Hermann Brenner

Hermann Brenner was born in 1958 in Sindelfingen, Germany. During 1978–1985, he worked at the Medical School, University of Tübingen and Univerity of Marburg. In 1985, he obtained the M.D. degree from the University of Tübingen. From 1985 to 1987, he was a Resident of internal medicine and family medicine. Between 1987–1988, he served at the School of Public Health, University of North Carolina at Chapel Hill, USA. Brenner received his M.P.H. degree in epidemiology from the UNC School of Public Health in 1988. In 1989–1990, he worked as an Epidemiologist at Cancer Registry of Saarland, and during 1990–1993, he was the Head of the Unit of Epidemiology, University of Ulm. He also served as an Associate Professor of public health and epidemiology at the University of Munich in 1993–1994. Between 1995–2000, he was a Professor of epidemiology and Chair of the Department of Epidemiology, University of Ulm, and during 2000–2005, he served as a Professor of epidemiology as well as the Chair of the Department of Epidemiology, German Centre for Research on Ageing, Heidelberg. In 2006, he was also a Professor of epidemiology and Chair of the Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg. He received multiple research awards, including Herman A. Tyroler Distinguished Alumni Award, University of North Carolina at Chapel Hill, USA, in 2001.

Biography Updated on 25 June 2008

Personal Home Page

http://www.dkfz.de/en/klinepi/index.html

Articles in Scholarly Journals [Incomplete List]

  1. Periodversus cohort modeling of up-to-date cancer survival
    International Journal of Cancer, vol. 122, no. 4, pp. 898–904, 2008
  2. Ongoing Improvement in Outcomes for Patients Diagnosed as Having Non-Hodgkin Lymphoma From the 1990s to the Early 21st Century
    Archives of Internal Medicine, vol. 168, no. 5, pp. 469–476, 2008
  3. The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis
    International Journal of Cancer, vol. 122, no. 11, pp. 2573–2580, 2008
  4. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
    Nature Genetics, vol. 40, no. 5, Article ID ng.133, 6 pages, 2008
  5. Ongoing improvement in long-term survival of patients with Hodgkin disease at all ages and recent catch-up of older patients
    Blood, vol. 111, no. 6, pp. 2977–2983, 2008
  6. Recent major improvement in long-term survival of younger patients with multiple myeloma
    Blood, vol. 111, no. 5, pp. 2521–2526, 2008
  7. Improvements in survival of adults diagnosed with acute myeloblastic leukemia in the early 21st century
    Haematologica, vol. 93, no. 4, pp. 594–600, 2008
  8. Recent Major Progress in Long-Term Cancer Patient Survival Disclosed by Modeled Period Analysis
    Journal of Clinical Oncology, vol. 25, no. 22, pp. 3274–3280, 2007
  9. Maximizing the Benefits of Model-Based Period Analysis of Cancer Patient Survival
    Cancer Epidemiology Biomarkers & Prevention, vol. 16, no. 8, pp. 1675–1681, 2007
  10. Mutant-Enriched PCR and Allele-Specific Hybridization Reaction to Detect K-ras Mutations in Stool DNA: High Prevalence in a Large Sample of Older Adults
    Clinical Chemistry, vol. 53, no. 4, pp. 787–790, 2007
  11. Blood Markers for Early Detection of Colorectal Cancer: A Systematic Review
    Cancer Epidemiology Biomarkers & Prevention, vol. 16, no. 10, pp. 1935–1953, 2007
