Silvio Aime

Articles in Scholarly Journals [Incomplete List]

  1. From Spherical to Osmotically Shrunken Paramagnetic Liposomes: An Improved Generation of LIPOCEST MRI Agents with Highly Shifted Water Protons
    Angewandte Chemie International Edition, vol. 46, no. 6, pp. 966–968, 2007
  2. Peptide Derivatized Lamellar Aggregates as Target-Specific MRI Contrast Agents
    ChemBioChem, vol. 8, no. 8, pp. 950–955, 2007
  3. Relaxometric and Modelling Studies of the Binding of a Lipophilic Gd-AAZTA Complex to Fatted and Defatted Human Serum Albumin
    Chemistry - A European Journal, vol. 13, no. 20, pp. 5785–5797, 2007
  4. The effects of intramolecular H-bond formation on the stability constant and water exchange rate of the Gd(III)-diethylenetriamine-Nâ?²-(3-amino-1,1-propylenephosphonic)-N,N,Nâ?³,Nâ?³-tetraacetate complex
    Contrast Media & Molecular Imaging, vol. 2, no. 2, pp. 94–102, 2007
  5. Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation
    NMR in Biomedicine, vol. 20, no. 1, pp. 40–48, 2007
  6. Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display
    Journal of Molecular Medicine, vol. 85, no. 8, pp. 897–906, 2007
  7. An iron-based T 1 contrast agent made of iron-phosphate complexes: In vitro and in vivo studies
    Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 20, no. 1, pp. 27–37, 2007
  8. New CD derivatives as self-assembling contrast agents for magnetic resonance imaging (MRI)
    Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 57, no. 1-4, pp. 489–495, 2007
  9. Optimized Relaxivity and Stability of [Gd(H(2,2)-1,2-HOPO)(H2O)]- for Use as an MRI Contrast Agent1
    Inorganic Chemistry, vol. 46, no. 12, pp. 4796–4798, 2007
  10. Gd-Loaded Liposomes as T1, Susceptibility, and CEST Agents, All in One
    Journal of the American Chemical Society, vol. 129, no. 9, pp. 2430–2431, 2007
  11. Highly Soluble Tris-hydroxypyridonate Gd(III) Complexes with Increased Hydration Number, Fast Water Exchange, Slow Electronic Relaxation, and High Relaxivity1
    Journal of the American Chemical Society, vol. 129, no. 7, pp. 1870–1871, 2007
  12. Journal of the American Chemical Society, vol. 128, no. 16, pp. 5344–5345, 2006
  13. Journal of the American Chemical Society, vol. 128, no. 29, pp. 9272–9273, 2006
  14. Journal of the American Chemical Society, vol. 128, no. 35, pp. 11326–11327, 2006
  15. Journal of Medicinal Chemistry, vol. 49, no. 16, pp. 4926–4936, 2006
  16. Improved syntheses of bis(β-cyclodextrin) derivatives, new carriers for gadolinium complexes
    Organic & Biomolecular Chemistry, vol. 4, no. 6, p. 1124, 2006
  17. Glycoconjugates of gadolinium complexes for MRI applications
    Chemical Communications, no. 10, p. 1064, 2006
  18. Relaxometric and solution NMR structural studies on ditopic lanthanide(iii) complexes of a phosphinate analogue of DOTA with a fast rate of water exchange
    Dalton Transactions, no. 19, p. 2323, 2006
  19. On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes
    Dalton Transactions, no. 47, p. 5605, 2006
  20. Magnetic Resonance Visualization of Tumor Angiogenesis by Targeting Neural Cell Adhesion Molecules with the Highly Sensitive Gadolinium-Loaded Apoferritin Probe
