Menico Rizzi received an M.S. degree in chemistry from the University of Pavia, Italy, and a Ph.D. degree in biotechnology from the University Cattolica del Sacro Cuore, Piacenza, Italy. We was a recipient of an EMBO Fellowship at EMBL/DESY outstation, Hamburg, Germany, and a Visiting Scientist at the Department of Chemistry, University of York, North Yorkshire, UK. Presently, he is a Professor of biochemistry at the School of Pharmacy, University of Piemonte Orientale Novara, Italy, where he is also responsible of the Ph.D. program in pharmaceutical biotechnology. He is the Coordinator of the Protein Structure and Function Group of the Italian Society of Biochemistry and Molecular Biology. Professor Rizzi is the Head of a group studying the biochemistry and structural biology of enzymes of medical interest with emphasis on diseases linked to poverty. The group is currently studying Mycobacterium tuberculosis enzymes involved in NAD(P) homeostasis, central metabolism, arabinogalactan synthesis, DNA repair, and host-bacterium interaction. The major goal of the research activity is the description of the catalytic mechanism adopted by the selected enzymes using as a core activity X-ray crystallography, flanked by kinetics analysis and site-directed mutagenesis.
Biography Updated on 30 July 2012