  12. Recent cancer survival in Europe: a 2000–02 period analysis of EUROCARE-4 data
    The Lancet Oncology, vol. 8, no. 9, pp. 784–796, 2007
  13. Long-term and short-term alcohol consumption and levels of C-reactive protein?
    International Journal of Cardiology, vol. 121, no. 2, pp. 224–226, 2007
  14. Polymorphisms in the insulin like growth factor 1 and IGF binding protein 3 genes and risk of colorectal cancer
    Cancer Detection and Prevention, vol. 31, no. 5, pp. 408–416, 2007
  15. Adiponectin polymorphisms, cord blood levels of adiponectin, and body composition
    Journal of Allergy and Clinical Immunology, vol. 120, no. 2, pp. 469–470, 2007
  16. Model based hybrid analysis of cancer patient survival
    European Journal of Cancer, vol. 43, no. 5, pp. 921–927, 2007
  17. Household contacts were key factor for children's colonization with resistant Escherichia coli in community setting
    Journal of Clinical Epidemiology, vol. 60, no. 11, pp. 1149–1155, 2007
  18. Heavy Physical Activity: Risk or Protective Factor for Cardiovascular Disease? A Life Course Perspective
    Annals of Epidemiology, vol. 17, no. 6, pp. 417–424, 2007
  19. Helicobacter pylori infection, interleukin-1 gene polymorphisms and the risk of colorectal cancer: Evidence from a case-control study in Germany
    European Journal of Cancer, vol. 43, no. 8, pp. 1283–1289, 2007
  20. Epidemiologic findings on serologically defined chronic atrophic gastritis strongly depend on the choice of the cutoff-value
    International Journal of Cancer, vol. 121, no. 12, pp. 2782–2786, 2007
  21. Patients with previous cancer should not be excluded in international comparative cancer survival studies
    International Journal of Cancer, vol. 121, no. 10, pp. 2274–2278, 2007
  22. Individual and joint use of statins and low-dose aspirin and risk of colorectal cancer: A population-based case–control study
    International Journal of Cancer, vol. 121, no. 6, pp. 1325–1330, 2007
  23. Cancer survival in Germany and the United States at the beginning of the 21st century: An up-to-date comparison by period analysis
    International Journal of Cancer, vol. 121, no. 2, pp. 395–400, 2007
  24. Validity of Self-Reported Endoscopies of the Large Bowel and Implications for Estimates of Colorectal Cancer Risk
    American Journal of Epidemiology, vol. 166, no. 2, pp. 130–136, 2007
  25. Up-to-date monitoring of childhood cancer long-term survival in Europe: methodology and application to all forms of cancer combined
    Annals of Oncology, vol. 18, no. 9, pp. 1561–1568, 2007
  26. Up-to-date monitoring of childhood cancer long-term survival in Europe: leukaemias and lymphomas
    Annals of Oncology, vol. 18, no. 9, pp. 1569–1577, 2007
  27. Symptoms of anxiety and depression in patients with stable coronary heart disease: prognostic value and consideration of pathogenetic links
    European Journal of Cardiovascular Prevention & Rehabilitation, vol. 14, no. 4, pp. 547–554, 2007
  28. The functional genetic variant Arg324Gly of frizzled-related protein is associated with colorectal cancer risk
    Carcinogenesis, vol. 28, no. 9, pp. 1914–1917, 2007
  29. Genetic polymorphisms in TP53, nonsteroidal anti-inflammatory drugs and the risk of colorectal cancer: evidence for gene???environment interaction?
    Pharmacogenetics and Genomics, vol. 17, no. 8, pp. 639–645, 2007
  30. Body Mass Index and Premature Mortality in Physically Heavily Working Men???A Ten-Year Follow-Up of 20,000 Construction Workers
    Journal of Occupational and Environmental Medicine, vol. 49, no. 8, pp. 913–921, 2007
  31. Case-Control Study Supports Extension of Surveillance Interval After Colonoscopic Polypectomy to at Least 5 Yr
    The American Journal of Gastroenterology, vol. 102, no. 8, pp. 1739–1744, 2007
  32. Effects of practitioner education, practitioner payment and reimbursement of patients' drug costs on smoking cessation in primary care: a cluster randomised trial
    Tobacco Control, vol. 16, no. 1, pp. 15–21, 2007
  33. Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840 149 screening colonoscopies
    Gut, vol. 56, no. 11, pp. 1585–1589, 2007
  34. Potential for Colorectal Cancer Prevention of Sigmoidoscopy Versus Colonoscopy: Population-Based Case Control Study
    Cancer Epidemiology Biomarkers & Prevention, vol. 16, no. 3, pp. 494–499, 2007
  35. Genotype combinations of plasminogen activator inhibitor-1 and angiotensin-converting enzyme genes and risk for early onset of coronary heart disease
    European Journal of Cardiovascular Prevention & Rehabilitation, vol. 13, no. 3, pp. 449–456, 2006
  36. Death Receptor 4 Variants and Colorectal Cancer Risk
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 10, pp. 2002–2005, 2006
  37. Up-to-Date Estimates of Cancer Patient Survival Even with Common Latency in Cancer Registration