    Cancer Research, vol. 66, no. 18, pp. 9196–9201, 2006
  21. Inorganic Chemistry, vol. 45, no. 20, pp. 8355–8364, 2006
  22. The crystallized solvent could influence the lanthanide water bonding?
    Inorganica Chimica Acta, vol. 359, no. 10, pp. 3405–3411, 2006
  23. New paramagnetic supramolecular adducts for MRI applications based on non-covalent interactions between Gd(III)-complexes and ß- or ?-cyclodextrin units anchored to chitosan
    Journal of Inorganic Biochemistry, vol. 100, no. 5-6, pp. 931–938, 2006
  24. Polarization transfer from para-hydrogen to heteronuclei: Effect of H/D substitution. The case of AA'X and A2A2'X spin systems
    Journal of Magnetic Resonance, vol. 178, no. 2, pp. 184–192, 2006
  25. A responsive MRI contrast agent to monitor functional cell status
    NeuroImage, vol. 32, no. 3, pp. 1142–1149, 2006
  26. Neural-cell adhesion molecule (NCAM) expression by immature and tumor-derived endothelial cells favors cell organization into capillary-like structures
    Experimental Cell Research, vol. 312, no. 6, pp. 913–924, 2006
  27. Bioconjugate Chemistry, vol. 17, no. 4, pp. 975–987, 2006
  28. Magnetic resonance imaging of tumor cells by targeting the amino acid transport system
    Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 15, pp. 4111–4114, 2006
  29. High sensitivity lanthanide(III) based probes for MR-medical imaging
    Coordination Chemistry Reviews, vol. 250, no. 11-12, pp. 1562–1579, 2006
  30. High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI
    JBIC Journal of Biological Inorganic Chemistry, vol. 12, no. 2, pp. 267–276, 2006
  31. Effect of the intracellular localization of a Gd-based imaging probe on the relaxation enhancement of water protons
    Magnetic Resonance in Medicine, vol. 55, no. 3, pp. 491–497, 2006
  32. Quantification of the expression level of integrin receptor avß3 in cell lines and MR imaging with antibody-coated iron oxide particles
    Magnetic Resonance in Medicine, vol. 56, no. 4, pp. 711–716, 2006
  33. Water exchange across the erythrocyte plasma membrane studied by HR-MAS NMR spectroscopy
    Magnetic Resonance in Medicine, vol. 56, no. 5, pp. 978–985, 2006
  34. Para-hydrogen enrichment and hyperpolarization
    Concepts in Magnetic Resonance Part A, vol. 28A, no. 5, pp. 321–330, 2006
  35. New Insights for Pursuing High Relaxivity MRI Agents from Modelling the Binding Interaction of GdIII Chelates to HSA
    ChemBioChem, vol. 6, no. 5, pp. 818–820, 2005
  36. Gadolinium(III) Complexes of dota-DerivedN-Sulfonylacetamides (H4(dota-NHSO2R)=10-{2-[(R)sulfonylamino]-2-oxoethyl}-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic Acid): A New Class of Relaxation Agents for Magnetic Resonance Imaging Applications
    Helvetica Chimica Acta, vol. 88, no. 3, pp. 588–603, 2005
  37. Tunable Imaging of Cells Labeled with MRI-PARACEST Agents
    Angewandte Chemie International Edition, vol. 44, no. 12, pp. 1813–1815, 2005
  38. Highly Sensitive MRI Chemical Exchange Saturation Transfer Agents Using Liposomes
    Angewandte Chemie International Edition, vol. 44, no. 34, pp. 5513–5515, 2005
  39. Iopamidol: Exploring the potential use of a well-established x-ray contrast agent for MRI
    Magnetic Resonance in Medicine, vol. 53, no. 4, pp. 830–834, 2005
  40. HR-MAS of cells: A “cellular water shift” due to water-protein interactions?
    Magnetic Resonance in Medicine, vol. 54, no. 6, pp. 1547–1552, 2005
  41. A Multinuclear NMR Relaxometry Study of Ternary Adducts Formed between Heptadentate GdIII Chelates andL-Lactate
    Chemistry - A European Journal, vol. 11, no. 19, pp. 5531–5537, 2005
  42. Blast from the Past: The Aluminum's Ghost on the Lanthanum Salts
    Current Medicinal Chemistry, vol. 12, no. 14, pp. 1631–1636, 2005
  43. Synthesis of a bifunctional monophosphinic acid DOTA analogue ligand and its lanthanide(iii) complexes. A gadolinium(iii) complex endowed with an optimal water exchange rate for MRI applications
    Organic & Biomolecular Chemistry, vol. 3, no. 1, p. 112, 2005
  44. Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates
    Chemical Communications, no. 4, p. 474, 2005
  45. Dendrimeric Gd(iii) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion
    Chemical Communications, no. 18, p. 2390, 2005
