Masashi Demura was born in Komatsu, Japan, in 1969. He received his MD degree in 1995 and PhD degree in 2002 from Kanazawa University Graduate School of Medical Science. Dr. Demura completed internal medicine residency at Kanazawa University Hospital. From October 2003 to October 2006, he conducted his postdoctoral research at Northwestern University, USA. He works as an endocrinologist in Endocrinology and Metabolism at Kanazawa University Hospital. He is currently an Assistant Professor at Kanazawa University Graduate School of Medical Science. As of 2010, his research on endocrinology including case reports and steroid hormones (estrogen, aldosterone) produced 11 award-winning works at various scientific meetings including the Endcorine Society, the International Society of Endocrinology, the European Society of Hypertension, and the International Society of Hypertension. He is mainly interested in the genetics and epigenetics in endocrinology. He has identified genomic and epigenomic mutations in a variety of endocrine disorders. In 2003, he described the world's first case with pseudohyporarathyroidism type Ib (PHP Ib) who presented incomplete Albright's hereditary osteodystrophy phenotype. That has been proven common in PHP Ib. For the first time ever, he cloned the exact breakpoints of inversion mutations in aromatase excess syndrome. He also uncovered epigenomic alterations as the cause of the pathological activation in aldosterone synthase gene.
Biography Updated on 6 May 2011