Jürgen Wittmann works as a group leader at the Division of Molecular Immunology at the University of Erlangen-Nürnberg, Erlangen, Germany. He did his Ph.D. training under Dr. Hans-Martin Jäck and received his Ph.D. degree in molecular medicine from the University of Erlangen-Nürnberg in 2004. Wittmann also obtained his M.S. degree in biology in 2000. His overall research activities concentrate on posttranscriptional mechanisms of gene expression with an emphasis on various aspects of RNA biology in the immune system. In particular, the focus is on the impact of small non-protein-coding microRNAs on murine and human B cell development in health and disease. The second main project investigates the factors and mechanism by which aberrant mRNAs, so-called nonsense mRNAs, are detected and degraded and whether abnormal regulation of the nonsense-mediated mRNA decay (NMD) pathway contributes to diseases. Common to both projects is an interdisciplinary approach combining immunology, biochemistry, and bioinformatics together with molecular and cellular biology.
Biography Updated on 2 January 2013