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 9, pp. 1727–1732, 2006
  38. Effect of NAT1 and NAT2 Genetic Polymorphisms on Colorectal Cancer Risk Associated with Exposure to Tobacco Smoke and Meat Consumption
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 1, pp. 99–107, 2006
  39. Prevalence of Chronic Atrophic Gastritis in Different Parts of the World
    Cancer Epidemiology Biomarkers & Prevention, vol. 15, no. 6, pp. 1083–1094, 2006
  40. Helicobacter pylori Infection and Colorectal Cancer Risk: A Meta-Analysis
    Helicobacter, vol. 11, no. 2, pp. 75–80, 2006
  41. The Mother as Source of Helicobacter pylori Infection
    Epidemiology, vol. 17, no. 3, pp. 332–334, 2006
  42. Higher long-term cancer survival rates in southeastern Netherlands using up-to-date period analysis
    Annals of Oncology, vol. 17, no. 4, pp. 709–712, 2006
  43. Up-to-date and Precise Estimates of Cancer Patient Survival: Model-based Period Analysis
    American Journal of Epidemiology, vol. 164, no. 7, pp. 689–696, 2006
  44. Calculating age-adjusted cancer survival estimates when age-specific data are sparse: an empirical evaluation of various methods
    British Journal of Cancer, vol. 94, no. 3, Article ID 6602976, 4 pages, 2006
  45. The impact of body weight on smoking cessation in German adults
    Preventive Medicine, vol. 42, no. 2, pp. 109–113, 2006
  46. Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum
    International Journal of Cancer, vol. 119, no. 3, pp. 695–701, 2006
  47. Cigarette smoking and colorectal cancer risk in Germany: A population-based case–control study
    International Journal of Cancer, vol. 119, no. 3, pp. 630–635, 2006
  48. Comparison of N-Terminal Pro-B-Natriuretic Peptide, C-Reactive Protein, and Creatinine Clearance for Prognosis in Patients With Known Coronary Heart Disease
    Archives of Internal Medicine, vol. 166, no. 22, pp. 2455–2460, 2006
  49. A population-based study of the impact of specific symptoms on quality of life in women with breast cancer 1 year after diagnosis
    Cancer, vol. 107, no. 10, pp. 2496–2503, 2006
  50. Role of cytomegalovirus sero-status in the development of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes
    International Journal of Cardiology, vol. 111, no. 1, pp. 98–103, 2006
  51. Restrictions in quality of life in colorectal cancer patients over three years after diagnosis: A population based study
    European Journal of Cancer, vol. 42, no. 12, pp. 1848–1857, 2006
  52. Clustering of Helicobacter pylori Infection in Couples: Differences Between High- and Low-Prevalence Population Groups
    Annals of Epidemiology, vol. 16, no. 7, pp. 516–520, 2006
  53. SULT1A1 genotype and susceptibility to colorectal cancer
    International Journal of Cancer, vol. 120, no. 1, pp. 201–206, 2006
  54. The course of high-sensitive C-reactive protein in correlation with pain and clinical function in patients with acute lumbosciatic pain and chronic low back pain – A 6 months prospective longitudinal study
    European Journal of Pain, vol. 10, no. 8, pp. 711–719, 2006
  55. The Underestimated Impact of Smoking and Smoking Cessation on the Risk of Secondary Cardiovascular Disease Events in Patients With Stable Coronary Heart Disease: Prospective Cohort Study
    Journal of the American College of Cardiology, vol. 47, no. 4, pp. 887–889, 2006
  56. ARLTS1 variants and risk of colorectal cancer
    Cancer Letters, vol. 244, no. 2, pp. 172–175, 2006
  57. The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study
    Journal of Clinical Epidemiology, vol. 59, no. 1, pp. 82–89, 2006
  58. Period estimates of cancer patient survival are more up-to-date than complete estimates even at comparable levels of precision
    Journal of Clinical Epidemiology, vol. 59, no. 6, pp. 570–575, 2006
  59. Lipoprotein-Associated Phospholipase A2 Predicts Future Cardiovascular Events in Patients With Coronary Heart Disease Independently of Traditional Risk Factors, Markers of Inflammation, Renal Function, and Hemodynamic Stress
    Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 7, pp. 1586–1593, 2006
  60. BMC Infectious Diseases, vol. 6, no. 1, p. 119, 2006
  61. Adiponectin and Leptin in Maternal Serum, Cord Blood, and Breast Milk
    Clinical Chemistry, vol. 52, no. 11, pp. 2095–2102, 2006
  62. BMC Health Services Research, vol. 6, no. 1, p. 70, 2006
  63. Tumor M2 Pyruvate Kinase as a Stool Marker for Colorectal Cancer: Stability at Room Temperature and Implications for Application in the Screening Setting
    Clinical Chemistry, vol. 52, no. 4, pp. 782–784, 2006
  64. BMC Cardiovascular Disorders, vol. 6, no. 1, p. 17, 2006
  65. BMC Family Practice, vol. 7, no. 1, p. 42, 2006
  66. Relationship of Adiponectin with Markers of Systemic Inflammation, Atherogenic Dyslipidemia, and Heart Failure in Patients with Coronary Heart Disease
