferase in cultured human mammary epithelial cells
Carcinogenesis, vol. 19, no. 11, pp. 2049–2053, 1998 - Metabolic activation of methyl-hydroxylated derivatives of 7,12- dimethylbenz[a]anthracene by human liver dehydroepiandrosterone-steroid sulfotransferase
Carcinogenesis, vol. 19, no. 6, pp. 1071–1076, 1998 - Use of polyclonal antibodies against carcinogen–DNA adducts in analysis of carcinogenesis
Toxicology Letters, vol. 102-103, no. 1-2, pp. 441–446, 1998 - Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA
Carcinogenesis, vol. 18, no. 12, pp. 2403–2414, 1997 - Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes
Carcinogenesis, vol. 18, no. 4, pp. 851–854, 1997 - Metabolic activation of aromatic amines by human pancreas
Carcinogenesis, vol. 18, no. 5, pp. 1085–1092, 1997 - Effect of Waterborne Copper Sulfate Exposure on Copper Content in Liver and Axial Muscle of Channel Catfish
Journal of Aquatic Animal Health, vol. 9, no. 2, p. 144, 1997 - Chemoprotection against the formation of colon DNA adducts from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 376, no. 1-2, pp. 115–122, 1997 - Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 376, no. 1-2, pp. 135–142, 1997 - Neonatal Mouse Assay for Tumorigenicity: Alternative to the Chronic Rodent Bioassay,
Regulatory Toxicology and Pharmacology, vol. 26, no. 2, pp. 230–240, 1997 - Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer
Environmental Toxicology and Pharmacology, vol. 4, no. 3-4, pp. 277–281, 1997 - Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl–DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 378, no. 1-2, pp. 97–112, 1997 - Cell Proliferation in Rat Forestomach Following Oral Administration of Styrene Oxide
Fundamental and Applied Toxicology, vol. 30, no. 1, pp. 67–74, 1996 - SHORT COMMUNICATION: Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro
Carcinogenesis, vol. 17, no. 4, pp. 889–892, 1996 - Evidence of anti-benzo[a]pyrene diolepoxide-DNA adduct formation in human colon mucosa
Carcinogenesis, vol. 17, no. 9, pp. 2081–2083, 1996 - Inhibitory effect of caloric restriction on tumorigenicity induced by 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in the CD1 newborn mouse bioassay
Cancer Letters, vol. 104, no. 2, pp. 133–136, 1996 - Metabolic polymorphisms and carcinogen-DNA adduct formation in human populations
Pharmacogenetics, vol. 5, no. Special Issue, pp. S108–S117, 1995 - Genetic susceptibility and carcinogen-DNA adduct formation in human urinary bladder carcinogenesis
Toxicology Letters, vol. 82-83, pp. 627–632, 1995 - Formation of Malondialdehyde-Modified 2'-Deoxyguanosinyl Adduct from Metabolism of Chloral Hydrate by Mouse Liver Microsomes
Biochemical and Biophysical Research Communications, vol. 216, no. 3, pp. 1110–1117, 1995 - Quantitative Immunohistochemical Analysis of 4-Aminobiphenyl-DNA in Cultured Cells and Mice: Comparison to Gas Chromatography/Mass Spectroscopy Analysis
Chemical Research in Toxicology, vol. 8, no. 5, pp. 747–752, 1995 - Chemical Research in Toxicology, vol. 7, no. 6, pp. 733–739, 1994
- Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens
Nature, vol. 369, no. 6476, Article ID 369154a0, 2 pages, 1994 - Expression of monomorphic and polymorphic N-acetyltransferases in human colon
Biochemical Pharmacology, vol. 47, no. 5, pp. 914–917, 1994 - Hepatic Metabolism of Chloral Hydrate to Free Radical(s) and Induction of Lipid Peroxidation
Biochemical and Biophysical Research Communications, vol. 204, no. 2, pp. 937–943, 1994 - Study of sodium saccharin co-carcinogenicity in the rat
Food and Chemical Toxicology, vol. 32, no. 3, pp. 207–213, 1994 - Plasma proteins as early biomarkers of exposure to carcinogenic aromatic amines
Chemico-Biological Interactions, vol. 93, no. 3, pp. 221–234, 1994 - Biochemical Individuality and Its Implications for Drug and Carcinogen Metabolism: Recent Insights from Acetyltransferase and Cytochrome P4501a2 Phenotyping and Genotyping in Humans
Drug Metabolism Reviews, vol. 26, no. 1, pp. 37–46, 1994 - Role of acetylation in colorectal cancer
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 290, no. 1, pp. 35–42, 1993 - Metabolic activation, DNA adducts, and H-ras mutations in human neoplastic and non-neoplastic laryngeal tissue
Journal of Cellular Biochemistry, vol. 53, no. S17F, pp. 129–137, 1993 - Chemical Research in Toxicology, vol. 6, no. 4, pp. 480–485, 1993
- Inducibility of human cytochromes P-450 primarily involved in the activation of chemical carcinogens
Chemosphere, vol. 25, no. 1-2, pp. 201–204, 1992 - Chemical Research in Toxicology, vol. 5, no. 5, pp. 691–697, 1992
- Detection of human DNA–carcinogen adducts
Nature, vol. 360, no. 6400, Article ID 360189a0, 1 pages, 1992 - Chemical Research in Toxicology, vol. 5, no. 4, pp. 479–490, 1992
- N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells
Biochemical and Biophysical Research Communications, vol. 185, no. 3, pp. 839–844, 1992 - Mutagenicity of nitro-polycyclic aromatic hydrocarbons with the nitro substituent situated at the longest molecular axis
Mutation Research Letters, vol. 283, no. 1, pp. 45–52, 1992 - Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse
Cancer Letters, vol. 62, no. 3, pp. 205–209, 1992 - Advantages and limitations of laboratory methods for measurement of carcinogen-DNA adducts for epidemiological studies
Toxicology Letters, vol. 64-65, pp. 469–475, 1992 - Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites
Pharmacogenetics, vol. 2, no. 3, pp. 116–127, 1992