Michel Tibayrenc

Michel Tibayrenc was born in 1947. He received his M.D. degree in 1975 and his Ph.D. degree in 1986, University of Paris. Specialized diploma: Sport Medicine (1974), Tropical Medicine (1974), Parasitology (1976), Leprology (1977), and Medical Entomology (1978). From 1970 to 1974, he was a general medical practitioner. Since 1977, he has been a researcher at the Institut de Recherche pour le développement (IRD), the French National Agency for Research in Developing Countries. He spent 1 year in French Guiana, 5 years in Bolivia, total of 4 years in the USA (UC Davis, UC Irvine, Centers for Disease Control). Since the 1st of October 2005, he is a IRD representative in Bangkok, Thailand. Grade: Directeur de Recherche de Classe exceptionnelle (the highest grade in the French research system). He is the Initiator and main Organizer of the International Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (MEEGID) Congress (8th session held in Bangkok, November 2006). He is also the Initiator and Editor-in-Chief of the journal Infection, Genetics and Evolution (Elsevier), and the Initiator of the European Centre for Infectious Diseases project, a European equivalent to the US National Center for Infectious Diseases (one of the main branches of the CDC), presently developed into a proposal for a “world CDC Belt” composed of 5 major centers around the world.

Biography Updated on 18 March 2007

Articles in Scholarly Journals [Incomplete List]

  1. Infection, Genetics & Evolution: a journal with a high impact but no Impact Factor (as yet)
    Infection, Genetics and Evolution, vol. 7, no. 2, pp. 145–146, 2007
  2. From MEEGID VII in Valencia to MEEGID VIII in Bangkok: 10th anniversary of the MEEGID congress
    Infection, Genetics and Evolution, vol. 6, no. 2, pp. 131–132, 2006
  3. The species concept in parasites and other pathogens: a pragmatic approach?
    Trends in Parasitology, vol. 22, no. 2, pp. 66–70, 2006
  4. Phylogenetic analysis of the glucose-6-phosphate isomerase gene in Trypanosoma cruzi?
    Experimental Parasitology, vol. 113, no. 1, pp. 1–7, 2006
  5. Trypanosoma cruzi: Sequence analysis of the variable region of kinetoplast minicircles
    Experimental Parasitology, vol. 114, no. 4, pp. 279–288, 2006
  6. Population structure of malaria parasites: The driving epidemiological forces
    Acta Tropica, 2005
  7. Which species concept for pathogenic bacteria?An E-Debate
    Infection, Genetics and Evolution, vol. 5, no. 4, pp. 375–387, 2005
  8. A hard lesson for Europeans: the ASEAN CDC
    Trends in Microbiology, vol. 13, no. 6, pp. 266–268, 2005
  9. Bridging the gap between molecular epidemiologists and evolutionists
    Trends in Microbiology, vol. 13, no. 12, pp. 575–580, 2005
  10. Differential Gene Expression in Benznidazole-Resistant Trypanosoma cruzi Parasites
    Antimicrobial Agents and Chemotherapy, vol. 49, no. 7, pp. 2701–2709, 2005
  11. A molecular biology approach to tuberculosis
    Proceedings of the National Academy of Sciences, vol. 101, no. 14, pp. 4721–4722, 2004
  12. Genetic Diversity and Population Structure of Mycobacterium tuberculosis in Casablanca, a Moroccan City with High Incidence of Tuberculosis
    Journal of Clinical Microbiology, vol. 42, no. 1, pp. 461–466, 2004
  13. Predominant clonal evolution leads to a close parity between gene expression profiles and subspecific phylogeny in Trypanosoma cruzi
    Molecular and Biochemical Parasitology, vol. 137, no. 1, pp. 133–141, 2004
  14. Lack of correlation between in vitro susceptibility to Benznidazole and phylogenetic diversity of , the agent of Chagas disease
    Experimental Parasitology, vol. 108, no. 1-2, pp. 24–31, 2004
  15. Trypanosoma cruzi: long-term sub-cultures in two different culture media do not confirm the existence of highly versatile multilocus genotypes
