Fausto Titti was born in July 27, 1949 in Serra Dè Conti (An), Italy. in 1977, he has got his Summa Cum Laude degree in biological science from the University of Camerino, Italy. Currently, he serves as the Director of Research and Head of the Division of Experimental Retrovirology and Non-Human Primate Models (Core-Laboratory of Virology) at the National AIDS Center, Istituto Superiore Sanità, Rome, Italy. Furthermore, Titti's scientific activities covered different areas of research: i) the pathogenesis of Friend virus in the murine model and the role of host responses in viral infection, ii) the in vivo and in vitro role of IFN-a on viral replication of Friend virus and its effects on basic cell function such as erythroid differentiation, iii) standardization of protocols to evaluate the seroprevalence and the incidence of the HIV-1 infection in Italy and in Africa, iv) incidence of the lentiretroviral coinfections (HIV-1, HIV-2, and HTLV-1), v) biological and molecular characterization of HIV field isolates and of FIV, vi) pathogenesis of the viral and lentiretroviral infections (SIV, HIV, simian EBV, and Type D retrovirus) in preclinical models (mice, rabbits, and nonhuman primate), vii) establishment and development of the SIV-macaca fascicularis as animal model for HIV/AIDS and preparation of vaccine (whole inactivated virus), viii) standardization of protocols to quantitate virus in biological samples from monkeys and to evaluate immune responses, ix) pathogenesis and evaluation of immunogenicity and efficacy of vaccine approaches (whole inactivated virus, live attenuated virus, and genetic vectors) in nonhuman primates (during pregnancy, newborns, adult, male, and female), and x) pathogenesis of simian EBV- and immunodeficiency-associated lymphomas in preclinical models.
Biography Updated on 22 July 2010