After a MSc. in structural biology in France, A. Echalier joined the university of Warwick to do her PhD on bacterial cytochrome c peroxidases. She structurally characterised them in different redox states to gain insight into their regulation. Moving in 2004 to the university of Oxford for a post-doctoral training, she worked on protein-kinases at the Laboratory of Molecular Biophysics headed by Professor Dame L. Johnson and then Professor M. Noble. During this time in Oxford, she studied the structure, function and inhibition of cell cycle cyclin-dependent kinases, as well as malarial kinases. In 2009 A. Echalier was appointed on a lectureship position joined between the university of Montpellier and the CNRS where she is pursuing her interest in cell cycle regulation and developing a research program on protein degradation. She is using X-ray crystallography, biochemistry, biophysical and computational approaches to characterise protein interactions implicated in cell signalling.
Biography Updated on 3 November 2013