Michael R. Moore
Michael R. Moore is the Director of the National Research Centre for Environmental Toxicology (EnTox). He received B.S. degree (with honors) in biochemistry, in 1967; the Ph.D. degree in medicine, in 1971; and the D.S. degree in biochemistry, in 1987, all from University of Glasgow. Michael is a registered toxicologist (Eurotox & Institute of Biology, UK) and Member of the Australasian College of Toxicology and Risk Assessment (ACTRA). He is a Professor in Medicine at the University of Queensland and Adjunct Professor in Griffith University, University of the Sunshine Coast, Queensland University of Technology. He is also a codirector of the Australian Centres for Human Health Risk Assessment. He has trained in Clinical Pharmacology in the Royal Postgraduate Medical School in London. He previously held senior appointments at the University of Glasgow, Glasgow Caledonian University, and Monklands and Bellshill Hospitals NHS Trust. As an international expert in toxicology of water pollutants relevant to public health, his areas of expertise include the toxicology of metals, air toxics, risk assessment, alcoholism, cyanobacterial toxins, and disorders of porphyrin metabolism. He is a Member of wide range of committees and advisory bodies on public health issues including the Australian Drug Evaluation Committee, the Australian Pesticides and Veterinary Medicines Authority and the National Drugs and Poisons Schedules Committee. He chaired the NHMRC Drinking water treatment chemicals working party and the Working Group on Air Quality in Tunnels and was a member in National Cyanobacterial Toxin Guidelines Working Group and the NHMRC Working party on Toxicology and Risk Assessment. He is a Prolific producer of research outputs with over 500 referred publications and numerous books and book chapters to date.
Biography Updated on 14 January 2008
Personal Home Page
http://www.entox.uq.edu.au/index.html?page=62194
Articles in Scholarly Journals [Incomplete List]
- Urinary arsenic and porphyrin profile in C57BL/6J mice chronically exposed to monomethylarsonous acid (MMAIII) for two years
Toxicology and Applied Pharmacology, vol. 224, no. 1, pp. 89–97, 2007 - Location and Vitamin D synthesis: Is the hypothesis validated by geophysical data?
Journal of Photochemistry and Photobiology B: Biology, vol. 86, no. 3, pp. 234–239, 2007 - Urinary arsenic methylation and porphyrin profile of C57Bl/6J mice chronically exposed to sodium arsenate
Science of The Total Environment, vol. 379, no. 2-3, pp. 235–243, 2007 - Urinary excretion of cadmium among Torres Strait Islanders (Australia) at risk of elevated dietary exposure through traditional foods
Journal of Exposure Science and Environmental Epidemiology, vol. 17, no. 4, Article ID 7500520, 5 pages, 2007 - Exploring potential dietary contributions including traditional seafood and other determinants of urinary cadmium levels among indigenous women of a Torres Strait Island (Australia)
Journal of Exposure Science and Environmental Epidemiology, vol. 17, no. 3, Article ID 7500547, 8 pages, 2007 - Toxicology in Australia: A Key Component of Environmental Health
Journal of Toxicology and Environmental Health, Part A, vol. 70, no. 19, pp. 1578–1583, 2007 - Public Health Risks from Heavy Metals and Metalloids Present in Traditional Chinese Medicines
Journal of Toxicology and Environmental Health, Part A, vol. 70, no. 19, pp. 1694–1699, 2007 - Regulation of CYP2A5 Gene by the Transcription Factor Nuclear Factor (Erythroid-Derived 2)-Like 2
Drug Metabolism and Disposition, vol. 35, no. 5, pp. 787–794, 2007 - Anxiety, post-traumatic stress disorder and depression in Korean War veterans 50 years after the war
The British Journal of Psychiatry, vol. 190, no. 6, pp. 475–483, 2007 - Kidney Dysfunction and Hypertension: Role for Cadmium, P450 and Heme Oxygenases?
