Yijun Chen received a B.S. degree in pharmaceutical sciences at China Pharmaceutical University, Nanjing, China, in 1982 and completed his Ph.D. degree in medicinal and natural products chemistry at the University of Iowa, Iowa, USA, in 1996 under the guidance of Professor John P.N. Rosazza. After his postdoctoral research with Professor Edward A. Dennis at the University of California, San Diego, USA, Dr. Chen involved in the study of metabolic engineering for ascorbate production from 1998 to 1999 at MicroGenomics, Inc., San Diego, USA. From 1999 to 2006, Dr. Chen served as a Senior Research Investigator at Lead Discovery and Enzyme Technology Departments of Bristol-Myers Squibb Pharmaceutical Research Institute in New Brunswick, NJ, USA. Since 2007, Dr. Chen has been appointed as an Endowed Professor and the Director of Laboratory of Chemical Biology at China Pharmaceutical University, and he presently serves also as an Adjunct Professor of the Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, USA. The research of Dr. Chen’s group focuses on elucidation of biosynthetic pathways for microbial secondary metabolites, discovery of novel antitumor targets using natural small molecules as probe and analysis of biological functions at molecular and cellular levels, development of unique biocatalytic routes for chiral drug intermediates, and discovery of novel enzymes and mechanistic study on their catalytic functions.
Biography Updated on 22 January 2013