    International Journal for Parasitology, vol. 34, no. 7, pp. 779–784, 2004
  16. Evolution and immunology of infectious diseases: what's new? An E-debate
    Infection, Genetics and Evolution, vol. 4, no. 1, pp. 69–75, 2004
  17. 2004: MEEGID VII and the year of Infection, Genetics and Evolution
    Infection, Genetics and Evolution, vol. 4, no. 1, pp. 3–4, 2004
  18. The European Commission pocket CDC: !
    The Lancet Infectious Diseases, vol. 4, no. 1, pp. 12–13, 2004
  19. An isoenzyme survey of Trypanosoma brucei s.l. from the Central African subregion: population structure, taxonomic and epidemiological considerations
    Parasitology, vol. 128, no. 6, pp. 645–653, 2004
  20. Evidence for genetic exchange and hybridization in Trypanosoma cruzi based on nucleotide sequences and molecular karyotype
    Infection, Genetics and Evolution, vol. 2, no. 3, pp. 173–183, 2003
  21. Infectious diseases and the Human Genome Diversity Project
    Infection, Genetics and Evolution, vol. 2, no. 3, pp. 165–166, 2003
  22. MEEGID VI: Sixth International Meeting on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases, Paris, 23–27 July 2002
    Infection, Genetics and Evolution, vol. 2, no. 4, pp. 231–234, 2003
  23. To the heroes of Columbia, departed for science and discovery Manned space flights do better than robots
    Infection, Genetics and Evolution, vol. 3, no. 1, pp. 1–2, 2003
  24. Corrigendum to “Phylogenetic diversity of bat trypanosomes of subgenus Schizotrypanum based on multilocus enzyme electrophoresis, random amplified polymorphic DNA, and cytrochrome b nucleotide sequence analyses” [Inf. Gen. Evol. 2 (2003) 201–208]
    Infection, Genetics and Evolution, vol. 3, no. 2, p. 151, 2003
  25. Multilocus enzyme electrophoresis analysis of Trypanosoma cruzi isolates from a geographically restricted endemic area for Chagas' disease in Argentina
    International Journal for Parasitology, vol. 33, no. 10, pp. 997–1003, 2003
  26. Chemotherapy with Benznidazole and Itraconazole for Mice Infected with Different Trypanosoma cruzi Clonal Genotypes
    Antimicrobial Agents and Chemotherapy, vol. 47, no. 1, pp. 223–230, 2003
  27. Kinetoplastid Biology and Disease, vol. 2, no. 1, p. 12, 2003
  28. Impact of number of isoenzyme loci on the robustness of intraspecific phylogenies using multilocus enzyme electrophoresis: consequences for typing of Trypanosoma cruzi
    Parasitology, vol. 127, no. 3, pp. 273–281, 2003
  29. Linkage disequilibrium between minisatellite loci supports clonal evolution of Mycobacterium tuberculosis in a high tuberculosis incidence area
    Molecular Microbiology, vol. 47, no. 2, pp. 529–538, 2003
  30. Microsatellite analysis of Toxoplasma gondii shows considerable polymorphism structured into two main clonal groups
    International Journal for Parasitology, vol. 32, no. 1, pp. 27–38, 2002
  31. isoenzyme variability in Ecuador: first observation of zymodeme III genotypes in chronic chagasic patients
    Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 96, no. 4, pp. 378–382, 2002
  32. The clonal theory of parasitic protozoa: 12 years on
    Trends in Parasitology, vol. 18, no. 9, pp. 405–410, 2002
  33. Chromosomal size variation in Trypanosoma cruzi is mainly progressive and is evolutionarily informative
    Parasitology, vol. 124, no. 3, pp. 277–286, 2002
  34. Molecular epidemiology of Mycobacterium tuberculosis and its relevance to the surveillance and control of TB: an e-debate
    Infection, Genetics and Evolution, vol. 2, no. 2, pp. 153–158, 2002
  35. 2002 Neodarwinism and infectious diseases transmission: An e-debate