The Tohoku Journal of Experimental Medicine, vol. 208, no. 3, pp. 179–202, 2006 - Endocrine-disrupting compounds: A review of their challenge to sustainable and safe water supply and water reuse
Environmental Toxicology, vol. 21, no. 2, pp. 181–191, 2006 - Urinary porphyrins as biomarkers for arsenic exposure among susceptible populations in Guizhou province, China
Toxicology and Applied Pharmacology, vol. 206, no. 2, pp. 176–184, 2005 - Cadmium-induced nephropathy in the development of high blood pressure
Toxicology Letters, vol. 157, no. 1, pp. 57–68, 2005 - Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
Toxicology Letters, vol. 159, no. 2, pp. 182–191, 2005 - Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5
Biochemical Pharmacology, vol. 70, no. 10, pp. 1527–1535, 2005 - Effects of cigarette smoking and exposure to cadmium and lead on phenotypic variability of hepatic CYP2A6 and renal function biomarkers in men
Toxicology, vol. 204, no. 2-3, pp. 161–173, 2004 - Influence of body iron store status and cigarette smoking on cadmium body burden of healthy Thai women and men
Toxicology Letters, vol. 148, no. 3, pp. 177–185, 2004 - A commentary on the impacts of metals and metalloids in the environment upon the metabolism of drugs and chemicals
Toxicology Letters, vol. 148, no. 3, pp. 153–158, 2004 - Effects of chronic exposure to low-level cadmium on renal tubular function and CYP2A6-mediated coumarin metabolism in healthy human subjects
Toxicology Letters, vol. 148, no. 3, pp. 187–197, 2004 - Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2
Toxicology Letters, vol. 148, no. 3, pp. 199–210, 2004 - Evidence for Concurrent Effects of Exposure to Environmental Cadmium and Lead on Hepatic CYP2A6 Phenotype and Renal Function Biomarkers in Non-smokers
Environmental Health Perspectives, 2004 - A global perspective on cadmium pollution and toxicity in non-occupationally exposed population
Toxicology Letters, vol. 137, no. 1-2, pp. 65–83, 2003 - Potential for early involvement of CYP isoforms in aspects of human cadmium toxicity
Toxicology Letters, vol. 137, no. 1-2, pp. 85–93, 2003 - Special issue on environmental toxicology of metals and metalloids
Toxicology Letters, vol. 137, no. 1-2, p. 1, 2003 - Associations between human liver and kidney cadmium content and immunochemically detected CYP4A11 apoprotein
Biochemical Pharmacology, vol. 63, no. 4, pp. 693–696, 2002 - Trace organic compounds in the marine environment
Marine Pollution Bulletin, vol. 45, no. 1-12, pp. 62–68, 2002 - Pharmacogenetics, vol. 12, no. 3, pp. 241–249, 2002
- A review of animal models for the study of arsenic carcinogenesis
Toxicology Letters, vol. 133, no. 1, pp. 17–31, 2002 - HPLC measurement of harderoporphyrin in the harderian glands of rodents as a biomarker for sub-lethal or chronic arsenic exposure
Toxicology Letters, vol. 133, no. 1, pp. 93–101, 2002 - Relationships between non-occupational cadmium exposure and expression of nine cytochrome P450 forms in human liver and kidney cortex samples
Biochemical Pharmacology, vol. 62, no. 6, pp. 713–721, 2001 - A sensitive and specific assay for glutathione with potential application to glutathione disulphide, using high-performance liquid chromatography–tandem mass spectrometry
