Robert A. Burne

Robert A. Burne completed his undergraduate studies in microbiology at the Pennsylvania State University and received his Ph.D. degree in microbiology and immunology from the University of Rochester. After a postdoctoral fellowship in microbial physiology, he joined the faculty of the University of Rochester, School of Medicine and Dentistry, in 1990. In August 2001, he became Professor and Chair of the Department of Oral Biology at the University of Florida College of Dentistry. He has served as mentor to over 70 undergraduate and graduate students, postdoctoral fellows, and visiting scholars. He is the author of over 70 peer-reviewed publications detailing his work on the molecular genetics, physiology, and pathogenesis of oral streptococci and actinomycetes. He currently serves on the editorial boards of Infection and Immunity and FEMS Microbiology Letters. He is the recipient of the International Association for Dental Research Hatton and Gies Awards and is a Fellow of the American Association for the Advancement of Sciences.

Biography Updated on 8 May 2007

Articles in Scholarly Journals [Incomplete List]

  1. Biofilm formation in an in vitro model of cochlear implants with removable magnets
    Otolaryngology - Head and Neck Surgery, vol. 136, no. 4, pp. 583–588, 2007
  2. Biofilm formation in cochlear implants with cochlear drug delivery channels in an in vitro model
    Otolaryngology - Head and Neck Surgery, vol. 136, no. 4, pp. 577–582, 2007
  3. Three gene products govern (p)ppGpp production by Streptococcus mutans
    Molecular Microbiology, vol. 65, no. 6, pp. 1568–1581, 2007
  4. The oligopeptide (opp) gene cluster of Streptococcus mutans: identification, prevalence, and characterization
    Oral Microbiology and Immunology, vol. 22, no. 4, pp. 277–284, 2007
  5. The relationship between dental caries status and dental plaque urease activity
    Oral Microbiology and Immunology, vol. 22, no. 1, pp. 61–66, 2007
  6. Influence of Apigenin on gtf Gene Expression in Streptococcus mutans UA159
    Antimicrobial Agents and Chemotherapy, vol. 50, no. 2, pp. 542–546, 2006
  7. Different Roles of EIIABMan and EIIGlc in Regulation of Energy Metabolism, Biofilm Development, and Competence in Streptococcus mutans
    Journal of Bacteriology, vol. 188, no. 11, pp. 3748–3756, 2006
  8. Organization of heat shock dnaK and groE operons of the nosocomial pathogen Enterococcus faecium
    Research in Microbiology, vol. 157, no. 2, pp. 162–168, 2006
  9. Osmotic stress responses of Streptococcus mutans UA159
    FEMS Microbiology Letters, vol. 255, no. 2, pp. 240–246, 2006
  10. The atlA Operon of Streptococcus mutans: Role in Autolysin Maturation and Cell Surface Biogenesis
    Journal of Bacteriology, vol. 188, no. 19, pp. 6877–6888, 2006
  11. Multilevel Control of Competence Development and Stress Tolerance in Streptococcus mutans UA159
    Infection and Immunity, vol. 74, no. 3, pp. 1631–1642, 2006
  12. The Seventh International Conference on the Genetics of Streptococci, Lactococci, and Enterococci
    Journal of Bacteriology, vol. 189, no. 4, pp. 1209–1218, 2006
  13. Influence of BrpA on Critical Virulence Attributes of Streptococcus mutans
    Journal of Bacteriology, vol. 188, no. 8, pp. 2983–2992, 2006
  14. Physiologic Effects of Forced Down-Regulation of dnaK and groEL Expression in Streptococcus mutans
    Journal of Bacteriology, vol. 189, no. 5, pp. 1582–1588, 2006
  15. A novel signal transduction system and feedback loop regulate fructan hydrolase gene expression in Streptococcus mutans
    Molecular Microbiology, vol. 62, no. 1, pp. 187–200, 2006
  16. Regulation and Physiologic Significance of the Agmatine Deiminase System of Streptococcus mutans UA159
    Journal of Bacteriology, vol. 188, no. 3, pp. 834–841, 2006
  17. Characterization of cis-Acting Sites Controlling Arginine Deiminase Gene Expression in Streptococcus gordonii
    Journal of Bacteriology, vol. 188, no. 3, pp. 941–949, 2006
  18. Role of HtrA in Growth and Competence of Streptococcus mutans UA159
