Nicola Micale received his Ph.D. degree in pharmaceutical sciences in 2000, at the Medicinal Chemistry Department of the University of Messina, Italy, with a thesis titled Design, synthesis and anticonvulsant activity of new AMPA receptor antagonists. In the next two years, he was a holder of a postdoc fellowship at the same department and extended his doctorate work. From 2002 to 2006, he got a research contract and was involved in the project: New Targets for the Treatment of Neurodegenerative Diseases. In 2003-2004, he joined Professor A. P. Kozikowski, first at the Department of Neurology, Georgetown University Medical Center, Washington DC, USA, then at the Department of Medicinal Chemistry and Pharmacognosy, University of Illinois, Chicago IL, USA, where he worked within the Drug Discovery Program. At that time, he undertook a study on conformationally constrained peptidomimetics as cysteine protease inhibitors. In 2006, he received the the Farmindustria Prize for the quality of his researches in the medicinal chemistry field. In 2007 he was Guest Professor for a 1-year period at the Department of Medicinal Chemistry, the Danish University of Pharmaceutical Sciences of Copenhagen. In 2008, 2009, and 2010, he worked for brief periods as a Visiting Scientist at the Institut für Pharmazie und Lebensmittelchemie, Bayerische Julius-Maximilians-Universität of Würzburg (DE). In 2012, he worked at the Institute of Pharmacy and Biochemistry, University of Mainz (DE), as a scientifically responsible of the joint project Germany-Italy Vigoni 2012-2013. He is coauthor of 47 publications and 41 communications at national and international meetings. Currently, he acts as a Lecturer of medicinal chemistry at the Faculty of Pharmacy, University of Messina. His current research is focused on discovery and development of selective ligands of the glutamate ionotropic receptors and protease-inhibiting drugs including falcipain-2 and 20S proteasome inhibitors.
Biography Updated on 15 October 2012