Journal of Chromatography B: Biomedical Sciences and Applications, vol. 762, no. 1, pp. 17–23, 2001 - Distribution of14C cylindrospermopsinin vivo in the mouse
Environmental Toxicology, vol. 16, no. 6, pp. 498–505, 2001 - Extraction and purification of the zwitterions cylindrospermopsin and deoxycylindrospermopsin fromCylindrospermopsis raciborskii
Environmental Toxicology, vol. 16, no. 5, pp. 391–396, 2001 - Evidence for a Synergistic Interaction between Cadmium and Endotoxin Toxicity and for Nitric Oxide and Cadmium Displacement of Metals in the Kidney
Nitric Oxide, vol. 4, no. 4, pp. 431–440, 2000 - Public health implications of new guidelines for lead in drinking water: a case study in an area with historically high water lead levels
Food and Chemical Toxicology, vol. 38, pp. S73–S79, 2000 - Therapeutic Drug Monitoring, vol. 22, no. 1, pp. 58–60, 2000
- Therapeutic Drug Monitoring, vol. 22, no. 1, pp. 89–92, 2000
- The oral toxicity for mice of the tropical cyanobacteriumCylindrospermopsis raciborskii (Woloszynska)
Environmental Toxicology, vol. 14, no. 1, pp. 135–142, 1999 - Use of HPLC-MS/MS to monitor cylindrospermopsin, a blue-green algal toxin, for public health purposes
Environmental Toxicology, vol. 14, no. 1, pp. 151–154, 1999 - Stability of cylindrospermopsin, the toxin from the cyanobacterium,Cylindrospermopsis raciborskii: Effect of pH, temperature, and sunlight on decomposition
Environmental Toxicology, vol. 14, no. 1, pp. 155–161, 1999 - Deoxycylindrospermopsin, an analog of cylindrospermopsin fromCylindrospermopsis raciborskii
Environmental Toxicology, vol. 14, no. 1, pp. 163–165, 1999 - Blooms of the cylindrospermopsin containing cyanobacterium,Aphanizomenon ovalisporum (Forti), in newly constructed lakes, Queensland, Australia
Environmental Toxicology, vol. 14, no. 1, pp. 167–177, 1999 - Bracken Fern Carcinogenesis: Multiple Intravenous Doses of Activated Ptaquiloside Induce DNA Adducts, Monocytosis, Increased TNFa Levels, and Mammary Gland Carcinoma in Rats
Biochemical and Biophysical Research Communications, vol. 244, no. 1, pp. 192–197, 1998 - H-rasActivation Is an Early Event in the Ptaquiloside-Induced Carcinogenesis: Comparison of Acute and Chronic Toxicity in Rats
Biochemical and Biophysical Research Communications, vol. 250, no. 2, pp. 491–497, 1998 - H-rasActivation Is an Early Event in the Ptaquiloside-Induced Carcinogenesis: Comparison of Acute and Chronic Toxicity in Rats Volume 250, Number 2 (1998), pages 491–497:
Biochemical and Biophysical Research Communications, vol. 251, no. 2, p. 668, 1998 - Acute intermittent porphyria: alternative splicing of hydroxymethylbilane synthase mRNA excludes exons 3 and 12
Molecular and Cellular Probes, vol. 12, no. 2, pp. 63–70, 1998 - The Biochemistry of Heme Synthesis in Porphyria and in the Porphyrinurias
Clinics in Dermatology, vol. 16, no. 2, pp. 203–223, 1998 - Identification of Two Novel Mutations in the Hydroxymethylbilane Synthase Gene in Three Patients from Two Unrelated Families with Acute Intermittent Porphyria
Human Heredity, vol. 48, no. 1, pp. 24–29, 1998 - Therapeutic Drug Monitoring, vol. 20, no. 5, pp. 502–509, 1998
- Speciation of arsenic metabolites in the urine of occupational workers and experimental rats using an optimised hydride cold-trapping method†
