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Ernest Borden
Articles in Scholarly Journals [Incomplete List]
Gene Modulatory Effects, Pharmacokinetics, and Clinical Tolerance of Interferon-a1b: A Second Member of the Interferon-a Family
Clinical Pharmacology & Therapeutics, vol. 81, no. 3, Article ID 6100081, 7 pages, 2007
Methylthioadenosine phosphorylase gene deletions are frequently detected by fluorescence in situ hybridization in conventional chondrosarcomas
Cancer Genetics and Cytogenetics, vol. 166, no. 2, pp. 95–100, 2006
Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer
British Journal of Cancer, vol. 94, no. 10, Article ID 6603099, 6 pages, 2006
Journal of Interferon & Cytokine Research, vol. 26, no. 11, pp. 800–803, 2006
Phase II Trial of Gemcitabine as First Line Chemotherapy in Patients With Metastatic or Unresectable Soft Tissue Sarcoma
American Journal of Clinical Oncology, vol. 29, no. 1, pp. 59–61, 2006
Efficacy of SSG and SSG/IFNα2 against human prostate cancer xenograft tumors in mice: a role for direct growth inhibition in SSG anti-tumor action
Cancer Chemotherapy and Pharmacology, vol. 60, no. 3, pp. 341–349, 2006
Phase I trial of three-weekly Docetaxel, Carboplatin and oral lenalidomide (Revlimid®) in patients with advanced solid tumors
Investigational New Drugs, vol. 25, no. 3, pp. 211–216, 2006
Expression of RASSF1A, an Epigenetically Silenced Tumor Suppressor, Overcomes Resistance to Apoptosis Induction by Interferons
Cancer Research, vol. 66, no. 5, pp. 2785–2793, 2006
Circulating Tumor Cells versus Imaging--Predicting Overall Survival in Metastatic Breast Cancer
Clinical Cancer Research, vol. 12, no. 21, pp. 6403–6409, 2006
Overcoming Resistance to Interferon-Induced Apoptosis of Renal Carcinoma and Melanoma Cells by DNA Demethylation
Journal of Clinical Oncology, vol. 24, no. 23, pp. 3771–3779, 2006
A phase I clinical trial of a ribozyme-based angiogenesis inhibitor targeting vascular endothelial growth factor receptor-1 for patients with refractory solid tumors
Molecular Cancer Therapeutics, vol. 4, no. 6, pp. 948–955, 2005
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells
Biochemical and Biophysical Research Communications, vol. 336, no. 2, pp. 496–506, 2005
Review: Milstein Award Lecture: Interferons and Cancer: Where from Here?
Journal of Interferon
Cytokine Research, vol. 25, no. 9, pp. 511–527, 2005
Metastatic Uveal Melanoma
Ophthalmology Clinics of North America, vol. 18, no. 1, pp. 143–150, 2005
Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
Cell Death and Differentiation, vol. 11, no. 8, Article ID 4401416, 8 pages, 2004
Reverse Signaling through Membrane-bound Interleukin-15
Journal of Biological Chemistry, vol. 279, no. 40, pp. 42192–42201, 2004
Natural Soluble Interleukin-15R Is Generated by Cleavage That Involves the Tumor Necrosis Factor- -converting Enzyme (TACE/ADAM17)
Journal of Biological Chemistry, vol. 279, no. 39, pp. 40368–40375, 2004
Retinoic acid-inducible gene-I is induced by interferon-γ and regulates the expression of interferon-γ stimulated gene 15 in MCF-7 cells
Biochemistry and Cell Biology, vol. 82, no. 3, pp. 401–405, 2004
Estrogen and Progesterone Receptor Expression in Uterine and Extrauterine Leiomyosarcomas
Applied Immunohistochemistry & Molecular Morphology, pp. 338–341, 2004
Phase 2 Trial of Interferon-Beta as Second-Line Treatment of Ovarian Cancer, Fallopian Tube Cancer, or Primary Carcinoma of the Peritoneum
Oncology, vol. 66, no. 5, pp. 343–346, 2004
Phase II randomized trial of cisplatin and WR-2721 versus cisplatin alone for metastatic melanoma
Melanoma Research, vol. 13, no. 6, pp. 619–626, 2003