    Journal of Bacteriology, vol. 187, no. 9, pp. 3028–3038, 2005
  19. A Hypothetical Protein of Streptococcus mutans Is Critical for Biofilm Formation
    Infection and Immunity, vol. 73, no. 5, pp. 3147–3151, 2005
  20. Trigger Factor in Streptococcus mutans Is Involved in Stress Tolerance, Competence Development, and Biofilm Formation
    Infection and Immunity, vol. 73, no. 1, pp. 219–225, 2005
  21. Characteristics of strains lacking the MazEF and RelBE toxin–antitoxin modules
    FEMS Microbiology Letters, vol. 253, no. 2, pp. 251–257, 2005
  22. RegM is required for optimal fructosyltransferase and glucosyltransferase gene expression in
    FEMS Microbiology Letters, vol. 240, no. 1, pp. 75–79, 2004
  23. Transcriptional analysis of the groE and dnaK heat-shock operons of Enterococcus faecalis
    Research in Microbiology, vol. 155, no. 4, pp. 252–258, 2004
  24. Effects of RelA on Key Virulence Properties of Planktonic and Biofilm Populations of Streptococcus mutans
    Infection and Immunity, vol. 72, no. 3, pp. 1431–1440, 2004
  25. Bacterial Biofilms May Contribute to Persistent Cochlear Implant Infection
    Otology & Neurotology, vol. 25, no. 6, pp. 953–957, 2004
  26. Galactose Metabolism by Streptococcus mutans
    Applied and Environmental Microbiology, vol. 70, no. 10, pp. 6047–6052, 2004
  27. Characterization of the Arginine Deiminase Operon of Streptococcus rattus FA-1
    Applied and Environmental Microbiology, vol. 70, no. 3, pp. 1321–1327, 2004
  28. Control of Expression of the Arginine Deiminase Operon of Streptococcus gordonii by CcpA and Flp
    Journal of Bacteriology, vol. 186, no. 8, pp. 2511–2514, 2004
  29. Adaptive Acid Tolerance Response of Streptococcus sobrinus
    Journal of Bacteriology, vol. 186, no. 19, pp. 6383–6390, 2004
  30. Analysis of an Agmatine Deiminase Gene Cluster in Streptococcus mutans UA159
    Journal of Bacteriology, vol. 186, no. 6, pp. 1902–1904, 2004
  31. LuxS-Mediated Signaling in Streptococcus mutans Is Involved in Regulation of Acid and Oxidative Stress Tolerance and Biofilm Formation
    Journal of Bacteriology, vol. 186, no. 9, pp. 2682–2691, 2004
  32. Characterization of Streptococcus mutans Strains Deficient in EIIABMan of the Sugar Phosphotransferase System
    Applied and Environmental Microbiology, vol. 69, no. 8, pp. 4760–4769, 2003
  33. Role of Urease Enzymes in Stability of a 10-Species Oral Biofilm Consortium Cultivated in a Constant-Depth Film Fermenter
    Infection and Immunity, vol. 71, no. 12, pp. 7188–7192, 2003
  34. Identification and Characterization of the Nickel Uptake System for Urease Biogenesis in Streptococcus salivarius 57.I
    Journal of Bacteriology, vol. 185, no. 23, pp. 6773–6779, 2003
  35. Pathways for lactose/galactose catabolism by Streptococcus salivarius
    FEMS Microbiology Letters, vol. 209, no. 1, pp. 75–79, 2002
  36. Functional Genomics Approach to Identifying Genes Required for Biofilm Development by Streptococcus mutans
    Applied and Environmental Microbiology, vol. 68, no. 3, pp. 1196–1203, 2002
  37. Analysis of cis- and trans-Acting Factors Involved in Regulation of the Streptococcus mutans Fructanase Gene (fruA)
    Journal of Bacteriology, vol. 184, no. 1, pp. 126–133, 2002
  38. Regulation and Physiological Significance of ClpC and ClpP in Streptococcus mutans
    Journal of Bacteriology, vol. 184, no. 22, pp. 6357–6366, 2002
  39. Pathways for lactose/galactose catabolism by Streptococcus salivarius
    FEMS Microbiology Letters, vol. 209, no. 1, pp. 72–76, 2002
  40. Construction of a New Integration Vector for Use in Streptococcus mutans
    Plasmid, vol. 45, no. 1, pp. 31–36, 2001
  41. Genetic and Physiologic Analysis of the groE Operon and Role of the HrcA Repressor in Stress Gene Regulation and Acid Tolerance in Streptococcus mutans
    Journal of Bacteriology, vol. 183, no. 20, pp. 6074–6084, 2001
  42. Roles of Fructosyltransferase and Levanase-Sucrase of Actinomyces naeslundii in Fructan and Sucrose Metabolism
    Infection and Immunity, vol. 69, no. 9, pp. 5395–5402, 2001
