Rachel Waddington is a Professor of oral biochemistry and the Director of the postgraduate research studies at the School of Dentistry, Cardiff University, Cardiff, UK. She received the B.S. degree (1984) in biochemistry from the University of Birmingham, UK, and the Ph.D. degree (1988) in oral biochemistry from the University of Liverpool, UK. Waddington's research interests aim to advance the knowledge and understanding of oral mineralised tissues in health, disease, and repair. Her research has concentrated on the cellular biology of bone and dentine and gaining an understanding of the synthesis, extracellular interactions, and subsequent fate of matrix proteins of these tissues in health and disease. Waddington has extensive research expertise in matrix biology of connective tissues, purification and analysis, establishing roles in matrix assembly, regulating cellular behaviour of bone and dentine synthesising cells in health and disease, and the role of the matrix in establishing bacterial infection. Her current research projects include "Understanding the role of the extracellular matrix on stem cell biology for novel approaches for promoting effective bone repair," "Identification of pathogenic mechanisms associated with establishment of infection and periodontal destruction during periodontal disease and peri-implantitis," and "Osseointegration around titanium implants – surface modifications and effect of type 2 diabetes on bone healing."
Biography Updated on 17 January 2013