Julian J. Raffoul
Julian J. Raffoul is a Resident Physician in internal medicine at Emory University School of Medicine, Atlanta, Ga, USA. Dr. Raffoul has been conducting diet and cancer research for over 10 years, having completing his M.D. and Ph.D. degrees in nutrition and cancer biology at Wayne State University, Detroit, Mich, USA, and his Postdoctoral Fellowship in nutrition and cancer therapy at the Karmanos Cancer Institute, Detroit, Mich, USA. His research is focused on understanding the link between diet and cancer biology and treatment by studying the effect of macronutrients, micronutrients, and phytochemicals on the cellular DNA damage and repair response. Dr. Raffoul has published extensively on the role of DNA base excision repair in the molecular pathogenesis of aging, cancer, and on the combination of radiation with cancer chemopreventive agents for the treatment of prostate and renal cell cancers. He has characterized the effect of age, caloric restriction, folate deficiency, and the role of soy isoflavones on the expression and activity of cell-signaling pathways, including NF-kappaB, and on DNA repair enzymes, such as DNA polymerase beta, and apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1), both in vitro and in vivo. His work has been recognized through publication in prestigious journals such as Cancer Research and the Journal of Biological Chemistry. As a Physician-Scientist, Dr. Raffoul conducts translational “bench-to-bedside” research, bringing his laboratory research findings into clinical practice while pursuing several preclinical and clinical trials. Dr. Raffoul serves as an Editor for multiple peer-reviewed journals, including the International Journal of Cancer, Cancer Epidemiology, Planta Medica, and Radiation Oncology and is a Member of the American Medical Association, the American Society for Nutrition, the American Association for Cancer Research, and the NIH DNA Repair Interest Group.
Biography Updated on 9 August 2012