    Clinical Chemistry, vol. 52, no. 5, pp. 853–859, 2006
  67. Do Older Adults Using NSAIDs Have a Reduced Risk of Colorectal Cancer?
    Drugs & Aging, vol. 23, no. 6, pp. 513–523, 2006
  68. Persistence of Restrictions in Quality of Life From the First to the Third Year After Diagnosis in Women With Breast Cancer
    Journal of Clinical Oncology, vol. 23, no. 22, pp. 4945–4953, 2005
  69. Long-Term Survival and Cure of Patients Diagnosed With Breast Cancer Before Age 50 Years
    Journal of Clinical Oncology, vol. 23, no. 7, pp. 1585–1585, 2005
  70. Helicobacter pylori???Specific Immune Response in Maternal Serum, Cord Blood, and Human Milk Among Mothers With and Without Current Helicobacter pylori Infection
    Pediatric Research, vol. 58, no. 5, pp. 897–902, 2005
  71. Does a negative screening colonoscopy ever need to be repeated?
    Gut, vol. 55, no. 8, pp. 1145–1150, 2005
  72. BMC Cardiovascular Disorders, vol. 5, no. 1, p. 10, 2005
  73. Genotype and Plasma Concentration of Cystatin C in Patients With Coronary Heart Disease and Risk for Secondary Cardiovascular Events
    Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 7, pp. 1470–1474, 2005
  74. Plasma Concentrations of Cystatin C in Patients with Coronary Heart Disease and Risk for Secondary Cardiovascular Events: More than Simply a Marker of Glomerular Filtration Rate
    Clinical Chemistry, vol. 51, no. 2, pp. 321–327, 2005
  75. Prognostic value of inflammatory markers alone and in combination with blood lipids in patients with stable coronary artery disease
    European Journal of Internal Medicine, vol. 16, no. 1, pp. 47–52, 2005
  76. Period analysis of cancer patient survival in datasets from which the month of diagnosis has been removed
    European Journal of Cancer, vol. 41, no. 3, pp. 438–444, 2005
  77. Association between Lp-PLA and coronary artery disease: Focus on its relationship with lipoproteins and markers of inflammation and hemostasis
    Atherosclerosis, 2005
  78. Relationship between Lifetime Alcohol Consumption and Infection
    Annals of Epidemiology, vol. 15, no. 8, pp. 607–613, 2005
  79. Role of infection in iron deficiency during pregnancy
    American Journal of Obstetrics and Gynecology, vol. 192, no. 2, pp. 548–553, 2005
  80. New stool tests for colorectal cancer screening: A systematic review focusing on performance characteristics and practicalness
    International Journal of Cancer, vol. 117, no. 2, pp. 169–176, 2005
  81. Prevalence and determinants of exocrine pancreatic insufficiency among older adults: Results of a population-based study
    Scandinavian Journal of Gastroenterology, vol. 40, no. 6, pp. 697–704, 2005
  82. Population-based monitoring of cancer patient survival in situations with imperfect completeness of cancer registration
    British Journal of Cancer, Article ID 6602323, 2005
  83. Cancer survival in Kampala, Uganda
    British Journal of Cancer, vol. 92, no. 9, Article ID 6602540, 4 pages, 2005
  84. Age adjustment of cancer survival rates: methods, point estimates and standard errors
    British Journal of Cancer, vol. 93, no. 3, Article ID 6602704, 3 pages, 2005
  85. Adiponectin, risk of coronary heart disease and correlations with cardiovascular risk markers
    European Heart Journal, vol. 26, no. 16, pp. 1640–1646, 2005
  86. Hospitalisations before and after nursing home admission: a retrospective cohort study from Germany
    Age and Ageing, vol. 34, no. 3, pp. 291–294, 2005
  87. Substantial Overestimation of Standard Errors of Relative Survival Rates of Cancer Patients
    American Journal of Epidemiology, vol. 161, no. 8, pp. 781–786, 2005
  88. Long-term survival of cancer patients in Germany achieved by the beginning of the third millenium
    Annals of Oncology, vol. 16, no. 6, pp. 981–986, 2005
  89. Reduction of clinically manifest colorectal cancer by endoscopic screening: empirical evaluation and comparison of screening at various ages
    European Journal of Cancer Prevention, vol. 14, no. 3, pp. 231–237, 2005
  90. Lack of training as a central barrier to the promotion of smoking cessation: a survey among general practitioners in Germany
    The European Journal of Public Health, vol. 15, no. 2, pp. 140–145, 2005
  91. Smoking, apolipoprotein???E genotype, and early onset of coronary heart disease
    European Journal of Cardiovascular Prevention & Rehabilitation, vol. 12, no. 3, pp. 268–270, 2005