    Infection, Genetics and Evolution, vol. 1, no. 3, pp. 249–253, 2002
  36. The European Centre for Infectious Diseases: An adequate response to the challenges of bioterrorism and major natural infectious threats
    Infection, Genetics and Evolution, vol. 1, no. 3, pp. 179–181, 2002
  37. Basic vs. applied research, field vs. bench work: the never-ending dialogues of the deaf
    Infection, Genetics and Evolution, vol. 1, no. 4, pp. 263–264, 2002
  38. Basic research: what is it good for AIDS epidemiology and control? An e-debate
    Infection, Genetics and Evolution, vol. 1, no. 4, pp. 313–320, 2002
  39. Is integrated genetic epidemiology on the way? The MEEGID VI Congress
    Infection, Genetics and Evolution, vol. 2, no. 1, p. 1, 2002
  40. Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice
    Experimental Parasitology, vol. 100, no. 3, pp. 161–172, 2002
  41. Trypanosoma cruzi: isoenzyme analysis suggests the presence of an active Chagas sylvatic cycle of recent origin in Paraná State, Brazil
    Experimental Parasitology, vol. 100, no. 2, pp. 81–86, 2002
  42. Trypanosoma cruzi: presence of the two major phylogenetic lineages and of several lesser discrete typing units (DTUs) in Chile and Paraguay
    Acta Tropica, vol. 78, no. 2, pp. 127–137, 2001
  43. Trypanosoma cruzi: A Considerable Phylogenetic Divergence Indicates That the Agent of Chagas Disease Is Indigenous to the Native Fauna of the United States
    Experimental Parasitology, vol. 99, no. 2, pp. 73–79, 2001
  44. Infectious diseases and the golden age of phylogenetics: An E-debate
    Infection, Genetics and Evolution, vol. 1, no. 1, pp. 69–74, 2001
  45. The population structure of Neisseria meningitidis serogroup A fits the predictions for clonality
    Infection, Genetics and Evolution, vol. 1, no. 2, pp. 117–122, 2001
  46. The Golden Age of Genetics and the Dark Age of Infectious Diseases
    Infection, Genetics and Evolution, vol. 1, no. 1, pp. 1–2, 2001
  47. Population genetics and population biology: what did they bring to the epidemiology of transmissible diseases? An e-debate
    Infection, Genetics and Evolution, vol. 1, no. 2, pp. 161–166, 2001
  48. The Golden Age of Genetics?
    Infection, Genetics and Evolution, vol. 1, no. 2, pp. 83–84, 2001
  49. Genetic heterogeneity and phylogenetic status of Leishmania (Leishmania) infantum zymodeme MON-1: epidemiological implications
    Parasitology, vol. 123, no. 5, pp. 425–432, 2001
  50. Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages
    International Journal for Parasitology, vol. 31, no. 11, pp. 1218–1226, 2001
  51. High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology
    Proceedings of the National Academy of Sciences, vol. 98, no. 4, pp. 1901–1906, 2001
  52. Evidence for clonal propagation in natural isolates of Plasmodium falciparum from Venezuela
    Proceedings of the National Academy of Sciences, vol. 98, no. 12, pp. 6725–6729, 2001
  53. Genetic Diversity of Pseudomonas aeruginosa Strains Isolated from Ventilated Patients with Nosocomial Pneumonia, Cancer Patients with Bacteremia, and Environmental Water
    Infection and Immunity, vol. 69, no. 1, pp. 584–588, 2001
  54. Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach
    Parasitology, vol. 120, no. 5, pp. 513–526, 2000
  55. Prevalence of Virulence Genes and Clonality in Escherichia coli Strains That Cause Bacteremia in Cancer Patients
    Infection and Immunity, vol. 68, no. 7, pp. 3983–3989, 2000
  56. Is Leishmania (Viannia) peruviana a Distinct Species? A MLEE/RAPD Evolutionary Genetics Answer
    The Journal of Eukaryotic Microbiology, vol. 47, no. 3, pp. 197–207, 2000