The Analyst, vol. 123, no. 5, pp. 929–933, 1998 - Speciation and absolute bioavailability: risk assessment of arsenic-contaminated sites in a residential suburb in Canberra†
The Analyst, vol. 123, no. 5, pp. 889–892, 1998 - Acute intermittent porphyria: thein vitroexpression of mutant hydroxymethylbilane synthase
Molecular and Cellular Probes, vol. 11, no. 4, pp. 293–296, 1997 - Detection of four mutations in six unrelated South African patients with acute intermittent porphyria
Molecular and Cellular Probes, vol. 10, no. 1, pp. 57–61, 1996 - Regulation of haem biosynthesis in normoblastic erythropoiesis: role of 5-aminolaevulinic acid synthase and ferrochelatase
Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1201, no. 1, pp. 85–93, 1994 - Acute intermittent porphyria and mental illness ? a family study
Acta Psychiatrica Scandinavica, vol. 89, no. 4, pp. 262–267, 1994 - Drugs and porphyria
Molecular Aspects of Medicine, vol. 11, no. 1-2, pp. 113–123, 1990 - PERIPHERAL BENZODIAZEPINE RECEPTORS AND TREATMENT OF PORPHYRIA
The Lancet, vol. 333, no. 8649, pp. 1264–1265, 1989 - CONTROLLED TRIAL OF HAEM ARGINATE IN ACUTE HEPATIC PORPHYRIA
The Lancet, vol. 333, no. 8650, pp. 1295–1297, 1989 - Haem biosynthesis in the unconjugated hyperbilirubinaemias: Observations in the gunn rat model
Clinical Biochemistry, vol. 22, no. 3, pp. 177–179, 1989 - Therapy of the acute porphyrias
Clinical Biochemistry, vol. 22, no. 3, pp. 181–188, 1989 - The effects of chronic carbamazepine treatment on haem biosynthesis in man and rat
European Journal of Clinical Pharmacology, vol. 35, no. 3, pp. 241–247, 1988 - Lead Effects on the Heme Biosynthetic Pathway Relationship to Toxicity
Annals of the New York Academy of Sciences, vol. 514, no. 1 Mechanisms of, pp. 191–203, 1987 - Lead in water, infant diet and blood: The Glasgow duplicate diet study
The Science of The Total Environment, vol. 41, no. 3, pp. 235–257, 1985 - Successful abatement of lead exposure from water supplies in the West of Scotland
Environmental Research, vol. 38, no. 1, pp. 67–76, 1985 - The acute attack of porphyria
Clinics in Dermatology, vol. 3, no. 2, pp. 103–111, 1985 - Drug therapy in the acute porphyrias
Clinics in Dermatology, vol. 3, no. 2, pp. 112–124, 1985 - Neurotoxic action of lead: Effect on tetrahydrobiopterin metabolism in the rat
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol. 81, no. 1, pp. 227–231, 1985 - CHESTER PORPHYRIA: BIOCHEMICAL STUDIES OF A NEW FORM OF ACUTE PORPHYRIA
The Lancet, vol. 326, no. 8459, pp. 796–799, 1985 - Kinetics of lead following intravenous administration in man
Toxicology Letters, vol. 21, no. 2, pp. 231–235, 1984 - Sex differences in haem biosynthesis and porphyrin content in the harderian gland of the golden hamster
International Journal of Biochemistry, vol. 16, no. 7, pp. 849–852, 1984 - CARBAMAZEPINE AND HAEM BIOSYNTHESIS
The Lancet, vol. 322, no. 8354, p. 846, 1983 - LEAD AND TETRAHYDROBIOPTERIN METABOLISM: POSSIBLE EFFECTS ON IQ
The Lancet, vol. 319, no. 8278, p. 964, 1982 - MATERNAL LEAD LEVELS AFTER ALTERATIONS TO WATER SUPPLY
The Lancet, vol. 318, no. 8239, pp. 203–204, 1981 - ALCOHOL AND PORPHYRIA
