Rainer de Martin
Rainer de Martin was born in 1958 in Vienna, Austria. He studied pharmacy at the University of Vienna and received his Ph.D. degree in 1985. After the first 2-year postdoctoral training at the Novartis (at that time Sandoz) Research Institute in Vienna, where he turned to molecular biology and which resulted in the cloning of human TGFß2, he moved to Novartis in Basel, Switzerland, to continue this work. In 1989, he joined Lennart Philipson's Group at the European Molecular Biology Laboratory (Heidelberg) to work on growth arrest-specific genes. Martin returned to Vienna in 1991, where he joined the group of F.H. Bach as a Head of laboratory to work in a Novartis-funded group dedicated to genetically engineer vascularized pig organs to serve as donors for xenotransplantation. These studies, which among other findings lead to the identification of the NF-kB/IkBa negative feedback loop, have spurred his ongoing interest in transcriptional regulation and signal transduction in the field of vascular biology in general and in inflammation in particular. Moreover, these interests were then focused on the human system after joining the Medical University of Vienna in 1996, where two years later he was appointed as a Professor at the Department of Vascular Biology and Thrombosis Research. Current core interests of the lab are the molecular basis of the inflammatory response, including the signaling pathways, transcriptional regulation with particular emphasis on the role of NF-kB, the resolution of inflammation, and the identification and functional characterization of novel genes in this context.
Biography Updated on 2 May 2011