  57. Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis
    International Journal for Parasitology, vol. 30, no. 1, pp. 35–44, 2000
  58. Identification of six Trypanosoma cruzi lineages by sequence-characterised amplified region markers
    Molecular and Biochemical Parasitology, vol. 111, no. 1, pp. 95–105, 2000
  59. Infectivity of Clonal Genotype Infections in Acute and Chronic Phases in Mice
    Experimental Parasitology, vol. 96, no. 2, pp. 61–66, 2000
  60. Experimental Trypanosoma cruzi biclonal infection in Triatoma infestans: detection of distinct clonal genotypes using kinetoplast DNA probes
    International Journal for Parasitology, vol. 30, no. 7, pp. 843–848, 2000
  61. Plasmodium falciparum: Population Genetic Analysis by Multilocus Enzyme Electrophoresis and Other Molecular Markers, , ,
    Experimental Parasitology, vol. 92, no. 4, pp. 232–238, 1999
  62. Evolutionary genetics of Trypanosoma and Leishmania
    Microbes and Infection, vol. 1, no. 6, pp. 465–472, 1999
  63. European centre for infectious disease
    The Lancet, vol. 353, no. 9149, pp. 329–329, 1999
  64. Molecular epidemiology and evolutionary genetics of Leishmania parasites
    International Journal for Parasitology, vol. 29, no. 8, pp. 1137–1147, 1999
  65. Genetic epidemiology of parasitic protozoa and other infectious agents: the need for an integrated approach
    International Journal for Parasitology, vol. 28, no. 1, pp. 85–104, 1998
  66. A phylogenetic analysis of the Trypanosoma cruzi genome project CL Brener reference strain by multilocus enzyme electrophoresis and multiprimer random amplified polymorphic DNA fingerprinting
    Molecular and Biochemical Parasitology, vol. 92, no. 2, pp. 253–263, 1998
  67. Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen
    Molecular and Biochemical Parasitology, vol. 92, no. 2, pp. 241–252, 1998
  68. Beyond Strain Typing and Molecular Epidemiology: Integrated Genetic Epidemiology of Infectious Diseases
    Parasitology Today, vol. 14, no. 8, pp. 323–329, 1998
  69. Trypanosoma cruzi:Impact of Clonal Evolution of the Parasite on Its Biological and Medical Properties
    Experimental Parasitology, vol. 89, no. 1, pp. 30–39, 1998
  70. Different Behavior of TwoTrypanosoma cruziMajor Clones: Transmission and Circulation in Young Bolivian Patients, ,
    Experimental Parasitology, vol. 89, no. 3, pp. 285–295, 1998
  71. : Compared Vectorial Transmissibility of Three Major Clonal Genotypes by
    Experimental Parasitology, vol. 90, no. 1, pp. 20–25, 1998
  72. Compared vectorial transmissibility of pure and mixed clonal genotypes of Trypanosoma cruzi in Triatoma infestans
    Parasitology Research, vol. 84, no. 5, pp. 348–353, 1998
  73. Nature, vol. 396, no. 6707, pp. 108–108, 1998
  74. Comparison of chromosome and isoenzyme polymorphism in geographical populations of Leishmania (Viannia) peruviana
    Parasitology, vol. 117, no. 6, pp. 547–554, 1998
  75. Population structure of Andean Triatoma infestans: allozyme frequencies and their epidemiological relevance
    Medical and Veterinary Entomology, vol. 12, no. 1, pp. 20–29, 1998
  76. Evidence for Hybridization by Multilocus Enzyme Electrophoresis and Random Amplified Polymorphic DNA Between Leishmania braziliensis and Leishmania panamensis/guyanensis in Ecuador
    The Journal of Eukaryotic Microbiology, vol. 44, no. 5, pp. 408–411, 1997
  77. Aids, vol. 11, no. 5, pp. 569–573, 1997
  78. Population Structure of Trypanosoma brucei s. l. in Cote D'Ivoire Assayed by Multilocus Enzyme Electrophoresis: Epidemiological and Taxonomical Considerations
