Eiichi Kumamoto works as Professor and Chair in the Department of Physiology, Faculty of Medicine, Saga University (Saga Medical School, Saga, Japan). He graduated from the Department of Chemistry, Faculty of Science, Kyushu University (Fukuoka, Japan), in 1975 and obtained a Ph.D. degree from Kyushu University (Fukuoka, Japan) for his research on ion transport through artificial membrane in 1980. Since 1980, he Kumamoto has worked in Saga Medical School. At first, he examined the modulation of synaptic transmission in sympathetic ganglion neurons by using the sharp-glass microelectrode technique. Then, he examined the electrophysiological properties of amino-acid receptor channels expressed in cultured CNS neurons by using the whole-cell patch-clamp technique. In 1986–1988, Kumamoto conducted work on synaptic transmission in parasympathetic ganglion neurons in the laboratory of Professor Patricia Shinnick-Gallagher in the Department of Pharmacology, University of Texas, Galveston, Tex, USA. In recent years, his main efforts are devoted to elucidating cellular mechanisms for the modulation of synaptic transmission by endogenous and exogenous analgesics (particularly, neuropeptides and TRP channel agonists) in the spinal dorsal horn and also the inhibition of nerve conduction by various substances (particularly, plant-derived chemicals) with an interest in the regulation of nociceptive transmission to the CNS from periphery.
Biography Updated on 7 February 2013