Alvaro Puga

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http://www.eh.uc.edu/dir_individual_details.asp?qcontactid=82

Articles in Scholarly Journals [Incomplete List]

  1. Long term low-dose arsenic exposure induces loss of DNA methylation
    Biochemical and Biophysical Research Communications, vol. 352, no. 1, pp. 188–192, 2007
  2. HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1769, no. 9-10, pp. 569–578, 2007
  3. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
    Nucleic Acids Research, vol. 35, no. 21, pp. 7074–7086, 2007
  4. Ligand-Independent Regulation of Transforming Growth Factor  1 Expression and Cell Cycle Progression by the Aryl Hydrocarbon Receptor
    Molecular and Cellular Biology, vol. 27, no. 17, pp. 6127–6139, 2007
  5. Chromium Cross-Links Histone Deacetylase 1-DNA Methyltransferase 1 Complexes to Chromatin, Inhibiting Histone-Remodeling Marks Critical for Transcriptional Activation
    Molecular and Cellular Biology, vol. 27, no. 20, pp. 7089–7101, 2007
  6. Impact of Cyp1a2 or Ahr gene knockout in mice: Implications for biomonitoring studies
    Toxicology Letters, vol. 162, no. 2-3, pp. 246–249, 2006
  7. Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs
    Biochemical and Biophysical Research Communications, vol. 348, no. 1, pp. 120–123, 2006
  8. Ah receptor signals cross-talk with multiple developmental pathways
    Biochemical Pharmacology, vol. 69, no. 2, pp. 199–207, 2005
  9. Butylhydroquinone Protects Cells Genetically Deficient in Glutathione Biosynthesis from Arsenite-Induced Apoptosis Without Significantly Changing Their Prooxidant Status
    Toxicological Sciences, vol. 87, no. 2, pp. 365–384, 2005
  10. Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis
    Journal of Cellular Biochemistry, vol. 96, no. 6, pp. 1174–1184, 2005
  11. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase Iand synergistic induction of phase II genes
    Molecular Pharmacology, 2005
  12. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Blocks Androgen-Dependent Cell Proliferation of LNCaP Cells through Modulation of pRB Phosphorylation
    Molecular Pharmacology, vol. 66, no. 3, pp. 502–511, 2004
  13. A Critical Role For MAP Kinases in the Control of Ah Receptor Complex Activity
    Toxicological Sciences, vol. 82, no. 1, pp. 80–87, 2004
  14. Different Global Gene Expression Profiles in Benzo[a]Pyrene- and Dioxin-Treated Vascular Smooth Muscle Cells of AHR-Knockout and Wild-Type Mice
    Cardiovascular Toxicology, vol. 4, no. 1, pp. 47–74, 2004
  15. Gene Expression Profiles of Mouse Aorta and Cultured Vascular Smooth Muscle Cells Differ Widely, Yet Show Common Responses to Dioxin Exposure
    Cardiovascular Toxicology, vol. 4, no. 4, pp. 385–404, 2004
  16. Expression of genes in the TGF-ß signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice
    Toxicology and Applied Pharmacology, vol. 194, no. 1, pp. 79–89, 2004
  17. Retention of Cr(III) by high-performance chelation ion chromatography interfaced to inductively-coupled plasma mass spectrometric detection with collision cell
    Journal of Chromatography A, vol. 1024, no. 1-2, pp. 129–137, 2004
  18. The Aryl Hydrocarbon Receptor Displaces p300 from E2F-dependent Promoters and Represses S Phase-specific Gene Expression
    Journal of Biological Chemistry, vol. 279, no. 28, pp. 29013–29022, 2004
  19. Chromium Inhibits Transcription from Polycyclic Aromatic Hydrocarbon-inducible Promoters by Blocking the Release of Histone Deacetylase and Preventing the Binding of p300 to Chromatin
    Journal of Biological Chemistry, vol. 279, no. 6, pp. 4110–4119, 2003
  20. Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function
    Biochemical Pharmacology, vol. 64, no. 5-6, pp. 771–780, 2002
  21. Induction of cellular oxidative stress by aryl hydrocarbon receptor activation
    Chemico-Biological Interactions, vol. 141, no. 1-2, pp. 77–95, 2002
  22. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor
    Free Radical Biology and Medicine, vol. 33, no. 9, pp. 1268–1278, 2002
  23. Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 517, no. 1-2, pp. 101–111, 2002
  24. Role of the aryl hydrocarbon receptor in cell cycle regulation
    Toxicology, vol. 181-182, pp. 171–177, 2002
  25. Dioxin Exposure Is an Environmental Risk Factor for Ischemic Heart Disease
    Cardiovascular Toxicology, vol. 1, no. 4, pp. 285–298, 2001
