Igea D'Agnano is a Senior Researcher at the Institute of Neurobiology and Molecular Medicine, National Research Council. She graduated in biology in 1986 at the University of Rome La Sapienza, Rome, Italy. She completed her Ph.D. degree in clinical pathology in 1991 at the University of Rome La Sapienza, Rome, Italy. Since 1992, she has been on staff at the National Research Council. In 1992, she has been a visiting scientist at the Laboratory of Professor Bruno Calabretta, Department of Microbiology of the Jefferson Cancer Institute, Jefferson University, Philadelphia (USA). From 2004 until 2007, she has taught antitumoral chemotherapy of the medical biotechnology and molecular medicine course, Faculty of Medicine/University of Milan, Italy. Since many years, her main field of interest is the preclinical experimental chemotherapy, in particular the development of new antitumoral therapeutic strategies. She focused her recent research on developing strategies to inhibit the MYC oncogene in different cancer models using different approaches: antisense oligonucleotides, and oligopeptides. This allowed her to investigate the intracellular molecular pathways involved in the inhibition of the Myc protein activity in cellular processes such as cell cycle regulation, activation of apoptosis, and cell differentiation.
Biography Updated on 12 December 2010