Paulo Vale works as a Researcher at the former Portuguese Institute of Fisheries and Sea Research (IPIMAR), currently merged into IPMA. Started in 1991 as ungraduate plant biology student, and in 2000 obtained is PhD in Biology (both degrees from Lisbon University). Since 1991 has been engaged in cultivation of toxic marine microalgae and specialized in detection by LC of marine biotoxins in microalgae and bivalve mollusks. Detection techniques involve diode array, fluorescence and mass spectrometry coupling. Implemented in-house LC methodologies for several groups of toxins: dinophysistoxins, pectenotoxins, azaspiracids, domoic acid and saxitoxins. Has been involved in understanding some human poisoning outbreaks, involving additionally the tetrodotoxins and ciguatoxins. Other research areas include toxin transformation taking place in bivalves after microalgae feeding. Additional detection techniques studied include several commercial immunoassay formats (ELISA, lateral flow immuno-chromatography), and enzyme inhibition assays. Since 1994 has been involved with the national monitoring programme for bivalve safety, implementing HPLC techniques aimed at replacing live animal bioassays. In 2002 became the technical responsible for the national reference laboratory for marine biotoxins within the EU-RL network. Has participated as technical expert on missions for inspecting production of live bivalve mollusks organized by the Food and Veterinary Office (FVO) (DG-SANCO, European Commission) carried out in EU member states and in third countries.
Biography Updated on 4 September 2012