  92. Major differences in prevalence of overweight according to nationality in preschool children living in Germany: determinants and public health implications
    Archives of Disease in Childhood, vol. 90, no. 4, pp. 359–363, 2005
  93. A Simulation Model for Colorectal Cancer Screening: Potential of Stool Tests with Various Performance Characteristics Compared with Screening Colonoscopy
    Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 2, pp. 422–428, 2005
  94. Further Enhanced Monitoring of Cancer Patient Survival by Stage-Adjusted Period Analysis
    Cancer Epidemiology Biomarkers & Prevention, vol. 14, no. 8, pp. 1917–1921, 2005
  95. Epidemiology of Helicobacter pylori Infection
    Helicobacter, vol. 9, no. s1, pp. 1–6, 2004
  96. Role of Lewis A and Lewis B Blood Group Antigens in Helicobacter pylori Infection
    Helicobacter, vol. 9, no. 4, pp. 324–329, 2004
  97. Severity and extent of osteoarthritis and low grade systemic inflammation as assessed by high sensitivity C reactive protein
    Annals of the Rheumatic Diseases, vol. 63, no. 2, pp. 200–205, 2004
  98. Helicobacter pylori and hepatitis A virus infections and the cardiovascular risk profile in patients with diabetes mellitus: results of a population-based study
    European Journal of Cardiovascular Prevention & Rehabilitation, vol. 11, no. 6, pp. 471–476, 2004
  99. Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und optimierten Therapie chronischer Erkrankungen in der älteren Bevölkerung (ESTHER-Studie)
    DMW - Deutsche Medizinische Wochenschrift, vol. 129, no. 49, pp. 2643–2647, 2004
  100. Is Helicobacter pylori Infection a Necessary Condition for Noncardia Gastric Cancer?
    American Journal of Epidemiology, vol. 159, no. 3, pp. 252–258, 2004
  101. Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001
    British Journal of Cancer, vol. 90, no. 7, Article ID 6601696, 6 pages, 2004
  102. and gastric cancer
    Gastroenterology, vol. 126, no. 7, p. 1927, 2004
  103. Cancer survival in a southern African urban population
    International Journal of Cancer, vol. 112, no. 5, pp. 860–864, 2004
  104. Prevalence and determinants of antibiotic resistance in faecalEscherichia coli among unselected patients attending general practitioners in Southwest Germany
    Pharmacoepidemiology and Drug Safety, vol. 13, no. 5, pp. 303–308, 2004
  105. Epidemiology in aging research
    Experimental Gerontology, vol. 39, no. 5, pp. 679–686, 2004
  106. The German Center for Research on Aging at the University of Heidelberg: an interdisciplinary approach
    Experimental Gerontology, vol. 39, no. 1, pp. 3–9, 2004
  107. Age-specific detriments to quality of life among breast cancer patients one year after diagnosis
    European Journal of Cancer, vol. 40, no. 5, pp. 673–680, 2004
  108. Modification of SAS macros for a more efficient analysis of relative survival rates
    European Journal of Cancer, vol. 40, no. 5, pp. 778–779, 2004
  109. Drug interactions in primary care: Impact of a new algorithm on risk determination*1
    Clinical Pharmacology & Therapeutics, vol. 76, no. 1, pp. 85–96, 2004
  110. A computer program to estimate power and relative efficiency to assess multiplicative interactions in flexibly matched case-control studies
    Computer Methods and Programs in Biomedicine, vol. 74, no. 3, pp. 261–265, 2004
  111. Period analysis for 'up-to-date' cancer survival data theory, empirical evaluation, computational realisation and applications
    European Journal of Cancer, vol. 40, no. 3, pp. 326–335, 2004
  112. Evidence of a rapid decrease in prevalence of Helicobacter pylori infection in children of a high risk group living in Germany
    European Journal of Pediatrics, vol. 163, no. 6, pp. 339–340, 2004
  113. Age, alcohol consumption, and all-cause mortality*1
    Annals of Epidemiology, vol. 14, no. 10, pp. 750–753, 2004
  114. Recent increase in cancer survival according to age: higher survival in all age groups, but widening age gradient
    Cancer Causes and Control, vol. 15, no. 9, pp. 903–910, 2004
  115. Short-term benefit of smoking cessation in patients with coronary heart disease: estimates based on self-reported smoking data and serum cotinine measurements
    European Heart Journal, vol. 25, no. 23, pp. 2101–2108, 2004
  116. An alternative approach to age adjustment of cancer survival rates
    European Journal of Cancer, vol. 40, no. 15, pp. 2317–