Dr. Arun Srivastava is George H. Kitzman Professor of Genetics and Chief of Division of Cellular & Molecular Therapy in the Departments of Pediatrics, and Molecular Genetics & Microbiology, and Powell Gene Therapy Center at the University of Florida (UF). For the past 30 years, Dr. Srivastava’s research has been focused on the following two parvoviruses, the non-pathogenic adeno-associated virus (AAV), and a common human pathogen, the parvovirus B19, and the development of recombinant parvovirus vectors in human gene therapy. His laboratory has made seminal contributions to the field of parvoviruses. and developed strategies to achieve therapeutic levels of proteins at reduced vector doses as well as to reduce the host immune responses to AAV vectors for the potential gene therapy of human diseases. The current emphasis is on developing recombinant vectors for gene therapy for genetic diseases such as ß-thalassemia and sickle cell disease, and malignant disorders such as hepatoblastoma and hepatocellular carcinoma. Dr. Srivastava's research activities are currently supported by grants from the National Institutes of Health and the Bayer Hemophilia Program. He has also been awarded 3 US Patents on his research on human parvoviruses and their potential use as vectors in human gene therapy. He currently serves on the NIH Study Section as well as on the Editorial Boards of Journal of Virology, Gene Therapy, Human Gene Therapy, Recent Patents on DNA and Gene Sequences, Gene Therapy and Molecular Biology, and Journal of Chinese Integrative Medicine. Dr. Srivastava has published more than 150 research articles, mostly on human parvoviruses, in peer-reviewed journals, reviews, and book chapters.
Biography Updated on 18 October 2011