Journal of Immunotherapy, vol. 26, no. 3, pp. 202–211, 2003
IFN-2b and Thalidomide Synergistically Inhibit Tumor-Induced Angiogenesis
Journal of Interferon
Cytokine Research, vol. 23, no. 1, pp. 3–10, 2003
Novel Growth and Death Related Interferon-Stimulated Genes (ISGs) in Melanoma: Greater Potency of IFN- Compared with IFN-2
Journal of Interferon
Cytokine Research, vol. 23, no. 12, pp. 745–756, 2003
Apoptosis, vol. 8, no. 3, pp. 237–249, 2003
High-throughput Immunoblotting. UBIQUITIN-LIKE PROTEIN ISG15 MODIFIES KEY REGULATORS OF SIGNAL TRANSDUCTION
Journal of Biological Chemistry, vol. 278, no. 19, pp. 16608–16613, 2003
Suppression of NF- B Survival Signaling by Nitrosylcobalamin Sensitizes Neoplasms to the Anti-tumor Effects of Apo2L/TRAIL
Journal of Biological Chemistry, vol. 278, no. 41, pp. 39461–39469, 2003
New and modified interferon alfas: Preclinical and clinical data
Current Oncology Reports, vol. 5, no. 2, pp. 108–113, 2003
Identification of X-linked Inhibitor of Apoptosis-associated Factor-1 as an Interferon-stimulated Gene That Augments TRAIL Apo2L-induced Apoptosis
Journal of Biological Chemistry, vol. 277, no. 32, pp. 28504–28511, 2002
Resistance to Interferons in Melanoma Cells Does Not Correlate with the Expression or Activation of Signal Transducer and Activator of Transcription 1 (Stat1)
Journal of Interferon
Cytokine Research, vol. 22, no. 5, pp. 603–613, 2002
Final analysis of the ECOG I-COPA trial (E6484) in patients with non-Hodgkin’s lymphoma treated with interferon alfa (IFN-a2a) plus an anthracycline-based induction regimen
Leukemia, vol. 15, no. 7, Article ID 2402161, 4 pages, 2001
Reducing primary melanoma mortality
Current Oncology Reports, vol. 2, no. 4, pp. 289–291, 2000
Neuropsychological effects of interferon ?-1a in relapsing multiple sclerosis
Annals of Neurology, vol. 48, no. 6, pp. 885–892, 2000
Second-generation interferons for cancer: clinical targets
Seminars in Cancer Biology, vol. 10, no. 2, pp. 125–144, 2000
Pharmaceutical Research, vol. 15, no. 1, pp. 2–3, 1998
Pharmaceutical Research, vol. 15, no. 1, pp. 1–1, 1998
Investigational New Drugs, vol. 16, no. 3, pp. 259–263, 1998
American Journal of Clinical Oncology, vol. 21, no. 5, pp. 509–512, 1998
Molecular and Cellular Biochemistry, vol. 167, no. 1-2, pp. 169–177, 1997
Effects of tamoxifen and interferon-β or the combination on tumor-induced angiogenesis
International Journal of Cancer, vol. 71, no. 3, pp. 456–461, 1997
Immunoregulatory properties of ISG15, an interferon-induced cytokine
Proceedings of the National Academy of Sciences, vol. 93, no. 1, pp. 211–215, 1996
Modulation of Interferon (IFN)-inducible Gene Expression by Retinoic Acid
Journal of Biological Chemistry, vol. 271, no. 18, pp. 10508–10514, 1996
Hematologic and Immunologic Evaluation of Recombinant Human Interleukin-6 in Patients with Advanced Malignant Disease: Evidence for Monocyte Activation
Journal of Immunotherapy, vol. 19, no. 3, pp. 231–243, 1996
Transcriptional induction of genes by IFN-ß in mouse cells is regulated by a transcription factor similar to human ISGF-3
Antiviral Research, vol. 25, no. 2, pp. 91–103, 1994
Molecular diagnosis and monitoring of leukemia and lymphoma
Leukemia Research, vol. 17, no. 12, pp. 1073–1078, 1993
Prognostic factors in metastatic melanoma
Cancer, vol. 71, no. 10, pp. 2995–3005, 1993
Human recombinant interferon-?SER and tamoxifen: growth suppressive effects for the human breast carcinoma MCF-7 grown in the athymic mouse
Breast Cancer Research and Treatment, vol. 25, no. 2, pp. 141–150, 1993
Pharmacodynamics of Biological Response In Vivo After Single and Multiple Doses of Interferon?????