    The Journal of Parasitology, vol. 83, no. 1, p. 19, 1997
  79. Trypanosoma cruzi: Evaluation of a RAPD Synapomorphic Fragment as a Species-Specific DNA Probe
    The Journal of Parasitology, vol. 83, no. 1, p. 52, 1997
  80. Are natural populations subdivided?
    Trends in Microbiology, vol. 5, no. 7, pp. 253–254, 1997
  81. Impact of clonal evolution on the biological diversity of Trypanosoma cruzi
    Parasitology, vol. 114, no. 3, pp. 213–218, 1997
  82. TOWARDS A UNIFIED EVOLUTIONARY GENETICS OF MICROORGANISMS
    Annual Review of Microbiology, vol. 50, no. 1, pp. 401–429, 1996
  83. Enzymatic variability and phylogenetic relatedness among Triatoma infestans, T. platensis, T. delpontei and T. rubrovaria
    Heredity, vol. 77, no. 1, Article ID 6880070, 7 pages, 1996
  84. Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru
    Acta Tropica, vol. 59, no. 4, pp. 293–307, 1995
  85. An Isoenzyme Survey of Trypanosoma cruzi Genetic Variability in Sylvatic Cycles from French Guiana
    Experimental Parasitology, vol. 81, no. 1, pp. 20–28, 1995
  86. Genetic diversity and population structure of Trypanosoma brucei: clonality versus sexuality
    Molecular and Biochemical Parasitology, vol. 72, no. 1-2, pp. 89–101, 1995
  87. Antigenic diversity and the transmission dynamics of Plasmodium falciparum: The clonality/sexuality debate revisited
    Parasitology Today, vol. 10, no. 12, pp. 456–457, 1994
  88. Clonality in Leishmania
    Parasitology Today, vol. 9, no. 2, p. 58, 1993
  89. Entamoeba, giardia and toxoplasma: clones or cryptic species?
    Parasitology Today, vol. 9, no. 3, pp. 102–105, 1993
  90. Genetic Charcterization of Six Parasitic Protozoa: Parity Between Random- Primer DNA Typing and Multilocus Enzyme Electrophoresis
    Proceedings of the National Academy of Sciences, vol. 90, no. 4, pp. 1335–1339, 1993
  91. THE DECLINING POLITICAL SIGNIFICANCE OF SOCIAL CLASS
    International Sociology, vol. 8, no. 3, pp. 293–316, 1993
  92. Leishmania: Sex, karyotypes and population genetics
    Parasitology Today, vol. 8, no. 9, pp. 305–306, 1992
  93. Clonal defence
    Nature, vol. 350, no. 6317, Article ID 350385b0, 1 pages, 1991
  94. Linkage Disequilibrium in Natural Populations of Trypanosoma cruzi (Flagellate), the Agent of Chagas' Disease
    The Journal of Eukaryotic Microbiology, vol. 35, no. 1, pp. 81–85, 1988
  95. Trypanosoma cruzi populations: More clonal than sexual
    Parasitology Today, vol. 3, no. 6, pp. 189–190, 1987
  96. Additional data on Trypanosoma cruzi isozymic strains encountered in Bolivian domestic transmission cycles
    Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 80, no. 3, pp. 442–447, 1986
  97. Natural Populations of Trypanosoma cruzi, the Agent of Chagas Disease, Have a Complex Multiclonal Structure
    Proceedings of the National Academy of Sciences, vol. 83, no. 1, pp. 115–119, 1986
  98. Agent of Chagas' disease from Honduran vector capable of developing in California insects: Implications for cardiologists
    American Heart Journal, vol. 110, no. 3, pp. 605–608, 1985
  99. The microdistribution of isoenzymic strains of Trypanosoma cruzi in southern Bolivia; new isoenzyme profiles and further arguments against Mendelian sexuality
    Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 78, no. 4, pp. 519–525, 1984
  100. The presence in Bolivia of two distinct zymodemes of Trypanosoma cruzi, circulating sympatrically in a domestic transmission cycle
    Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 77, no. 1, pp. 73–75, 1983
  101. A genetic comparison between Brazilian and Bolivian zymodemes of Trypanosoma cruzi
    Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 77, no. 1, pp. 76–83, 1983