  26. Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells
    Biochemical Pharmacology, vol. 61, no. 5, pp. 605–612, 2001
  27. The transcriptional signature of dioxin in human hepatoma HepG2 cells
    Biochemical Pharmacology, vol. 60, no. 8, pp. 1129–1142, 2000
  28. Activation of transcription factors activator protein-1 and nuclear factor-?B by 2,3,7,8-Tetrachlorodibenzo-p-dioxin
    Biochemical Pharmacology, vol. 59, no. 8, pp. 997–1005, 2000
  29. Disruption of dioxin-inducible phase I and phase II gene expression patterns by cadmium, chromium, and arsenic
    Molecular Carcinogenesis, vol. 28, no. 4, pp. 225–235, 2000
  30. Aromatic Hydrocarbon Receptor Interaction with the Retinoblastoma Protein Potentiates Repression of E2F-dependent Transcription and Cell Cycle Arrest
    Journal of Biological Chemistry, vol. 275, no. 4, pp. 2943–2950, 2000
  31. FUNCTIONAL GENOMICS OF PARTICLE-INDUCED LUNG INJURY
    Inhalation Toxicology, vol. 12, no. 9, pp. 59–73, 2000
  32. Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest
    Oncogene, vol. 19, no. 15, pp. 1857–1867, 2000
  33. REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN
    Annual Review of Pharmacology and Toxicology, vol. 39, no. 1, pp. 67–101, 1999
  34. Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones
    Chemico-Biological Interactions, vol. 123, no. 1, pp. 31–49, 1999
  35. Trout CYP1A3 Gene: Recognition of Fish DNA Motifs by Mouse Regulatory Proteins
    Marine Biotechnology, vol. 1, no. 2, pp. 155–166, 1999
  36. Dioxin Causes a Sustained Oxidative Stress Response in the Mouse
    Biochemical and Biophysical Research Communications, vol. 253, no. 1, pp. 44–48, 1998
  37. Sustained Increase in Intracellular Free Calcium and Activation of Cyclooxygenase-2 Expression in Mouse Hepatoma Cells Treated with Dioxin
    Biochemical Pharmacology, vol. 54, no. 12, pp. 1287–1296, 1997
  38. Human Ah receptor (AHR) gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility
    Pharmacogenetics, vol. 7, no. 2, pp. 95–100, 1997
  39. Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism
    Proceedings of the National Academy of Sciences, vol. 93, no. 4, pp. 1671–1676, 1996
  40. Differential Regulation of Mouse Ah Receptor Gene Expression in Cell Lines of Different Tissue Origins
    Archives of Biochemistry and Biophysics, vol. 333, no. 1, pp. 170–178, 1996
  41. Dioxin Induces Transcription ofandGenes byReceptor-Dependent and -Independent Pathways
    Toxicology and Applied Pharmacology, vol. 141, no. 1, pp. 238–247, 1996
  42. The Y-box Motif Mediates Redox-dependent Transcriptional Activation in Mouse Cells
    Journal of Biological Chemistry, vol. 270, no. 51, pp. 30499–30507, 1995
  43. Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT)
    Biochemical Pharmacology, vol. 48, no. 9, pp. 1767–1778, 1994
  44. Localization of the murine Hmg1 gene, encoding an HMG-box protein, to mouse Chromosome 2
    Mammalian Genome, vol. 4, no. 10, pp. 612–614, 1993
  45. The 5' untranslated region of the human ?-glutamyl transferase mRNA contains a tissue-specific active translational enhancer
    FEBS Letters, vol. 332, no. 1-2, pp. 88–92, 1993
  46. Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice
    Pharmacogenetics, vol. 3, no. 6, pp. 312–321, 1993
  47. Role of the Ah Receptor and the Dioxin-Inducible [Ah] Gene Battery in Toxicity, Cancer, and Signal Transduction
    Annals of the New York Academy of Sciences, vol. 685, no. 1 Immunomodulat, pp. 624–640, 1993
  48. Negative regulation of the murine cytosolic aldehyde dehydrogenase-3 (Aldh-3c) gene by functional CYP1A1 and CYP1A2 proteins
    Biochemical and Biophysical Research Communications, vol. 187, no. 1, pp. 413–419, 1992
  49. Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin
    Pharmacogenetics, vol. 1, no. 2, pp. 68–78, 1991
  50. Expression of a viral gene in insulin-producing cell lines renders them susceptible to immunological destruction
    Diabetologia, vol. 32, no. 10, pp. 709–715, 1989
  51. Homology between murine and human cellular DNA sequences and the terminal repetition of the S component of herpes simplex virus type 1 DNA
    Cell, vol. 31, no. 1, pp. 81–87, 1982
  52. Herpes simplex virus DNA and mRNA sequences in acutely and chronically infected trigeminal ganglia of mice
    Virology, vol. 89, no. 1, pp. 102–111, 1978