The Lancet, vol. 318, no. 8252, p. 925, 1981 - The percutaneous absorption of lead-203 in humans from cosmetic preparations containing lead acetate, as assessed by whole-body counting and other techniques
Food and Cosmetics Toxicology, vol. 18, no. 4, pp. 399–405, 1980 - Seasonal variation in (d minolaevulinate synthase and porphyrin content in the harderan gland of the female golden hamster (mesocricetus auratus)
International Journal of Biochemistry, vol. 12, no. 3, pp. 501–504, 1980 - The activities of the enzymes of haem biosynthesis in the porphyrias and during treatment of acute intermittent porphyrias
International Journal of Biochemistry, vol. 12, no. 5-6, pp. 941–946, 1980 - The effects of selected monopyrroles on various aspects of heme biosynthesis and degradation in the rat
Archives of Biochemistry and Biophysics, vol. 197, no. 1, pp. 132–138, 1979 - The contribution of drinking water lead to maternal blood lead concentrations
Clinica Chimica Acta, vol. 95, no. 1, pp. 129–133, 1979 - Changes in serum aluminium, blood zinc, blood lead and erythrocyte d-aminolaevulinic acid dehydratase activity during haemodialysis
Toxicology Letters, vol. 4, no. 5, pp. 419–424, 1979 - HqMATIN THERAPY AND LEUCOCYTE $delta;-AMINOLqVULINIC-ACID-SYNTHASE ACTIVITY IN PROLONGED ATTACK OF ACUTE PORPHYRIA
The Lancet, vol. 313, no. 8108, pp. 133–134, 1979 - Delta-aminolaevulinic acid metabolism in normal and lead-exposed humans
Toxicology, vol. 9, no. 1-2, pp. 1–9, 1978 - The association between lead concentrations in teeth and domestic water lead concentrations
Clinica Chimica Acta, vol. 87, no. 1, pp. 77–83, 1978 - The biosynthesis of haem in congenital (erythropoietic) porphyria
International Journal of Biochemistry, vol. 9, no. 12, pp. 933–938, 1978 - The carcinogenicity of lead
Archives of Toxicology, vol. 42, no. 2, pp. 87–94, 1978 - The effects of industrial lead poisoning on cytochrome P450 mediated phenazone (antipyrine) hydroxylation
European Journal of Clinical Pharmacology, vol. 12, no. 3, pp. 235–239, 1977 - The storage of samples for blood and water lead analysis
Clinica Chimica Acta, vol. 75, no. 1, pp. 167–170, 1977 - Lead in drinking water in soft water areas—health hazards
The Science of The Total Environment, vol. 7, no. 2, pp. 109–115, 1977 - ENZYME ABNORMALITIES IN THE PORPHYRIAS
The Lancet, vol. 310, no. 8040, pp. 699–701, 1977 - A RETROSPECTIVE ANALYSIS OF BLOOD-LEAD IN MENTALLY RETARDED CHILDREN
The Lancet, vol. 309, no. 8014, pp. 717–719, 1977 - CONTRIBUTION OF LEAD IN DRINKING WATER TO BLOOD-LEAD
The Lancet, vol. 310, no. 8039, pp. 661–662, 1977 - Haem biosynthesis in peripheral blood in erythropoietic protoporphyria
Clinical and Experimental Dermatology, vol. 2, no. 4, pp. 381–388, 1977 - BLOOD-LEAD AND DOMESTIC WATER LEAD
The Lancet, vol. 308, no. 7978, pp. 200–201, 1976 - ROLE OF CHRONIC LOW-LEVEL LEAD EXPOSURE IN THE qTIOLOGY OF MENTAL RETARDATION
The Lancet, vol. 305, no. 7907, pp. 589–592, 1975 - Some pharmacological effects of ?-aminolaevulinic acid on blood pressure in the rat and on rabbit isolated ear arteries
Clinical and Experimental Pharmacology and Physiology, vol. 2, no. 5, pp. 365–371, 1975 - The passage of d-aminolaevulinic acid across the blood brain barrier of the rat: Effect of ethanol
Biochemical Pharmacology, vol. 23, no. 2, pp. 472–474, 1974