Journal of Immunotherapy, vol. 13, no. 3, pp. 191–200, 1993
Inhibitory Effects of Cytokines on Vascular Endothelial Cells: Synergistic Interactions Among Interferon-??, Tumor Necrosis Factor-??, and Interleukin-1
Journal of Immunotherapy, vol. 12, no. 4, p. 286, 1992
Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor
Cancer, vol. 69, no. 2, pp. 562–571, 1992
Interferons: Pleiotropic cellular modulators
Clinical Immunology and Immunopathology, vol. 62, no. 1, pp. S18–S24, 1992
An extended phase II trial of ifosfamide plus mesna in malignant mesothelioma
Investigational New Drugs, vol. 10, no. 4, pp. 337–343, 1992
Applications of monoclonal antibodies and recombinant cytokines for the treatment of human colorectal and other carcinomas
Journal of Surgical Oncology, vol. 48, no. S2, pp. 9–13, 1991
Immunological Effects of Levamisole In Vitro
Journal of Immunotherapy, vol. 10, no. 5, pp. 297–306, 1991
Randomized comparison of doxorubicin and vindesine to doxorubicin for patients with metastatic soft-tissue sarcomas
Cancer, vol. 66, no. 5, pp. 862–867, 1990
Inhibition of hormone-dependent and independent breast cancer cell growthin vivo andin vitro with the antiestrogen toremifene and recombinant human interferon-a2
Breast Cancer Research and Treatment, vol. 15, no. 2, pp. 95–101, 1990
The appearance of hypodense eosinophils during interleukin-2 treatment
Journal of Allergy and Clinical Immunology, vol. 85, no. 3, pp. 557–566, 1990
Interferons and indoleamine 2,3-dioxygenase: Role in antimicrobial and antitumor effects
Experientia, vol. 45, no. 6, pp. 535–541, 1989
Pathologic analysis of advanced adult soft tissue sarcomas, bone sarcomas, and mesotheliomas. The eastern cooperative oncology group (ECOG) experience
Cancer, vol. 64, no. 2, pp. 484–490, 1989
Interferons: Biological and clinical effects
Seminars in Surgical Oncology, vol. 5, no. 6, pp. 391–401, 1989
Effects of interferons in neoplastic diseases of man
Pharmacology & Therapeutics, vol. 37, no. 2, pp. 213–229, 1988
Plasma lipoprotein changes in humans induced by β-interferon
Atherosclerosis, vol. 67, no. 2-3, pp. 261–267, 1987
Assessment of the antigenic response in humans to a recombinant mutant interferon beta
Journal of Clinical Immunology, vol. 7, no. 5, pp. 365–375, 1987
Antiproliferative activity of recombinant interferons alpha and beta for human renal carcinoma cells: Supra-additive activity with elevated temperature or vinblastine
World Journal of Urology, vol. 3, no. 4, pp. 230–233, 1986
Decreases in serum high-density-lipoprotein cholesterol and total cholesterol resulting from naturally produced and recombinant DNA-derived leukocyte interferons
Metabolism, vol. 33, no. 5, pp. 400–404, 1984
Effect of influenza A virus on leukocyte histamine release
Journal of Allergy and Clinical Immunology, vol. 71, no. 4, pp. 382–388, 1983
Effects of levamisole on human natural killer and killer cell activity and production of interferons
Immunopharmacology, vol. 5, no. 1, pp. 11–18, 1982
Augmentation in the infectivity of SV40 virus DNA by amphotericin B methyl ester
Archives of Virology, vol. 69, no. 2, pp. 161–165, 1981
Enhancement in recall antigen responses by frequent, repetitive skin testing with candida, mumps, and streptokinase-streptodornase in 38 normal adults
Cancer Immunology Immunotherapy, vol. 10, no. 1, pp. 27–31, 1980
Recommendations for clinical protocol development and definition of therapeutic response for soft-tissue sarcomas
Cancer, vol. 46, no. 4, pp. 796–800, 1980
Hexamethylmelamine treatment of sarcomas and lymphomas
Medical and Pediatric Oncology, vol. 3, no. 4, pp. 401–406, 1977
Inhibition by streptovaricins of rauscher leukemia virus splenomegaly
International Journal of Cancer, vol. 14, no. 6, pp. 817–825, 1974
SELECTIVE INHIBITION OF VIRAL FUNCTIONS: THE ANTIVIRAL ACTION OF INTERFERON AND STREPTOVARICIN
Medicine, vol. 51, no. 3, pp. 181–188, 1972
VIRAL CHEMOTHERAPY: ITS PROMISE AND PROBLEMS
Medicine, vol. 51, no. 3, pp. 189–190, 1972
DEPRESSION OF INTERFERON PRODUCTION AFTER A.L.S. TREATMENT
The Lancet, vol. 294, no. 7633, pp. 1307–1308, 1969