  46. para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents
    Organic & Biomolecular Chemistry, vol. 3, no. 21, p. 3948, 2005
  47. Organic Letters, vol. 6, no. 8, pp. 1201–1204, 2004
  48. Targeting Cells with MR Imaging Probes Based on Paramagnetic Gd(III) Chelates
    Current Pharmaceutical Biotechnology, vol. 5, no. 6, pp. 509–518, 2004
  49. Ln(III)-DOTAMGly Complexes: A Versatile Series to Assess the Determinants of the Efficacy of Paramagnetic Chemical Exchange Saturation Transfer Agents for Magnetic Resonance Imaging Applications
    Investigative Radiology, vol. 39, no. 4, pp. 235–243, 2004
  50. Analytical Chemistry, vol. 76, no. 20, pp. 6012–6016, 2004
  51. Synthesis of new polyoxapolycarboxylic ligands for lanthanide(III) ions complexation
    Tetrahedron Letters, vol. 45, no. 30, pp. 5901–5903, 2004
  52. Inorganic Chemistry, vol. 43, no. 26, pp. 8577–8586, 2004
  53. Inorganic Chemistry, vol. 43, no. 24, pp. 7588–7590, 2004
  54. Proteomics as a tool to improve investigation of substantial equivalence in genetically modified organisms: The case of a virus-resistant tomato
    PROTEOMICS, vol. 4, no. 1, pp. 193–200, 2004
  55. Improved route for the visualization of stem cells labeled with a Gd-/Eu-Chelate as dual (MRI and fluorescence) agent
    Magnetic Resonance in Medicine, vol. 51, no. 5, pp. 938–944, 2004
  56. Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates
    JBIC Journal of Biological Inorganic Chemistry, vol. 10, no. 1, pp. 78–86, 2004
  57. Synthesis and characterization of a macrocyclic Schiff base GdIII complex as a relaxation agent for a faster acquisition of 2H NMR spectra of ethanol
    Inorganica Chimica Acta, vol. 357, no. 5, pp. 1374–1380, 2004
  58. Towards Targeted MRI: New MRI Contrast Agents for Sialic Acid Detection
    Chemistry - A European Journal, vol. 10, no. 20, pp. 5205–5217, 2004
  59. Novel radical-responsive MRI contrast agent based on paramagnetic liposomes
    Magnetic Resonance in Chemistry, vol. 41, no. 8, pp. 585–588, 2003
  60. ?-Cyclodextrin adducts of Gd(III) chelates: useful models for investigating the structural and dynamic determinants of the relaxivity of gadolinium-based systems
    Magnetic Resonance in Chemistry, vol. 41, no. 10, pp. 800–805, 2003
  61. Modulation of the Prototropic Exchange Rate at the Water Molecule Coordinated to a GdIII Ion
    European Journal of Inorganic Chemistry, vol. 2003, no. 11, pp. 2045–2048, 2003
  62. The Water-Exchange Rate in Neutral Heptadentate DO3A-Like GdIII Complexes: Effect of the Basicity at the Macrocyclic Nitrogen Site
    European Journal of Inorganic Chemistry, vol. 2003, no. 19, pp. 3530–3533, 2003
  63. Designing Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Relaxometric Characterization of three Gadolinium(III) Complexes Based on Functionalized Pyridine-Containing Macrocyclic Ligands
    Helvetica Chimica Acta, vol. 86, no. 3, pp. 615–632, 2003
  64. Ternary Complexes between Cationic GdIII Chelates and Anionic Metabolites in Aqueous Solution: An NMR Relaxometric Study
    Chemistry - A European Journal, vol. 9, no. 9, pp. 2102–2109, 2003
  65. The Structure of the Sugar Residue in Glycated Human Serum Albumin and Its Molecular Recognition by Phenylboronate
    Chemistry - A European Journal, vol. 9, no. 10, pp. 2193–2199, 2003
  66. Supramolecular Adducts between Poly-L-arginine and[TmIIIdotp]: A Route to Sensitivity-Enhanced Magnetic Resonance Imaging–Chemical Exchange Saturation Transfer Agents
    Angewandte Chemie International Edition, vol. 42, no. 37, pp. 4527–4529, 2003
  67. Inorganic Chemistry, vol. 42, no. 1, pp. 148–157, 2003
  68. Inorganic Chemistry, vol. 42, no. 8, pp. 2577–2583, 2003
  69. Inorganic Chemistry, vol. 42, no. 16, pp. 4891–4897, 2003
  70. The influence of strong acidic proton donors on the reactivity of H2Ir(CO)Cl(PPh3)2 with D2
    Journal of Molecular Catalysis A: Chemical, vol. 204-205, pp. 371–379, 2003
  71. Modulation of the antioxidant activity of HO· scavengers by albumin binding: a 19F-NMR study
    Biochemical and Biophysical Research Communications, vol. 307, no. 4, pp. 962–966, 2003
  72. Intramolecular hydrogen bonding in transition metal clusters: NMR evidence for an Os–H?H–S interaction in H(µ-H)Os3(CO)10(HSR) (R=ethyl, cyclopentyl)
