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Cahir O'Kane
Articles in Scholarly Journals [Incomplete List]
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
Nature Chemical Biology, vol. 3, no. 6, Article ID nchembio883, 7 pages, 2007
Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules
Nature Neuroscience, vol. 10, no. 2, Article ID nn1841, 8 pages, 2007
Rapamycin pre-treatment protects against apoptosis
Human Molecular Genetics, vol. 15, no. 7, pp. 1209–1216, 2006
Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights
Human Molecular Genetics, vol. 14, no. 10, pp. 1261–1270, 2005
Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway
Human Molecular Genetics, vol. 14, no. 20, pp. 3003–3011, 2005
Rapamycin alleviates toxicity of different aggregate-prone proteins
Human Molecular Genetics, vol. 15, no. 3, pp. 433–442, 2005
Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion
Human Molecular Genetics, vol. 15, no. 3, pp. 453–465, 2005
Stereotypic and random patterns of connectivity in the larval mushroom body calyx of Drosophila
Proceedings of the National Academy of Sciences, vol. 102, no. 52, pp. 19027–19032, 2005
Dynein mutations impair autophagic clearance of aggregate-prone proteins
Nature Genetics, vol. 37, no. 7, Article ID ng1591, 5 pages, 2005
Shaw potassium channel genes inDrosophila
Journal of Neurobiology, vol. 63, no. 3, pp. 235–254, 2005
ISOGENIC AUTOSOMES TO BE APPLIED IN OPTIMAL SCREENING FOR NOVEL MUTANTS WITH VIABLE PHENOTYPES IN DROSOPHILA MELANOGASTER
Journal of Neurogenetics, vol. 19, no. 2, pp. 57–85, 2005
The DrosDel Collection: A Set of P-Element Insertions for Generating Custom Chromosomal Aberrations in Drosophila melanogaster
Genetics, vol. 167, no. 2, pp. 797–813, 2004
Cullin-3 regulates pattern formation, external sensory organ development and cell survival during development
Mechanisms of Development, vol. 121, no. 12, pp. 1495–1507, 2004
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Nature Genetics, vol. 36, no. 6, Article ID ng1362, 10 pages, 2004
Modelling human diseases in Drosophila and Caenorhabditis
Seminars in Cell & Developmental Biology, vol. 14, no. 1, pp. 3–10, 2003
Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation
The Journal of Cell Biology, vol. 160, no. 6, pp. 899–908, 2003
From the Cover: Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability
Proceedings of the National Academy of Sciences, vol. 99, no. 21, pp. 13867–13872, 2002
Cell ablation using wild-type and cold-sensitive ricin-a chain indrosophila embryonic mesoderm
genesis, vol. 34, no. 1-2, pp. 132–134, 2002
Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input inDrosophila
Journal of Neurobiology, vol. 50, no. 3, pp. 221–233, 2002
The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila
Cell, vol. 106, no. 3, pp. 355–366, 2001
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila
Genes & Development, vol. 15, no. 22, pp. 2967–2979, 2001
Characterisation of the gene for Drosophila amphiphysin
Gene, vol. 241, no. 1, pp. 167–174, 2000
Featured Organism:Drosophila melanogaster
Yeast, vol. 17, no. 2, pp. 146–153, 2000
Sexual behaviour: Courting dissatisfaction
Current Biology, vol. 9, no. 8, pp. R289–R292, 1999
Identification and characterization of the gene for Drosophila L3 ribosomal protein
Gene, vol. 212, no. 1, pp. 119–125, 1998
Identification and characterization of kraken, a gene encoding a putative hydrolytic enzyme in Drosophila melanogaster
Gene, vol. 222, no. 2, pp. 195–201, 1998
The Fascination of the Drosophila NMJ
Trends in Genetics, vol. 13, no. 3, pp. 85–87, 1997
Identification and characterization of the gene for Drosophila S20 ribosomal protein
Gene, vol. 200, no. 1-2, pp. 85–89, 1997
Genetic Feminization of Pheromones and Its Behavioral Consequences in Drosophila Males
Science, vol. 276, no. 5318, pp. 1555–1558, 1997
Activation of protein kinase A-independent pathways by Gsalpha in Drosophila
Proceedings of the National Academy of Sciences, vol. 93, no. 25, pp. 14542–14547, 1996
Associative Learning Disrupted by Impaired Gs Signaling in Drosophila Mushroom Bodies
Science, vol. 274, no. 5295, pp. 2104–2107, 1996
Inducible ternary control of transgene expression and cell ablation in Drosophila
Development Genes and Evolution, vol. 206, no. 1, pp. 14–24, 1996
Syntaxin and synaptohrevin function downstream of vesicle docking in drosophila
Neuron, vol. 15, no. 3, pp. 663–673, 1995
Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects
Neuron, vol. 14, no. 2, pp. 341–351, 1995
Selective cell ablation and genetic surgery
Current Opinion in Genetics & Development, vol. 2, no. 4, pp. 602–607, 1992
Use of a cytoplasmically localised P-lacZ fusion to identify cell shapes by enhancer trapping inDrosophila
Roux's Archives of Developmental Biology, vol. 200, no. 6, pp. 306–311, 1991
P-element-mediated enhancer detection: a versatile method to study development in Drosophila.
Genes & Development, vol. 3, no. 9, pp. 1288–1300, 1989
P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila.
Genes & Development, vol. 3, no. 9, pp. 1301–1313, 1989
Detection in situ of Genomic Regulatory Elements in Drosophila
Proceedings of the National Academy of Sciences, vol. 84, no. 24, pp. 9123–9127, 1987
Mapping of the gene for endo-beta-1,3-1,4-glucanase of Bacillus subtilis
FEMS Microbiology Letters, vol. 29, no. 1-2, pp. 135–139, 1985