  43. Analysis of Urease Expression in Actinomyces naeslundii WVU45
    Infection and Immunity, vol. 68, no. 12, pp. 6670–6676, 2000
  44. Characterization of Recombinant, Ureolytic Streptococcus mutans Demonstrates an Inverse Relationship between Dental Plaque Ureolytic Capacity and Cariogenicity
    Infection and Immunity, vol. 68, no. 5, pp. 2621–2629, 2000
  45. Characterization of the Fructosyltransferase Gene of Actinomyces naeslundii WVU45
    Journal of Bacteriology, vol. 182, no. 13, pp. 3649–3654, 2000
  46. Dual Functions of Streptococcus salivarius Urease
    Journal of Bacteriology, vol. 182, no. 16, pp. 4667–4669, 2000
  47. Bacterial ureases in infectious diseases
    Microbes and Infection, vol. 2, no. 5, pp. 533–542, 2000
  48. Regulation of urease gene expression by Streptococcus salivarius growing in biofilms
    Environmental Microbiology, vol. 2, no. 2, pp. 169–177, 2000
  49. Methods in Cell Science, vol. 20, no. 1/4, pp. 181–190, 1998
  50. Transcriptional analysis of the Streptococcus mutans hrcA, grpE and dnaK genes and regulation of expression in response to heat shock and environmental acidification
    Molecular Microbiology, vol. 25, no. 02, pp. 329–341, 1997
  51. Identification of a fliG homologue in treponema denticola
    Gene, vol. 161, no. 1, pp. 69–73, 1995
  52. Modulation of rat cortical area 17 neuronal responses to moving visual stimuli during norepinephrine and serotonin microiontophoresis
    Brain Research, vol. 514, no. 2, pp. 276–292, 1990
  53. Modification of the visual response properties of cerebellar neurons by norepinephrine
    Brain Research, vol. 514, no. 2, pp. 259–275, 1990
  54. Cloning and expression of a Streptococcus mutans glucosyltransferase gene in Bacillus subtilis
    Gene, vol. 47, no. 2-3, pp. 201–209, 1986
  55. Response properties of neurons in the visual cortex of the rat
    Experimental Brain Research, vol. 53, no. 2, 1984
  56. Electrophysiologic identification of projections from the midbrain to the paraflocculus and midvermis in the rat
    Brain Research Bulletin, vol. 12, no. 3, pp. 267–274, 1984
  57. Visual cortical projections to the paraflocculus in the rat
    Experimental Brain Research, vol. 49, no. 1, 1983
  58. The distribution of neocortical projection neurons in the locus coeruleus
    The Journal of Comparative Neurology, vol. 217, no. 4, pp. 418–431, 1983
  59. Distribution and morphology of functionally identified neurons in the visual cortex of the rat
    Brain Research, vol. 261, no. 1, pp. 21–29, 1983
  60. Evidence suggesting that both the corticopontine and cerebellopontine systems are each composed of two separate neuronal populations: An electron microscopic and horseradish peroxidase study in the rat
    The Journal of Comparative Neurology, vol. 195, no. 2, pp. 221–242, 1981
  61. Subcortical projections to layer I of the visual cortex, area 17, of the rat
    Experimental Brain Research, vol. 41, no. 2, 1981
  62. Receptive field properties of neurons in the visual cortex of the rat
    Neuroscience Letters, vol. 27, no. 3, pp. 291–296, 1981
  63. The tectopontine projection in the rat with comments on visual pathways to the basilar pons
    The Journal of Comparative Neurology, vol. 202, no. 2, pp. 287–307, 1981
  64. The pontocerebellar system in the rat: An HRP study. II. Hemispheral components
    The Journal of Comparative Neurology, vol. 197, no. 4, pp. 559–577, 1981
  65. The pontocerebellar system in the rat: An HRP study. I. Posterior vermis
    The Journal of Comparative Neurology, vol. 197, no. 4, pp. 543–558, 1981
  66. Projections of the sensorimotor cortex to the basilar pontine nuclei in the rat: an autoradiographic study
    Brain Research, vol. 145, no. 2, pp. 347–354, 1978
  67. Visual corticopontine input to the paraflocculus: a combined autoradiographic and horseradish peroxidase study
    Brain Research, vol. 143, no. 1, pp. 139–146, 1978
  68. The organization of the pontine projection to lateral cerebellar areas in the rat: dual zones in the pons
    Brain Research, vol. 139, no. 2, pp. 340–347, 1978