    Inorganica Chimica Acta, vol. 351, pp. 251–255, 2003
  73. Determination of ferric heme-human serum albumin by 1H NMR relaxometry
    Journal of Inorganic Biochemistry, vol. 95, no. 1, pp. 64–67, 2003
  74. Hyperpolarization transfer from parahydrogen to deuterium via carbon-13
    The Journal of Chemical Physics, vol. 119, no. 17, p. 8890, 2003
  75. In Vitro and In Vivo Study of Solid Lipid Nanoparticles Loaded with Superparamagnetic Iron Oxide
    Journal of Drug Targeting, vol. 11, no. 1, pp. 19–24, 2003
  76. Journal of the American Chemical Society, vol. 125, no. 12, pp. 3458–3470, 2003
  77. Journal of the American Chemical Society, vol. 125, no. 47, pp. 14274–14275, 2003
  78. Journal of the American Chemical Society, vol. 124, no. 32, pp. 9364–9365, 2002
  79. Journal of the American Chemical Society, vol. 124, no. 13, pp. 3431–3442, 2002
  80. Journal of the American Chemical Society, vol. 124, no. 43, pp. 12697–12705, 2002
  81. Organometallics, vol. 21, no. 1, pp. 50–57, 2002
  82. Organometallics, vol. 21, no. 7, pp. 1508–1511, 2002
  83. Controlling the variation of axial water exchange rates in macrocyclic lanthanide(iii) complexesElectronic supplementary information (ESI) available: experimental section. See http://www.rsc.org/suppdata/cc/b2/b202862j/
    Chemical Communications, no. 10, pp. 1120–1121, 2002
  84. Synthesis of the Gd(III) complex with a tetrazole-armed macrocyclic ligand as a potential MRI contrast agent
    Tetrahedron Letters, vol. 43, no. 52, pp. 783–786, 2002
  85. One-step synthesis of a new eight-membered cyclic ligand from glycine, formaldehyde and hypophosphorous acid
    Tetrahedron Letters, vol. 43, no. 46, pp. 8387–8389, 2002
  86. The effect of ligand basicity on the unconventional hydrogen-bond in H(µ-H)Os3(CO)10L (L=amine) derivatives
    Inorganica Chimica Acta, vol. 334, pp. 448–454, 2002
  87. Compartmentalization of a Gadolinium Complex in the Apoferritin Cavity: A Route To Obtain High Relaxivity Contrast Agents for Magnetic Resonance Imaging
    Angewandte Chemie International Edition, vol. 41, no. 6, pp. 1017–1019, 2002
  88. Novel pH-Reporter MRI Contrast Agents
    Angewandte Chemie International Edition, vol. 41, no. 22, pp. 4334–4336, 2002
  89. Innovative magnetic resonance imaging diagnostic agents based on paramagnetic Gd(III) complexes
    Biopolymers, vol. 66, no. 6, pp. 419–428, 2002
  90. Molecular Dynamics Simulation of [Gd(egta)(H2O)]- in Aqueous Solution: Internal Motions of the Poly(amino carboxylate) and Water Ligands, and Rotational Correlation Times
    Chemistry - A European Journal, vol. 8, no. 5, p. 1031, 2002
  91. Heterodinuclear Ln?Na Complexes with an Asymmetric Macrocyclic Compartmental Schiff Base
    Chemistry - A European Journal, vol. 8, no. 17, pp. 3917–3926, 2002
  92. 187Os subspectra in1H and31P{1H} spectra of triosmium carbonyl clusters
    Magnetic Resonance in Chemistry, vol. 40, no. 2, pp. 107–113, 2002
  93. Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations
    Journal of Magnetic Resonance Imaging, vol. 16, no. 4, pp. 394–406, 2002
  94. A paramagnetic probe to localize residues next to carboxylates on protein surfaces
    Journal of Biological Inorganic Chemistry, vol. 7, no. 6, pp. 617–622, 2002
  95. Paramagnetic Lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications
    Magnetic Resonance in Medicine, vol. 47, no. 4, pp. 639–648, 2002
  96. Relaxometric characterization of human hemalbumin
    Journal of Biological Inorganic Chemistry, vol. 6, no. 5-6, pp. 650–658, 2001
  97. Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging
    JBIC Journal of Biological Inorganic Chemistry, vol. 7, no. 1-2, pp. 58–67, 2001
  98. Slow clearance gadolinium-based extracellular and intravascular contrast media for three-dimensional MR angiography
    Journal of Magnetic Resonance Imaging, vol. 13, no. 4, pp. 588–593, 2001
  99. Coordination equilibrium in an Ln(III) macrocyclic chelate modulated by a reversible interaction with a weakly donor substituent
    Magnetic Resonance in Chemistry, vol. 40, no. 1, pp. 87–92, 2001
  100. 1H and17O relaxometric investigations of the binding of Mn(II) ion to human serum albumin
    Magnetic Resonance in Chemistry, vol. 40, no. 1, pp. 41–48, 2001